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Sec23 Homolog B (S. Cerevisiae) Proteins (SEC23B)

The protein encoded by SEC23B is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. Additionally we are shipping Sec23 Homolog B (S. Cerevisiae) Antibodies (38) and Sec23 Homolog B (S. Cerevisiae) Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEC23B 10483 Q15437
Rat SEC23B SEC23B 362226  
SEC23B 27054 Q9D662
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Top Sec23 Homolog B (S. Cerevisiae) Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
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Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
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SEC23B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Sec23 Homolog B (S. Cerevisiae) (SEC23B) Interaction Partners

Human Sec23 Homolog B (S. Cerevisiae) (SEC23B) interaction partners

  1. described the functional interaction between GATA1 (show GATA1 Proteins) and SEC23B genes in two patients with suspected congenital dyserythropoietic anemia type II

  2. these data demonstrate an equivalent function for SEC23A (show SEC23A Proteins)/B, with evolutionary shifts in the transcription program likely accounting for the distinct phenotypes of SEC23A (show SEC23A Proteins)/B deficiency within and across species, a paradigm potentially applicable to other sets of paralogous genes.

  3. novel compound mutations of c.1727T>C and c.1831C>T of the SEC23B gene probably underlie the congenital dyserythropoietic anemia type II in the family

  4. Mutation in SEC23B gene is associated with congenital dyserythropoietic anemia.

  5. miR (show MLXIP Proteins)-130a is an epigenetically regulated miRNA involved in regulation of key molecular and phenotypic features of prostate carcinogenesis, acting as a tumour suppressor miRNA by targeting SEC23B and DEPDC1 (show DEPDC1 Proteins).

  6. SEC23B-Y462C congenital dyserythropoietic anemia type II is only seen in a distinct Indian community (Vaish) in whom a recessively inherited shared haplotype can be showed, consistent with a founder effect.

  7. Germline Heterozygous Variants in SEC23B Are Associated with Cowden Syndrome and Enriched in Apparently Sporadic Thyroid Cancer.

  8. Congenital dyserythropoietic anemia, type II with SEC23B exon 12 c.1385 A --> G mutation, and pseudo-Gaucher cells in two siblings has been described.

  9. ALG-2 (show PDCD6 Proteins) attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A (show SEC31A Proteins) complex.

  10. Both probands with congenital dyserythropoietic anemia IotaI in the second family were homozygotes of the SEC23B gene with mutation c.938G>A (R313H).

Mouse (Murine) Sec23 Homolog B (S. Cerevisiae) (SEC23B) interaction partners

  1. these data demonstrate an equivalent function for SEC23A (show SEC23A Proteins)/B, with evolutionary shifts in the transcription program likely accounting for the distinct phenotypes of SEC23A (show SEC23A Proteins)/B deficiency within and across species, a paradigm potentially applicable to other sets of paralogous genes.

  2. SEC23B but not SEC23A (show SEC23A Proteins) is essential for murine pancreatic development.

  3. Acinar Sec23b deletion results in induction of ER stress and increased apoptosis in the pancreas, potentially explaining the loss of pancreatic cells and decreased pancreatic weight. These findings demonstrate that SEC23B is required for normal function of pancreatic acinar cells in adult mice.

  4. Results show that transplantation of SEC23B-deficient hematopoietic stem cells does not result in a hematopoietic stem cells phenotype.

  5. In SEC23B-deficient embryonic pancreas, defects occur in exocrine and endocrine tissues shortly after differentiation.

Sec23 Homolog B (S. Cerevisiae) (SEC23B) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene.

Gene names and symbols associated with SEC23B

  • Sec23 homolog B, COPII coat complex component L homeolog (sec23b.L)
  • Sec23 homolog B, coat complex II component (SEC23B)
  • Sec23 homolog B, COPII coat complex component (sec23b)
  • Sec23 homolog B, coat complex II component (Sec23b)
  • SEC23 homolog B, COPII coat complex component (Sec23b)
  • CDA-II protein
  • CDAII protein
  • CDAN2 protein
  • HEMPAS protein
  • SEC23A protein
  • wu:fd19h01 protein
  • wu:fl08h02 protein
  • zgc:55595 protein
  • zgc:86871 protein

Protein level used designations for SEC23B

SEC23-like protein B , SEC23-related protein B , protein transport protein Sec23B , transport protein SEC23B , SEC23B , fl08h02 , SEC23-related protein A , protein transport protein Sec23A

GENE ID SPECIES
444834 Xenopus laevis
10483 Homo sapiens
327268 Danio rerio
416724 Gallus gallus
477142 Canis lupus familiaris
535071 Bos taurus
362226 Rattus norvegicus
27054 Mus musculus
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