anti-SRY (Sex Determining Region Y)-Box 30 (SOX30) Antibodies

Human SRY (Sex Determining Region Y)-Box 30 (SOX30) interaction partners

1. SOX30 acts as a master switch of desmosomal genes, inhibits lung adenocarcinoma cell proliferation, migration and invasion by activating the transcription of desmosomal genes. This study provides novel insights on the regulatory mechanism of desmosomal genes in lung adenocarcinoma.

2. MicroRNA-645 represses hepatocellular carcinoma progression by inhibiting SOX30-mediated p53 transcriptional activation

3. SOX30 displays tumor suppressive behavior, warranting future investigations into its therapeutic potential in the treatment of bladder cancer

4. In early-stage lung adenocarcinoma patients, elevated SOX30 expression inhibits tumor-metastasis, resulting in a favorable prognosis of these patients.

5. these results highlight an important role and mechanism of SOX30 in lung cancer metastasis, providing a potential therapeutic target for anti-metastasis.

6. SOX30 expression represents an important prognostic factor for survival time in lung adenocarcinoma patients.

7. Blockade of p53 attenuates the tumor inhibition of SOX30.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 30 (SOX30) interaction partners

1. these results highlight an important role and mechanism of SOX30 in lung cancer metastasis, providing a potential therapeutic target for anti-metastasis.

2. These results define Sox30 as a crucial transcription factor that controls the transition from a late meiotic to a postmeiotic gene expression program and subsequent round spermatid development.

3. The results reveal SOX30 as a novel key regulator of spermiogenesis that regulates its own transcription to enforce and activate this meiotic regulatory pathway.

4. Sox30 expression is under the control of DNA methylation status, and this expression pattern is associated with testis development in mice