anti-Secretogranin III (SCG3) Antibodies

The protein encoded by SCG3 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Additionally we are shipping Secretogranin III Kits (19) and Secretogranin III Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCG3 29106 Q8WXD2
SCG3 20255 P47867
SCG3 116635 P47868
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Top anti-Secretogranin III Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SCG3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-SCG3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using SCG3 antibody. Immunohistochemistry of paraffin-embedded human gastric using SCG3 antibody at dilution of 1:100 (x40 lens). 100 μL 11 to 13 Days
$366.77
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of HeLa cells, using Secretogranin III antibody. ABIN6273160 at 1/100 staining Human kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Immunohistochemical analysis of paraffin-embedded rat tissue sections (brain), staining SCDG3 in cytoplasm, DAB chromogenic reaction 0.1 mg 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC, IHC (fro), IHC (p), WB 100 μg 11 to 14 Days
$449.17
Details
Horse Rabbit Un-conjugated IHC, IHC (p), WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated WB SCG3 Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SCG3 antibody detected the SCG3 protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), WB Anti-Secretogranin 3 antibody, Western blotting WB: HELA Cell Lysate Anti-Secretogranin 3 antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg 4 to 6 Days
$280.00
Details

Top referenced anti-Secretogranin III Antibodies

  1. Human Polyclonal SCG3 Primary Antibody for IHC (p), WB - ABIN548555 : Tanabe, Yanagiya, Iida, Saito, Sekine, Takahashi, Nakamura, Tsunoda, Kamohara, Nakata, Kotani, Komatsu, Itoh, Mineo, Wada, Funahashi, Miyazaki, Tokunaga, Hamaguchi, Shimada, Tanaka, Yamada, Hanafusa et al.: Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity. ... in The Journal of clinical endocrinology and metabolism 2007 (PubMed)

  2. Human Polyclonal SCG3 Primary Antibody for IHC, IHC (p) - ABIN4352445 : Leja, Essaghir, Essand, Wester, Oberg, Tötterman, Lloyd, Vasmatzis, Demoulin, Giandomenico: Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 (PubMed)

More Antibodies against Secretogranin III Interaction Partners

Human Secretogranin III (SCG3) interaction partners

  1. SCG3 may be involved in PQinduced astrocyte activation via regulation of the expression and selective recruitment of cellular factors, thus suggesting that SCG3 may represent an indicator of astrocyte activation.

  2. This review summarizes our current knowledge of Scg3 as a regulatory protein of secretory granules, highlights its new role as a highly disease-selective angiogenic factor, and envisions Scg3 inhibitors as "selective angiogenesis blockers" for targeted therapy of diabetic retinopathy. [review]

  3. results suggested an association between the fucosylated glycoform of short-form SgIII and Small Cell Lung Carcinoma

  4. HBXIP facilitates the proliferation of hepatoma cells by up-regulating SCG3 via E2F1 and miR-509-3p modulation.

  5. SCG3 is essential in the process and targeting of neuropeptides and neurotrophins, its participation in the pathological progression of Alzheimer's disease may be suggested

  6. SCG3 may be involved in apoptosis signal transduction as a caspase substrate.It may be a pivotal component of the neuroendocrine pathway & play an important role in neuronal communication & neurotransmitter release.

  7. Our data suggest that genetic variations in the FTO, SCG3 and MTMR9 genes independently influence the risk of metabolic syndrome.

  8. This short review deals with investigations in neuroendocrine tumors (NETs) with antibodies against defined epitopes of chromogranins (Cgs) A and B and secretogranins (Sgs) II and III.

  9. SgIII was expressed in 41 of 47 neuroendocrine tumours. The expression of SgIII agreed well with that of CgA, CgB and SgII, with exceptions of phaeochromocytomas and parathyroid adenomas.

  10. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion.

  11. Secretogranins III assays failed to detect increased concentrations in any of the patients with neuroendocrine tumours.

  12. these data suggest that SgIII, DMT-1 and HNP-1 are implicated in cell-mediated LDL oxidation.

Mouse (Murine) Secretogranin III (SCG3) interaction partners

  1. This review summarizes our current knowledge of Scg3 as a regulatory protein of secretory granules, highlights its new role as a highly disease-selective angiogenic factor, and envisions Scg3 inhibitors as "selective angiogenesis blockers" for targeted therapy of diabetic retinopathy.[ review]

  2. we show by RNA silencing that CPE and SgIII play a synergistic role in the trafficking of POMC to granules of the regulated secretory pathway in AtT20 cells

  3. SgIII knockdown impairs intracellular retention of chromogranin A and proopiomelanocortin in AtT-20 cells.

  4. The robust expression of SgIII in astrocytes and its regulation in the injured brain suggest both intracellular and extracellular roles for this glial granin in the physiology and repair/damage of neuronal circuits.

  5. SgIII directly binds to cholesterol components of the secretory granule membrane and targets chromogranin A to secretory granules in pituitary and pancreatic endocrine cells

  6. SgIII and CPE form the separate functional sorting complex by anchoring to cholesterol-rich SG membranes, and POMC-derived peptides are transferred from CPE to SgIII, and subsequently to CgA.

  7. SCG2, as well as SCG3, may be a potential regulator of food intake based on its capacity to accumulate appetite-related hormones into secretory granules.

Secretogranin III (SCG3) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones\; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SCG3

  • secretogranin III L homeolog (scg3.L) antibody
  • secretogranin III (scg3) antibody
  • secretogranin III (SCG3) antibody
  • secretogranin III (Scg3) antibody
  • 1B1075 antibody
  • AI385542 antibody
  • Chgd antibody
  • DKFZp459J1919 antibody
  • scg3-A antibody
  • SGIII antibody
  • zgc:73236 antibody

Protein level used designations for SCG3

secretogranin III , secretogranin-3 , secretogranin-3-like , 1B1075

GENE ID SPECIES
373575 Xenopus laevis
393730 Danio rerio
415424 Gallus gallus
453437 Pan troglodytes
478307 Canis lupus familiaris
694089 Macaca mulatta
100055140 Equus caballus
100125084 Xenopus (Silurana) tropicalis
100154760 Sus scrofa
100173578 Pongo abelii
100343331 Oryctolagus cuniculus
100412626 Callithrix jacchus
100465413 Ailuropoda melanoleuca
29106 Homo sapiens
20255 Mus musculus
116635 Rattus norvegicus
525941 Bos taurus
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