Sarcoglycan, epsilon Proteins (SGCE)

SGCE encodes the epsilon member of the sarcoglycan family. Additionally we are shipping SGCE Antibodies (32) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SGCE 8910 O43556
SGCE 20392 O70258
Rat SGCE SGCE 432360 Q6YAT4
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top SGCE Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Cynomolgus His tag   1 mg Log in to see 60 to 71 Days
$2,849.00
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,849.00
Details

SGCE Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)
,

More Proteins for Sarcoglycan, epsilon (SGCE) Interaction Partners

Human Sarcoglycan, epsilon (SGCE) interaction partners

  1. The characterization of iPSC-derived cortical neurons with mutations in SGCE revealed that these cells are a suitable model mirroring the endogenous environment in the myoclonus-dystonia patient brain, especially, when focusing on concrete molecular aspects of the disease mechanism.

  2. A novel nonsense SGCE mutation was found in a Japanese family with myoclonus-dystonia.

  3. This study demonstrated that Psychiatric features are not likely to be related with the SGCE mutation itself but just bespeak disability in clinical MD syndrome regardless of the SGCE mutation.

  4. SGCE mutation can cause a broad range of clinical symptoms between and within families. We should consider MDS as a differential diagnosis for patients with paroxysmal walking abnormalities and/or myoclonic movements.

  5. Tata confirms that SGCE mutations are most commonly identified in Myoclonus dystonia syndrome patients with (1) age at onset

  6. found one patient with a novel heterozygous frameshift mutation in the DYT11 gene

  7. The co-occurrence of seizures and myoclonus-dystonia suggests that they are both due to the same underlying SGCE mutation

  8. A novel frameshift mutation of the SGCE gene in an Iranian family with Myoclonus-dystonia syndrome confirming the variability of the clinical symptoms caused by the same mutation within members of a family.

  9. In myoclonus-dystonia syndrome patients a substantial mutation in exon 3 of SGCE gene was found.

  10. The results of this study suggested performing gene dosage analysis by multiple ligation-dependent probe amplification (MLPA) to individuate large SGCE deletions that can be responsible for complex phenotypes.

  11. SGCE mutations are associated with a specific psychiatric phenotype consisting of compulsivity, anxiety and alcoholism in addition to the characteristic motor phenotype.

  12. Although reduced penetrance in DYT11-MD has been attributed to the maternal imprinting epsilon-sarcoglycan mutations, NM-DYT11 carriers showed significant metabolic abnormalities that are not explained by this genetic model.

  13. anxiety disorders and executive dysfunctions may be part of the phenotype of myoclonus-dystonia patients with a DYT11 mutation

  14. The results of this review confirmed the association of epsilon-sarcoglycan gene mutations with psychiatric disease and suggest a possible separation of the motor and psychiatric effects.

  15. This report presents a novel mutation in the SGCE gene causing myoclonus dystonia and extends the phenotype of myoclonus dystonia to also include alcohol-induced dystonia.

  16. Dystonia severity in twenty-five clinically affected DYT11 mutation carriers is strongly correlated with increased gray matter volume in bilateral putamina.

  17. This study demonistrated that Familial 7q21.3 microdeletion involving epsilon-sarcoglycan causing myoclonus dystonia, cognitive impairment, and psychosis.

  18. the mRNA expression level of SGCE were significantly up-regulated in tumorous liver tissues compared with corresponding nontumorous counterparts

  19. This study provides the first neurophysiological evidence of cerebellar dysfunction in DYT11 dystonia and supports a role of cerebellar dysfunction in the myoclonus-dystonia phenotype.

  20. Biased SGCE gene expression is based on parent of origin rather than on a strictly dichotomous maternal imprinting mechanism, consistent with clinical observations.

Pig (Porcine) Sarcoglycan, epsilon (SGCE) interaction partners

  1. Paternal expression was demonstrated by microarray profiling of swine parthenotes and bi-parental fetal tissues and by an orthogonal method (QUASEP) with reciprocal interbreed crosses.

SGCE Protein Profile

Protein Summary

This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Sarcoglycan, epsilon Proteins (SGCE)

  • sarcoglycan, epsilon (sgce)
  • sarcoglycan epsilon S homeolog (sgce.S)
  • sarcoglycan epsilon (SGCE)
  • sarcoglycan, epsilon (Sgce)
  • DYT11 protein
  • e-SG protein
  • ESG protein
  • scge protein
  • zgc:92318 protein

Protein level used designations for Sarcoglycan, epsilon Proteins (SGCE)

Epsilon-sarcoglycan , epsilon-sarcoglycan , dystonia 11, myoclonic , epsilon-SG

GENE ID SPECIES
100380447 Salmo salar
368230 Danio rerio
734393 Xenopus laevis
8910 Homo sapiens
475233 Canis lupus familiaris
100240725 Sus scrofa
407209 Bos taurus
20392 Mus musculus
432360 Rattus norvegicus
Selected quality suppliers for SGCE Proteins (SGCE)
Did you look for something else?