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SEC16B is a mammalian homolog of S.
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Significant associations were identified at 3.5 years for SEC16B rs10913469 with dietary parameters
SEC16B, MC4R, MAP2K5 and KCTD15 (rs17782313, rs543874, rs2241423 and rs11084753) polymorphisms are associated with the risk for children obesity in China.
Data show the synthetic effect of SNPs on the indices of adiposity and risk of obesity in Chinese girls, but failed to replicate the effect of five separate variants of SEC16B rs10913469, SH2B1 rs4788102, PCSK1 rs6235, KCTD15 rs29941 and BAT2 rs2844479.
describe characterization of the localization and dynamics of Sec16B relative to Sec16A, provide evidence that Sec16B is likely a minor or perhaps specialized form of Sec16, and that it is not functionally redundant with S
Data show that knockdown of Sec16B but not Sec16A by RNAi affected the morphology of peroxisomes, inhibited the transport of Pex16 (show PEX16 Proteins) from the ER to peroxisomes, and suppressed expression of Pex3 (show PEX3 Proteins).
Data show that SNPs in SEC16B and TMEM18 (show TMM18 Proteins) were significantly associated with obesity, and the SNPs in GNPDA2 (show GNPDA2 Proteins), BDNF (show BDNF Proteins), FAIM2 (show FAIM2 Proteins) and MC4R (show MC4R Proteins) were marginally associated with obesity in Japanese.
Mammalian cells contain two distinct Sec16 homologues: a large protein Sec16L of 2154 aa and a smaller protein Sec16S of 1060 aa.
SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007
SEC16 homolog B (S. cerevisiae)
, leucine zipper transcription regulator 2
, protein SEC16 homolog B
, protein transport protein Sec16B
, regucalcin gene promoter region-related protein p117
, regucalcin gene promotor region related protein
, regucalcin gene promotor region related