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SOX30 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SRY (Sex Determining Region Y)-Box 30 Proteins (4) and many more products for this protein.
Showing 10 out of 72 products:
Human Polyclonal SOX30 Primary Antibody for ELISA, WB - ABIN545787
Osaki, Nishina, Inazawa, Copeland, Gilbert, Jenkins, Ohsugi, Tezuka, Yoshida, Semba: Identification of a novel Sry-related gene and its germ cell-specific expression. in Nucleic acids research 1999
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Mouse (Murine) Polyclonal SOX30 Primary Antibody for WB - ABIN6687875
Chen, Zheng, Gao, Lin, Yang, Wang, Wang, Xie, Hua, Liu, Sha, Griswold, Li, Tang, Tong: Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis. in Cell research 2018
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Mouse (Murine) Polyclonal SOX30 Primary Antibody for WB - ABIN6148300
Bai, Fu, Yin, Cui, Yue, Li, Cheng, Tan, Liu, Guo, Zhang, Xie, He, Wang, Feng, Xin, Zhang, Lin, Shen, Sun, Guo, Zheng, Ye: Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes. in Development (Cambridge, England) 2018
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MicroRNA-645 represses hepatocellular carcinoma progression by inhibiting SOX30-mediated p53 transcriptional activation
SOX30 displays tumor suppressive behavior, warranting future investigations into its therapeutic potential in the treatment of bladder cancer
In early-stage lung adenocarcinoma patients, elevated SOX30 expression inhibits tumor-metastasis, resulting in a favorable prognosis of these patients.
these results highlight an important role and mechanism of SOX30 in lung cancer metastasis, providing a potential therapeutic target for anti-metastasis.
SOX30 expression represents an important prognostic factor for survival time in lung adenocarcinoma patients.
Blockade of p53 attenuates the tumor inhibition of SOX30.
These results define Sox30 as a crucial transcription factor that controls the transition from a late meiotic to a postmeiotic gene expression program and subsequent round spermatid development.
The results reveal SOX30 as a novel key regulator of spermiogenesis that regulates its own transcription to enforce and activate this meiotic regulatory pathway.
Sox30 expression is under the control of DNA methylation status, and this expression pattern is associated with testis development in mice
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells. Two transcript variants encoding distinct isoforms have been identified for this gene.
Sox30 protein type II
, transcription factor SOX-30
, SRY (sex determining region Y)-box 30
, Sox30 protein