SET Domain Containing 6 Proteins (SETD6)

Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (By similarity).. Additionally we are shipping SETD6 Antibodies (36) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SETD6 79918 Q8TBK2
SETD6 66083 Q9CWY3
SETD6 291844 D3ZSK5
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Top SETD6 Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$3,254.17
Details
Yeast REACT_Atlantic Salmon His tag   1 mg Log in to see 60 to 71 Days
$3,259.67
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,263.33
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$3,274.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$3,278.00
Details
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$3,294.50
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,336.67
Details

SETD6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for SET Domain Containing 6 (SETD6) Interaction Partners

Human SET Domain Containing 6 (SETD6) interaction partners

  1. Findings suggest that the identified mutation impairs the normal function of SETD6, which may result in the deregulation of the different pathways in which it is involved, contributing to the increased susceptibility to cancer in this FCCTX family.

  2. High SETD6 expression is associated with bladder cancer.

  3. PAK4 (show PAK4 Proteins) methylation by SETD6 promotes the activation of the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway.

  4. these findings demonstrate that SETD6 negatively regulates the Nrf2 (show GABPA Proteins)-mediated oxidative stress response through a physical and catalytically independent interaction with DJ1 (show PARK7 Proteins) at chromatin.

  5. Several chromatin proteins that associate with SETD6 are identified and SETD6 is described as an essential factor for nuclear receptor signaling and cellular proliferation.

  6. SETD6 monomethylates H2AZ (show H2AFZ Proteins) on lysine 7.

  7. SETD6 mono-methylate Rela (show NFkBP65 Proteins) on K310 and negatively regulates RelA (show NFkBP65 Proteins) transcription activity

Mouse (Murine) SET Domain Containing 6 (SETD6) interaction partners

  1. SETD6 monomethylates H2AZ (show H2AFZ Proteins) on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal.

SETD6 Protein Profile

Protein Summary

Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (By similarity).

Gene names and symbols associated with SETD6

  • SET domain containing 6 (SETD6)
  • SET domain containing 6 (Setd6)
  • SET domain containing 6 (setd6)
  • SET domain containing 6 L homeolog (setd6.L)
  • 0610039J04Rik protein
  • 3110004G14Rik protein
  • AI413388 protein
  • C76402 protein
  • RGD1560538 protein
  • wu:fb58f11 protein
  • zgc:55627 protein

Protein level used designations for SETD6

SET domain containing 6 , N-lysine methyltransferase SETD6 , SET domain-containing protein 6 , N-lysine methyltransferase setd6

GENE ID SPECIES
100229419 Taeniopygia guttata
79918 Homo sapiens
66083 Mus musculus
291844 Rattus norvegicus
539651 Bos taurus
415675 Gallus gallus
100306753 Salmo salar
443830 Xenopus laevis
322348 Danio rerio
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