Secretoglobin, Family 3A, Member 1 Proteins (SCGB3A1)

Human Secretoglobin, Family 3A, Member 1 (SCGB3A1) interaction partners

1. The role of high in normal-1 (HIN-1) as a potential biomarker in combating glioblastoma is being described for the first time in this study.

2. Tumor-adjacent tissues showed higher methylation status of RASSF1A (show RASSF1 Proteins), HIN-1 (show OTUD4 Proteins) and MGMT (show MGMT Proteins) promoters.

3. SCGB3A1-183 T and SCGB3A1 IVS1-189 A alleles might have a protective effect against nasal polyposis.

4. aberrant HIN-1 (show OTUD4 Proteins) promoter methylation could be an independent and important biomarker used in predicting the prognosis and progression of breast cancer

5. Methylation of HIN-1 (show OTUD4 Proteins) promoter is a novel epigenetic biomarker associated with poor outcomes in OCCA patients.

6. Methylation of HIN-1 (show OTUD4 Proteins), RASSF1A (show RASSF1 Proteins), RIL (show PDLIM4 Proteins) and CDH13 (show CDH13 Proteins) in breast cancers was associated with clinical characteristics, but only RASSF1A (show RASSF1 Proteins) methylation was associated with time to first recurrence and overall survival.

7. HIN1 (show OTUD4 Proteins), was the most "dietary sensitive" genes, as methylation of their promoters was associated with intakes of at least two out of the eight dietary methyl factors examined.

8. analysis of AKT (show AKT1 Proteins) signaling pathway activated by HIN-1 (show OTUD4 Proteins) methylation in non-small cell lung cancer

9. Data show that SCGB3A1 was down-regulated in invasive compared with DCIS, whereas talin 2 (TLN2 (show TLN2 Proteins)) and PTGS1 (show PTGS1 Proteins) were up-regulated in invasive compared with DCIS.

10. Data suggest that high methylation of the HIN-1 (show OTUD4 Proteins) promoter results in silenced HIN-1 (show OTUD4 Proteins) expression in gastric cancer, and that 5-aza-2'-deoxycytidine reverses HIN-1 (show OTUD4 Proteins) methylation and reduces viability of gastric cancer cells.

Mouse (Murine) Secretoglobin, Family 3A, Member 1 (SCGB3A1) interaction partners

1. Neonatal hyperoxia followed by RA recovery was associated with decreased lung CCSP and SCGB3A1 protein but not mRNA expression.

2. The differential expression of mRNA by both airway level and lung region was determined for uteroglobin-related protein 2.

3. Highest HIN-1 and UGRP-1 (show SCGB3A2 Proteins) expression is detected in the lung, while lower level HIN-1 expression is also detected in the stomach, heart, small intestine, uterine and mammary glands

4. genomic structure and expression patterns of Ugrp2 and its alternative spliced form were characterized

5. EGF (show EGF Proteins)-induced increase of Ugrp2 occurred at the transcriptional level that required the EGF receptor (show EGFR Proteins) and the activation of the ERK-MAPK (show MAPK1 Proteins) and phosphoinositide-3 kinase pathways

6. ubiquitous transcription factor NF-Y binds to and activates expression of the Scgb3a1 gene and tissue-specific expression of the gene is associated with CpG methylation of the promoter

7. The expression of SCGB3A1 and SCGB3A2 (show SCGB3A2 Proteins) are bidirectionally regulated by oncostatin M (OSM (show OSM Proteins)) when examined in a mouse transformed Clara cell line.

8. Expression of SCGB3A1 was down-regulated by IFN-gamma (show IFNG Proteins) in a time- and dose-dependent manner in the murine transformed Clara Cells line.