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SFMBT1 shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Additionally we are shipping Scm-Like with Four Mbt Domains 1 Antibodies (40) and Scm-Like with Four Mbt Domains 1 Kits (6) and many more products for this protein.
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copy number variation analysis identified deletions in SFMBT1 associated with fasting plasma glucose in a Han Chinese population
The present study demonstrates that a copy number loss within intron 2 of the SFMBT1 gene may be a genetic risk factor for shunt-responsive definite iNPH.
The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition.
When bound to its gene targets, SFMBT1 recruits its associated proteins and causes chromatin compaction and transcriptional repression
novel mechanisms accounting for SFMBT1-mediated transcription repression and revealed an essential role of Sfmbt1 in regulating MyoD-mediated transcriptional silencing
Data identified IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes by gene based association scan and gene expression analysis.
A segmental copy number loss of the SFMBT1 gene may be involved in the pathological process in some individuals with ventriculomegaly/idiopathic normal pressure hydrocephalus.
The tandem MBT repeats form a functional structure required for biological activity of hSFMBT and predict similar properties for other MBT domain-containing proteins.
This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition.
Scm-like with four mbt domains 1
, scm-like with four MBT domains protein 1-like
, Scm-related gene containing four mbt domains
, Scm-related gene product containing four mbt domains
, renal ubiquitous protein 1
, scm-like with four MBT domains protein 1
, Scm-related gene containing four mbt domains 1