anti-Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) Antibodies

SCGB1A1 encodes a member of the secretoglobin family of small secreted proteins. Additionally we are shipping SCGB1A1 Kits (44) and SCGB1A1 Proteins (33) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCGB1A1 7356 P11684
SCGB1A1 22287 Q06318
SCGB1A1 25575 P17559
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Top anti-SCGB1A1 Antibodies at antibodies-online.com

Showing 10 out of 148 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry with Lung, respiratory epithelium tissue at an antibody concentration of 5µg/ml using anti-SCGB1A1 antibody (ARP41524_P050) Host:  Rabbit  Target Name:  SCGB1A1  Sample Type:  Human Thyroid  Antibody Dilution:  2.0 ug/ml 100 μL 2 to 3 Days
$319.00
Details
Human Mouse Un-conjugated FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of A549 cells using SCGB1A1 mouse mAb (green) and negative control (red) . 0.1 mg 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated ELISA, FACS 100 μg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Anti-SCGB1A1 / Uteroglobin antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959025 concentration 5 ug/ml. Anti-SCGB1A1 / Uteroglobin antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconj ... 100 μL 11 to 14 Days
$727.83
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat lung labeled with Anti-CC16/CCSP Polyclonal Antibody, Unconjugated (ABIN687262) followed by conjugation to the secondary antibody and DAB staining Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 100 μL 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of extracts of mouse lung , using SCGB1A1 antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276844 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Lung, Airway: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μg 11 to 14 Days
$639.83
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. HE staining on IHC-P;;Samples: Human Lung Tissue. 100 μg 15 to 18 Days
$316.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Lung tissue 100 μg 15 to 18 Days
$324.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg 15 to 18 Days
$342.00
Details

Top referenced anti-SCGB1A1 Antibodies

  1. Human Monoclonal SCGB1A1 Primary Antibody for FACS, ELISA - ABIN1098131 : Paantjens, Otten, van Ginkel, van Kessel, van den Bosch, Kwakkel-van Erp, van de Graaf: Clara cell secretory protein and surfactant protein-D do not predict bronchiolitis obliterans syndrome after lung transplantation. in Transplantation 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal SCGB1A1 Primary Antibody for ELISA - ABIN563338 : Archer, Abi-Rizk, Desloire, Dolmazon, Gineys, Guiguen, Cottin, Mornex, Leroux: Lung progenitors from lambs can differentiate into specialized alveolar or bronchiolar epithelial cells. in BMC veterinary research 2014 (PubMed)

  3. Mouse (Murine) Polyclonal SCGB1A1 Primary Antibody for IF (p), IHC (p) - ABIN687262 : Mori, Sasaki, Makabe, Yoshinari, Yajima: The genes Scgb1a1, Lpo and Gbp2 characteristically expressed in peri-implant epithelium of rats. in Clinical oral implants research 2015 (PubMed)

  4. Human Monoclonal SCGB1A1 Primary Antibody for IA, IHC (fro) - ABIN2192038 : Geerts, Jorens, Willems, De Ley, Slegers: Natural inhibitors of neutrophil function in acute respiratory distress syndrome. in Critical care medicine 2001 (PubMed)

More Antibodies against SCGB1A1 Interaction Partners

Human Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. Long-term exposure to silica dust may lead to a decrease in serum CC16 levels

  2. Long-term exposure to silica dust may result in a reduction in CC16 levels in serum; additionally, CC16 can be used as a blood serum biomarker for higher accuracy in the diagnosis of silicosis.

  3. Low serum CC16 was associated with smoking-related decline in lung function, demonstrated the first time in a Chinese cohort. The data also lend support to the putative role of CC16 in protection against smoking-related bronchial epithelial damage.

  4. Concentrations of CC-16 and IL-6 were higher in grain dust exposed workers

  5. Donor CCSP G38A polymorphism is associated with a decreased risk of severe primary graft dysfunction after lung transplantation in a French cohort study

  6. In dramatic expansion of an SCGB1A1+ airway cell population.

  7. Serum CC-16 levels were significantly lower in patients with Asthma and COPD overlap and in those with severe obstruction with high reversibility and frequent exacerbations. Decreased serum CC-16 could possibly distinguish patients with Asthma and COPD overlap or frequent exacerbators in chronic inflammatory airway diseases.

  8. The uteroglobin gene may play an important role in the development of childhood idiopathic nephrotic syndrome, and the AA genotype of UG gene G38A polymorphism was found more frequently in those children

  9. There was no evidence that serum CC16 levels played a role in recurrent wheezing and a positive asthma predictive index in pre-school children

  10. Data suggest that the increase in plasma club cell protein (CC16) CC16 following inhaled allergen as a biomarker of epithelial dysfunction.

  11. We propose that increased CC-16 levels is a marker of lung inflammatory response that associated with ventilatory insufficiency are related to impending respiratory failure, not fully predicted by conventional respiratory tests

  12. Studied serum CC16 levels in The serum CC16 levels in Acute respiratory distress syndrome (ARDS) and non-ARDS patients; found CC16 to be were significantly higher in ARDS patients than that in non-ARDS patients.

  13. Studied serum CC16 levels in relation to atopy and previously manifested low respiratory tract diseases. Found low serum CC16 is associated with previously expressed pneumonia and chronic wheezing in atopic children.

  14. Our data suggest that rCC16 suppresses LPS-mediated inflammatory mediator TNF-alpha, IL-6, and IL-8 production by inactivating NF-kappaB and p38 MAPK but not AP-1 in RAW264.7 cells.

  15. There were associations between urinary CC16 and arsenic concentration in soil, water, house dust, and dust loading. In multiple analyses, only the concentration of arsenic in soil was associated with urinary CC16 levels after accounting for other factors.

  16. findings demonstrate that CC16 is upregulated in IPF patients suggesting that may participate in its pathogenesis.

  17. The G38A CCSP gene polymorphism may alter either the production of the protein and/or its activity in chronic obstructive pulmonary disease.

  18. CC16 levels differed among idiopathic pulmonary fibrosis, pulmonary sarcoidosis and chronic pulmonary obstructive disease.

  19. Lung-specific (CC-16) and novel (RelB) biomarkers are associated with systemic cardiovascular changes over time. CC-16 can predict subsequent exacerbations in subjects with severe COPD and may be an important biomarker of pulmonary and systemic stress in COPD.

  20. The serum concentration of CC16 was significantly higher in patients with lung fibrosis.

Horse (Equine) Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. role of Secretoglobin 1A1 and 1A1A in neutrophil reactive oxygen species production, phagocytosis and extracellular trap formation [secretoglobin 1A1][secretoglobi 1A1A]

Rabbit Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. In the oviduct tissue, a decrease in the level of SCGB1A1 mRNA expression was observed from 144 h post-ovulation.In the endometrium a significant decline in the level of SCGB1A1 mRNA expression from 16 to 144 h post-ovulation induction was observed.

Mouse (Murine) Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. In the mouse fulminant hepatitis (FH) model revealed that CC10 protects against MHV-3-induced FH via suppression of Fgl2 expression in macrophages. In vitro, CC10 was found to significantly inhibit the expression of Fgl2 in MHV-3-infected mouse peritoneal macrophages. Such effects may be mediated by the transcription factor HBP1.

  2. the present results demonstrate that rCC16 has therapeutic effects on COPD by downregulating proinflammatory factors via the NFkappaB pathway.

  3. This study extends the function of the Scgb1a1-expressing epithelial cell population as a major mediator of the antiviral response. It

  4. Chronic P. aeruginosa inflammation resulted in chronic bronchitis and emphysematous changes in CCSP-deficient mice.

  5. CC16 protects lungs from cigarette smoke (CS)-induced injury by reducing lung NF-kappaB activation. CS-induced airway CC16 deficiency increases CS-induced pulmonary inflammation and injury and likely contributes to the pathogenesis of COPD.

  6. Depletion of bone marrow CCSP-expressing cells delays airway regeneration.

  7. Suggest role for Scgb1a1(+) cells in the generation of p63(+) cells in the damaged lung parenchyma.

  8. Serum CC-16 is associated with disease progression in chronic obstructive pulmonary disease (COPD). However, the absence of CC-16 does not appear to modify the risk of cigarette-related COPD in mice.

  9. These findings indicate that CCSP has a regulatory role in obliterative bronchiolitis.

  10. the role of clara cells and clara cell secretory protein in lung radiation injury exacerbated by viral infection

  11. AAV2/9-CC10 vector virus guaranteed sufficient CC10 expression and had an anti-inflammatory effect in asthmatic mice.

  12. Claudin-3 and Clara cell 10 kDa protein were identified as possible markers of early tobacco smoke-induced epithelial injury along alveolar ducts.

  13. Scgb1a1-expressing cells, most likely Clara cells, are a major cell type that gives rise to alveolar type I and II cells during the regeneration of alveolar epithelia in response to severe pulmonary damage in mice.

  14. These results indicate that CC10 gene transfer may inhibit airway inflammation through suppressing the activation of NF-kappaB.

  15. Clara cell secretory protein expression is elevtaed in lungs after long-term n-hexane inhalation exposure.

  16. CCSP promoter has a role in alveolar development

  17. The expression of CC10 is downregulated in sinonasal mucosa in bacterial chronic rhinosinusitis.

  18. Expression of SCGB1A1 mRNA was not decreased in vivo in the absence of C/EBPs.

  19. In the context of allergic airway responses, CC10 can inhibit OPN expression and suppress the Th2-promoting function of OPN, resulting in CC10's inhibitory biological effects.

  20. The differential expression of mRNA by both airway level and lung region was determined for Clara cell secretory protein.

SCGB1A1 Antigen Profile

Protein Summary

This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.

Gene names and symbols associated with SCGB1A1

  • secretoglobin family 1A member 1 (SCGB1A1) antibody
  • secretoglobin, family 1A, member 1 (uteroglobin) (SCGB1A1) antibody
  • secretoglobin, family 1A, member 1 (uteroglobin) (Scgb1a1) antibody
  • secretoglobin family 1A member 1 (Scgb1a1) antibody
  • CC10 antibody
  • CC16 antibody
  • CCPBP antibody
  • CCSP antibody
  • PCB-BP antibody
  • PCBB antibody
  • SCGB1A1 antibody
  • UG antibody
  • Ugb antibody
  • UGL antibody
  • UP-1 antibody
  • UP1 antibody
  • Utg antibody

Protein level used designations for SCGB1A1

blastokinin , clara cell phospholipid-binding protein , clara cells 10 kDa secretory protein , urinary protein 1 , urine protein 1 , uteroglobin , secretoglobin family 1A member 1 , Blastokinin , CCPBP , PCB-binding protein , clara cell 17 kDa protein , clara cell secretory protein , Uteroglobin (Clara cell secretory protein) , secretoglobin, family 1A, member 1 (uteroglobin)

GENE ID SPECIES
7356 Homo sapiens
767867 Bos taurus
100033916 Equus caballus
100009053 Oryctolagus cuniculus
22287 Mus musculus
25575 Rattus norvegicus
466634 Pan troglodytes
476060 Canis lupus familiaris
100431098 Ovis aries
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