Sec61 alpha 1 Subunit (S. Cerevisiae) Proteins (SEC61A1)

The protein encoded by SEC61A1 belongs to the SECY/SEC61- alpha family. Additionally we are shipping Sec61 alpha 1 Subunit (S. Cerevisiae) Antibodies (42) and many more products for this protein.

list all proteins	Gene Name	GeneID	UniProt
	SEC61A1	29927	P61619
	SEC61A1	53421	P61620
Rat SEC61A1	SEC61A1	80843	P61621

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Top Sec61 alpha 1 Subunit (S. Cerevisiae) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No.	Origin	Source	Conjugate	Quantity	Supplier	Delivery	Price	Details
ABIN3120715	Insect Cells	Mouse	rho-1D4 tag	0.25 mg	Log in to see	50 to 55 Days	$4,649.05	Details
ABIN3076443	Insect Cells	Human	rho-1D4 tag	0.5 mg	Log in to see	50 to 55 Days	$6,616.87	Details
ABIN1319426	Wheat germ	Human	GST tag	2 μg	Log in to see	11 to 12 Days	$338.33	Details

SEC61A1 Proteins by Origin and Source

Origin	Expressed in	Conjugate
Human	,	,
Mouse (Murine)

More product categories related to Sec61 alpha 1 Subunit (S. Cerevisiae) Protein

More Proteins for Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) Interaction Partners

Human Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) interaction partners

The authors propose that the Sec61-IRE1alpha (show ERN1 Proteins) complex defines the extent of IRE1alpha (show ERN1 Proteins) activity and may determine cell fate decisions during endoplasmic reticulum stress conditions.
EPO (show EPO Proteins) (7q22) and SEC-61(7p11) emerged as new candidate genes susceptible to genetic losses with 57.7% deletions identified in regions on chromosome 7.
Tomography densities at subnanometer resolution revealed an intricate network of interactions between the ribosome, Sec61 and accessory translocon components that assist in protein transport, membrane insertion and maturation
The discovery of export-specific sec61 mutants and of mammalian ER-associated degradation (ERAD) substrates whose export is dependent on the 19S regulatory particle suggest that dismissal of a role of Sec61 in export may have been premature.
the effect of mycolactone on transmembrane protein biogenesis depends on how the nascent chain initially engages the Sec61 complex.
data provide definitive genetic evidence that Sec61 is the host receptor mediating the diverse immunomodulatory effects of mycolactone and identify Sec61 as a novel regulator of immune cell functions.
findings provide a mechanism by which mutations in SEC61A1 lead to an autosomal-dominant syndromic form of progressive chronic kidney disease; we highlight protein translocation defects across the endoplasmic reticulum membrane, the principal role of the SEC61 complex, as a contributory pathogenic mechanism for autosomal-dominant tubulo-interstitial kidney disease
Nuclear envelope associated endosome-mediated transfer depends on the nuclear envelope proteins SUN1 (show SUN1 Proteins) and SUN2 (show SUN2 Proteins), as well as the Sec61 translocon complex.
Cotransin, a substrate-selective Sec61 inhibitor, traps nascent transmembrane domains in the cytosolic vestibule, permitting detailed interrogation of an early pre-integration intermediate.
BiP (show GDF10 Proteins) facilitates Sec61 channel closure (i.e. limits ER Ca(2 (show CA2 Proteins)+) leakage) via the Sec61 channel with the help of ERj3 (show DNAJB11 Proteins) and ERj6

Mouse (Murine) Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) interaction partners

Interaction of ribosomes and Sec62 (show TLOC1 Proteins) with the core Sec61 translocon is mutually exclusive.
SEC61A1 gene silencing inhibits co- and post-translational transport of presecretory proteins into endoplasmic reticulum.
Diabetes can bemapped to a point mutation in the Sec61a1 gene that encodes a His to Tyr (show TYR Proteins) substitution at amino acid 344.

Zebrafish Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) interaction partners

A screen for mutations that affect habenular laterality led to the identification of the sec61a-like 1(sec61al1) gene.

Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.

Gene names and symbols associated with SEC61A1

Sec61 translocon alpha 1 subunit (SEC61A1)
Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1)
Sec61 translocon alpha 1 subunit (Sec61a1)
Sec61 translocon alpha 1 subunit S homeolog (sec61a1.S)
Sec61 translocon alpha 1 subunit (sec61a1)
preprotein translocase subunit SecY (HVO_RS16965)
Sec61 alpha 1 subunit (Sec61a1)
translocon subunit (SEC61)
translocon alpha subunit Sec61 (sec61)

AA408394 protein
AA410007 protein
chunp6898 protein
fb62c11 protein
HSEC61 protein
sec61 protein
sec61a protein
SEC61A1 protein
sec61al1 protein
sec61alpha protein
secY1 protein
wu:fb62c11 protein

Protein level used designations for SEC61A1

Sec61 alpha-1 , protein transport protein SEC61 alpha subunit , protein transport protein Sec61 subunit alpha , protein transport protein Sec61 subunit alpha isoform 1 , sec61 homolog , SEC61, alpha subunit , sec61 alpha-1 , transport protein sec61 alpha subunit , Sec61 alpha subunit homolog , sec61 homologue , Sec61 alpha 1 subunit (S. cerevisiae) , Sec61 alpha form 1 , transport protein Sec61 alpha subunit , Protein transport protein Sec61 subunit alpha , protein transport protein Sec61 subunit alpha-like , Sec61 alpha like 1 , protein transport protein Sec61 subunit alpha-like 1 , hypothetical protein

GENE ID	SPECIES
29927	Homo sapiens
53421	Mus musculus
80843	Rattus norvegicus
379936	Xenopus laevis
404006	Canis lupus familiaris
416023	Gallus gallus
448033	Xenopus (Silurana) tropicalis
460669	Pan troglodytes
505064	Bos taurus
8925650	Haloferax volcanii DS2
100144911	Acyrthosiphon pisum
100155306	Sus scrofa
100173741	Pongo abelii
100413259	Callithrix jacchus
100603743	Nomascus leucogenys
192298	Danio rerio
3647462	Candida albicans SC5314
2541037	Schizosaccharomyces pombe 972h-
100723492	Cavia porcellus

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