anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) Antibodies

The protein encoded by ST8SIA4 catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). Additionally we are shipping ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Kits (18) and ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ST8SIA4 20452 Q64692
ST8SIA4 7903 Q92187
ST8SIA4 116696  
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Top anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ST8SIA4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-St8sia4 Antibody   Titration: 1.0 ug/ml   Positive Control: Rat Testis 100 μL Log in to see 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ST8SIA4 Antibody (Center) (ABIN653728) in HL-60 cell line lysates (35 µg/lane). ST8SIA4 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ST8SIA4 Antibody (Center) (ABIN653728) in mouse spleen tissue lysates (35 µg/lane). ST8SIA4 (arrow) was detected using the purified polyclonal antibody. ST8SIA4 Antibody (Center) (ABIN653728) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC (p), WB   0.4 mL Log in to see 8 to 11 Days
$517.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ST8SIA4 Antibody in HL-60 cell line lysates (35ug/lane) Western blot analysis of ST8SIA4 Antibody in mouse spleen tissue lysates (35ug/lane) ST8SIA4 Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB ST8SIA4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Yeast Rabbit Un-conjugated ELISA, WB Western Blot: PST1 Antibody [NBP2-41063] - Western blot analysis of TM yeast Pst1 protein (50 ng) with Pst1 antibody at 1 ug/mL. 0.1 mg Log in to see 8 to 11 Days
$485.88
Details
Bat Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details

More Antibodies against ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Interaction Partners

Mouse (Murine) ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. Mice deficient for ST8SiaIV have impaired long-term spatial memory in two tasks that critically rely on the hippocampus.

  2. Results demonstrate that the early development of calbindin (show CALB1 Antibodies)-positive periglomerular interneurons depends on the presentation of polysialic acid on NCAM (show NCAM1 Antibodies) and requires the activity of both St8sia2 (show ST8SIA2 Antibodies) and St8sia4

  3. NCAM (show NCAM1 Antibodies)-140 significantly promoted cell proliferation, motility and migration, while polysialylation of NCAM (show NCAM1 Antibodies)-140 catalyzed by STX (show ST8SIA2 Antibodies), but not by PST, enhanced NCAM (show NCAM1 Antibodies)-mediated cell migration, but not cell proliferation or motility.

  4. ST8SiaIV synthesized polySia selectively on a NRP2 (show NRP2 Antibodies) glycoform that was characterized by the presence of sialylated core 1 and core 2 O-glycans.

  5. Results indicate that the polySTs ST8SiaII (show ST8SIA2 Antibodies) and ST8SiaIV not only recognize an acidic patch in the FN1 (show FN1 Antibodies) domain of NCAM (show NCAM1 Antibodies) but also must contact sequences in the Ig5 domain for polysialylation of Ig5 N-glycans to occur.

  6. the negative and positive effects of ST8SiaIV overexpression observed during peripheral nerve regeneration suggest that an optimized time- and differentiation-dependent control of expression in Schwann cells may further improve nerve regeneration

  7. While both ST8SiaII (show ST8SIA2 Antibodies) and ST8SiaIV mRNA levels decrease around the time of eye opening in mouse visual cortex, only ST8SiaII (show ST8SIA2 Antibodies) mRNA level reduction is regulated by sensory experience

  8. ST8Sia4 knockout mice display a decreased motivation in social interaction. This deficit can be partly explained by olfactory deficits and was associated with a clear decrease in PSA (show NPEPPS Antibodies)-NCAM (show NCAM1 Antibodies) expression in all brain regions analyzed.

  9. This study demonistrated that mice lacking St8siaIV polysialyltransferase have an accelerated onset of remyelination after cuprizone-induced demyelination.

  10. In summary, the data suggest that the polysialic acid-neural cell adhesion molecule (show MCAM Antibodies) system is a putative target for the modulation of

Human ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 (show ST8SIA2 Antibodies) and ST8SIA4 have been described.

  2. our results demonstrate that miR (show MLXIP Antibodies)-146a and miR (show MLXIP Antibodies)-146b promote proliferation, migration and invasion of FTC (show FUT2 Antibodies) via inhibition of ST8SIA4.

  3. Data show that miR-181c was inversely correlated with the levels of ST8SIA4 expression in chronic myelocytic leukemia (CML) cell lines and samples.

  4. This is the first report to demonstrate a role for a glycosyltransferase (show GTDC2 Antibodies) in human pluripotent stem cell lineage specification.

  5. changes in the glycosylation patterns and sialylation levels may be useful markers of the progression of breast cancer, as well as miR (show MLXIP Antibodies)-26a/26b may be widely involved in the regulation of sialylation machinery by targeting ST8SIA4.

  6. The polybasic region of the polysialyltransferase ST8Sia-IV binds directly to NCAM (show NCAM1 Antibodies).

  7. Sequence Requirements for Neuropilin-2 (show NRP2 Antibodies) Recognition by ST8SiaIV and Polysialylation of Its O-Glycans.

  8. ST8SIA4 gene is involved in the development of multidrug resistance via PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway in chronic myeloid leukemia (show BCL11A Antibodies).

  9. this study indicated that sialylation involved in the development of MDR of AML (show RUNX1 Antibodies) cells probably through ST3GAL5 (show ST3GAL5 Antibodies) or ST8SIA4 regulating the activity of PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling and the expression of P-gp (show ABCB4 Antibodies) and MRP1 (show MDM4 Antibodies).

  10. ST8SiaIV synthesized polySia selectively on a NRP2 (show NELL2 Antibodies) glycoform that was characterized by the presence of sialylated core 1 and core 2 O-glycans.

Pig (Porcine) ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. Pig cDNA provides a basis for uncovering the roles of ST8Sia IV during piglet development and maturation.

ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ST8SIA4

  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (St8sia4) antibody
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (ST8SIA4) antibody
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (st8sia4) antibody
  • pst antibody
  • PST-1 antibody
  • PST1 antibody
  • SIAT8-D antibody
  • SIAT8D antibody
  • siat 8D antibody
  • ST8Sia-IV antibody
  • ST8SiaIV antibody

Protein level used designations for ST8SIA4

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase , alpha-2,8-sialyltransferase 8D , polysialyltransferase-1 , sialyltransferase 8 (alpha-2, 8-sialyltransferase) D , sialyltransferase 8D , sialyltransferase St8Sia IV , sialytransferase St8Sia IV , CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase , SIAT8-D , ST8SiaIV , sialyltransferase 8 (alpha-2, 8-polysialytransferase) D , ST8Sia IV , polysialyltransferase , sialyltransferase 8 (alpha-2 8-polysialyltransferase) D , sialyltransferase 8 (alpha-2 8-polysialytransferase) D , sialyltransferase 8 (alpha-2, 8-polysialyltransferase) D , sialyltransferase 8 (alpha-2, 8-sialytransferase) D , sialyltransferase 8D (alpha-2, 8-polysialyltransferase) , alpha-2,8-polysialyltransferase IV , polysialyltransferase 1 , N-glycan alpha 2,8-sialyltransferase , alpha-2,8-sialyltransferase ST8Sia IV , CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase-like protein

GENE ID SPECIES
20452 Mus musculus
7903 Homo sapiens
407768 Bos taurus
116696 Rattus norvegicus
374155 Gallus gallus
488886 Canis lupus familiaris
641356 Sus scrofa
461971 Pan troglodytes
101112314 Ovis aries
100716689 Cavia porcellus
553211 Danio rerio
100064780 Equus caballus
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