Secretoglobin, Family 3A, Member 1 Proteins (SCGB3A1)

SCGB3A1 encodes a small secreted protein that may function in the inhibition of cell growth. Additionally we are shipping SCGB3A1 Antibodies (37) and SCGB3A1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCGB3A1 92304 Q96QR1
SCGB3A1 68662 Q920D7
Rat SCGB3A1 SCGB3A1 338418  
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Top SCGB3A1 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Human Cells Human Fc Tag 100 μg Log in to see 14 to 16 Days
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

SCGB3A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

More Proteins for Secretoglobin, Family 3A, Member 1 (SCGB3A1) Interaction Partners

Human Secretoglobin, Family 3A, Member 1 (SCGB3A1) interaction partners

  1. Some single nucleotide polymorphisms and their combinations in the Ugrp2 gene are associated with an increased risk of developing adenoid hypertrophy.

  2. The role of high in normal-1 (HIN-1) as a potential biomarker in combating glioblastoma is being described for the first time in this study.

  3. Tumor-adjacent tissues showed higher methylation status of RASSF1A, HIN-1 and MGMT promoters.

  4. SCGB3A1-183 T and SCGB3A1 IVS1-189 A alleles might have a protective effect against nasal polyposis.

  5. aberrant HIN-1 promoter methylation could be an independent and important biomarker used in predicting the prognosis and progression of breast cancer

  6. Methylation of HIN-1 promoter is a novel epigenetic biomarker associated with poor outcomes in OCCA patients.

  7. Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancers was associated with clinical characteristics, but only RASSF1A methylation was associated with time to first recurrence and overall survival.

  8. HIN1, was the most "dietary sensitive" genes, as methylation of their promoters was associated with intakes of at least two out of the eight dietary methyl factors examined.

  9. analysis of AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer

  10. Data show that SCGB3A1 was down-regulated in invasive compared with DCIS, whereas talin 2 (TLN2) and PTGS1 were up-regulated in invasive compared with DCIS.

  11. Data suggest that high methylation of the HIN-1 promoter results in silenced HIN-1 expression in gastric cancer, and that 5-aza-2'-deoxycytidine reverses HIN-1 methylation and reduces viability of gastric cancer cells.

  12. The methylation levels and frequencies of HIN1, RASSF1A and TWIST, and average MR were significantly lower in basal-like subtype compared to luminal or human epithelial growth factor receptor-2 subtype.

  13. Hypermethylation of HIN-1 is associated with lymphatic metastasis of breast cancers.

  14. HIN-1, RAR-beta, RASSF1A, and Twist had the ability to distinguish high-grade squamous intraepithelial lesions/squamous cell carcinomas from low-grade squamous intraepithelial lesions/negative cervical scrapings

  15. Sporadic breast tumors with a "BRCA1-like" histopathological phenotype also demonstrated significantly lower frequency of HIN-1 promoter methylation.

  16. hypermethylated in invasive and in in situ lobular breast cancer

  17. Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors

  18. high in normal-1 (HIN-1) is downregulated in stage I non-small cell lung cancer

  19. silencing of HIN-1 expression and methylation of its promoter occurs in multiple human cancer types, suggesting that elimination of HIN-1 function may contribute to several forms of epithelial tumorigenesis

  20. Aberrant methylation of HIN-1 is a frequent event in many human malignancies

Mouse (Murine) Secretoglobin, Family 3A, Member 1 (SCGB3A1) interaction partners

  1. Neonatal hyperoxia followed by RA recovery was associated with decreased lung CCSP and SCGB3A1 protein but not mRNA expression.

  2. The differential expression of mRNA by both airway level and lung region was determined for uteroglobin-related protein 2.

  3. Highest HIN-1 and UGRP-1 expression is detected in the lung, while lower level HIN-1 expression is also detected in the stomach, heart, small intestine, uterine and mammary glands

  4. genomic structure and expression patterns of Ugrp2 and its alternative spliced form were characterized

  5. EGF-induced increase of Ugrp2 occurred at the transcriptional level that required the EGF receptor and the activation of the ERK-MAPK and phosphoinositide-3 kinase pathways

  6. ubiquitous transcription factor NF-Y binds to and activates expression of the Scgb3a1 gene and tissue-specific expression of the gene is associated with CpG methylation of the promoter

  7. The expression of SCGB3A1 and SCGB3A2 are bidirectionally regulated by oncostatin M (OSM) when examined in a mouse transformed Clara cell line.

  8. Expression of SCGB3A1 was down-regulated by IFN-gamma in a time- and dose-dependent manner in the murine transformed Clara Cells line.

SCGB3A1 Protein Profile

Protein Summary

This gene encodes a small secreted protein that may function in the inhibition of cell growth. Expression of the related gene in humans is downregulated via DNA methylation in breast cancers and other tumor types. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with SCGB3A1

  • secretoglobin family 3A member 1 (SCGB3A1)
  • secretoglobin, family 3A, member 1 (Scgb3a1)
  • HIN-1 protein
  • Hin1 protein
  • LU105 protein
  • LuLeu2 protein
  • PnSP-2 protein
  • Pnsp2 protein
  • secretoglobin protein
  • UGRP2 protein
  • Utgrp2 protein

Protein level used designations for SCGB3A1

cytokine HIN-1 , cytokine high in normal-1 , high in normal 1 , pneumo secretory protein 2 , secretoglobin family 3A member 1 , uteroglobin-related protein 2 , uteroglobin related protein 2

92304 Homo sapiens
68662 Mus musculus
338418 Rattus norvegicus
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