Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) ELISA Kits

SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Additionally we are shipping SELP Antibodies (391) and SELP Proteins (39) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SELP 25651 P98106
SELP 6403 P16109
SELP 20344 Q01102
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Top SELP ELISA Kits at antibodies-online.com

Showing 10 out of 133 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 5pg/mL 62.5-4000 pg/mL Human P-Selectin PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$300.00
Details
Rat 2.34 ng/mL 9.38-600 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$812.78
Details
Mouse 5pg/mL 62.5-4000 pg/mL Mouse P-Selectin PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$320.00
Details
Pig 2.73 ng/mL 6.25 ng/mL - 400 ng/mL 96 Tests Log in to see 13 to 16 Days
$795.79
Details
Rabbit 0.6 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Log in to see 13 to 16 Days
$720.00
Details
Dog 3.12 ng/mL 12.5-800 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$788.33
Details
Cow 0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Sheep 3.13 ng/mL n/a   96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Pig 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 1.0 ng/mL 25-500 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced SELP ELISA Kits

  1. Rat (Rattus) SELP ELISA Kit for Sandwich ELISA - ABIN365567 : Yang, Zhu, Zhao, Wu, Wang, Wang, Zheng, Chen, Liu, Peng: The application of tetrahydroisoquinoline-3-carbonyl-TARGD(F)F as an anti-thrombotic agent having dual mechanisms of action. in Molecular bioSystems 2012 (PubMed)
    Show all 5 Pubmed References

  2. Human SELP ELISA Kit for Sandwich ELISA - ABIN411351 : Florian, Schlüter, Bohnensack: A new member of the sorting nexin family interacts with the C-terminus of P-selectin. in Biochemical and biophysical research communications 2001 (PubMed)
    Show all 7 Pubmed References

  3. Mouse (Murine) SELP ELISA Kit for Sandwich ELISA - ABIN411352 : Zhong, He, Yang, Bao, Zhang, Zhou, Chen, Li, Han, Yang, Sun, Cao, Li, Shi, Jiang, Zhang, Yan: L-selectin and P-selectin are novel biomarkers of cervicovaginal inflammation for preclinical mucosal safety assessment of anti-HIV-1 microbicide. in Antimicrobial agents and chemotherapy 2012 (PubMed)
    Show all 7 Pubmed References

  4. Human SELP ELISA Kit for Sandwich ELISA - ABIN417375 : Hoetzenecker, Assinger, Lichtenauer, Mildner, Schweiger, Starlinger, Jakab, Berényi, Pavo, Zimmermann, Gabriel, Plass, Gyöngyösi, Volf, Ankersmit et al.: Secretome of apoptotic peripheral blood cells (APOSEC) attenuates microvascular obstruction in a porcine closed chest reperfused acute myocardial infarction model: role of platelet aggregation and ... in Basic research in cardiology 2012 (PubMed)
    Show all 4 Pubmed References

  5. Mouse (Murine) SELP ELISA Kit for Sandwich ELISA - ABIN365472 : Rozalski, Kassassir, Siewiera, Klepacka, Sychowski, Watala: Platelet activation patterns are different in mouse models of diabetes and chronic inhibition of nitric oxide synthesis. in Thrombosis research 2014 (PubMed)
    Show all 3 Pubmed References

  6. Human SELP ELISA Kit for Sandwich ELISA - ABIN1979403 : Thasneem, Sajeesh, Sharma: Glucosylated polymeric nanoparticles: a sweetened approach against blood compatibility paradox. in Colloids and surfaces. B, Biointerfaces 2013 (PubMed)
    Show all 3 Pubmed References

  7. Human SELP ELISA Kit for Sandwich ELISA - ABIN2685451 : Burger, Wagner: Platelet P-selectin facilitates atherosclerotic lesion development. in Blood 2003 (PubMed)
    Show all 3 Pubmed References

  8. Pig (Porcine) SELP ELISA Kit for Sandwich ELISA - ABIN415867 : Tang, Liu, Wu, Chen, Jin, Gao, Zhu, Shen: Effect of hirulog-like peptide on balloon catheter injury-induced neointimal formation in femoral arteries of minipigs and relationship with inflammatory mediators. in Journal of vascular research 2010 (PubMed)
    Show all 2 Pubmed References

  9. Rat (Rattus) SELP ELISA Kit for Sandwich ELISA - ABIN416270 : Xu, Yu, Lin, Tan, Bai, Ding, Li: Chemical sympathectomy attenuates inflammation, glycocalyx shedding and coagulation disorders in rats with acute traumatic coagulopathy. in Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2015 (PubMed)
    Show all 2 Pubmed References

  10. Human SELP ELISA Kit for Sandwich ELISA - ABIN1117048 : Yuan, Chen, Ding, Liu, Wu, Lin, Shen, Gai: Copolymer coatings consisting of 2-methacryloyloxyethyl phosphorylcholine and 3-methacryloxypropyl trimethoxysilane via ATRP to improve cellulose biocompatibility. in ACS applied materials & interfaces 2012 (PubMed)

More ELISA Kits for SELP Interaction Partners

Human Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. P-selectin may indicate thrombotic risk assessment in atrial fibrillation

  2. results found that P-selectin-induced elevations of p-p38 and p-PI3K levels were significantly inhibited by hsa-miR-370, indicating that repressed sLe(x) level is able to reduce the P-selectin binding and therefore eliminating the P-selectin-induced activation of p38 and PI3K signaling.

  3. In young adults from the general population, circulating P-selectin and E-selectin levels appear positively related to CMR-derived aortic wall thickness and PWV, possibly pointing towards atherogenic inflammatory arterial wall alterations.

  4. polymorphisms of SELP have shown significant association with sP-selectin levels as well as vascular risk in T2DM patients

  5. There is a direct correlation between p-selectin level and severe blood stasis in the left atrium.

  6. Suggest role for soluble P-selectin in the diagnosis of venous thromboembolism.

  7. Levels of E and P selectin showed positive correlation with the length of stay.

  8. plasma level predictive of high residual platelet reactivity during maintenance-phase dual antiplatelet therapy

  9. Kidney transplant has a significant restorative effect on platelet aggregation and coagulation functions independent of platelet activation, as evaluated with P-selectin levels.

  10. In Chinese Han population cardiovascular disease (CVD) risk is significantly higher in carriers with rs1800805-A allele (GA and AA) in the selectin P gene (SELP) than those with GG genotype. CVD risk is the highest for rs1800805-GA or AA carriers with additional genetic polymorphisms 1800796-GC or CC in interleukin 6 gene.

  11. VWF, GMP-140, ADAMTS13 and the cerebral vasospasm, delayed cerebral ischemia, tumor diameter and prognosis of aneurysmal subarachnoid hemorrhage patients are closely related

  12. The highest level of sP-selectin in colorectal patients was observed in patients with metastases to the liver (stage IV), and was significantly higher than in patients without metastases (stage I/II) and with lymph node metastases (stage III), p = .02. P-selectin plays an important role in the progression of CRC

  13. Serum P-selectin levels are not altered in cystic fibrosis patients.

  14. miR-223, miR-26b, miR-126 and miR-140 are expressed at a lower level in platelets and megakaryocytes in type 2 diabetics causing up-regulation of P2RY12 and SELP mRNAs that may contribute to adverse platelet function.

  15. coronary thrombi in STEMI patients resistant to fibrinolysis are characterised by higher fibrin, P-selectin and VWF content than lysis-sensitive thrombi

  16. P-Selectin and ICAM-1 have roles in mediating THP-1 monocyte adhesion

  17. Transgenic expression of SELP is atherogenic in Apoe(-/-) mice, suggesting that P-selectin contributes to atherogenesis.

  18. These results provide a novel insight into the mechano-chemical regulation mechanism for P-selectin-induced calcium signaling of neutrophils in flow.

  19. Data indicate no association of maternal or fetal ITGA2 C807T SNP, ITGB3 T1565C SNP, PECAM1 CTG - GTG and SELP A/C polymorphisms with fetal growth restriction (FGR).

  20. Study concluded that the genotype and allele frequencies of SELP S290N were not significant different between the acute ischemic stroke case group and the control group as well as between each subtype group and the control group

Horse (Equine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. Despite the decrease of CD62P expression, the observed increased surface expression of CD41/61 on platelets in horses with recurrent airway obstruction may contribute to the formation of platelet aggregates in their respiratory system.

Cow (Bovine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. Five single nucleotide polymorphisms (SNPs) from different exons in selectin SELP, two in selectin SELL and one in selectin SELE were taken forward to genotyping in 337 Holstein Friesian heifers using PCR-RFLP.

  2. SELP mediates the attachment of peripheral blood leukocytes to endothelium and provides novel evidence that its high polymorphism is likely to affect biological function. This may potentially influence leukocyte migration and fertility, both key to successful performance in dairy cows.

Mouse (Murine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. Choroid plexus endothelial cells are conventionally polarized, but express P-cadherin at cell-cell contacts, and Lgl2 and syntaxin-4 in the luminal plasma membrane domain.

  2. Platelet Ral GTPases primarily control P-selectin surface expression, in turn regulating platelet-leukocyte interaction.

  3. In a laser injury-induced thrombosis model, P-selectin modulates thrombus propagation independently of VWF and TSP1

  4. deletion of P-sel disrupted megakaryocyte/neutrophil interactions in spleen, reduced TGF-beta content, and corrected the hematopoietic stem cells distribution that in Gata1(low) mice, as in primary myelofibrosis patients, is abnormally expanded in spleen.

  5. The present study supported the notion that CD62P accumulation during platelet storage is involved in mediating transfusion-related acute lung injury.

  6. Holothurian glycosaminoglycan has emerged as a novel anti-cancer agent via blocking P-selectin-mediated malignant events of tumor metastasis.

  7. Data (including data from studies in transgenic mice) suggest that sequence variations limited to 1.4-kb proximal promoter region account for most differences in expression of murine Selp and human SELP genes.

  8. P-selectin has a role in endothelial progenitor cells' inhibition of platelet function

  9. Both platelet and endothelial cell P-selectin contribute to host defense during Klebsiella pneumosepsis.

  10. Platelet infiltration into solid tumors occurs through a P-selectin-dependent mechanism and promotes tumor growth.

  11. P-selectin promotes neutrophil extracellular trap (NET) formation and is a potential target for NET-related diseases.

  12. P-selectin is an important adhesion molecule vital for infiltration of regulatory T cells into mouse mammary tumors

  13. Administering human recombinant PTX3 to wild-type mice induced endothelial dysfunction and increased blood pressure, an effect absent in P-selectin-deficient mice.

  14. Targeting P-selectin-mediated platelet adhesion onto endometriotic lesions holds promise as a novel therapeutics for treating endometriosis.

  15. Endothelial peroxisome proliferator-activated receptor-gamma protects against thrombosis through a mechanism that involves downregulation of P-selectin expression and diminished P-selectin-mediated leukocyte-endothelial interactions.

  16. involved in neutrophil recruitment into the kidney after induction of sepsis

  17. Regulatory T cells dynamically regulate P and E selectin ligand expression during multiple challenge contact hypersensitivity.

  18. These results demonstrate that chronically raised sP-selectin favours progression of an unstable atherosclerotic plaque phenotype.

  19. P-selectin-mediated platelet adhesion promotes the metastasis of murine melanoma cells.

  20. In the absence of either PSGL-1 or E- and P-selectin.

SELP Antigen Profile

Antigen Summary

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Gene names and symbols associated with SELP

  • selectin P (Selp) antibody
  • selectin P (SELP) antibody
  • selectin, platelet (Selp) antibody
  • CD62 antibody
  • CD62P antibody
  • GMP-140 antibody
  • GMP140 antibody
  • Grmp antibody
  • LECAM3 antibody
  • PADGEM antibody
  • PSEL antibody
  • PSELECT antibody

Protein level used designations for SELP

CD62 antigen-like family member P , GMP-140 , LECAM3 , P-selectin , PADGEM , granule membrane protein 140 , leukocyte-endothelial cell adhesion molecule 3 , platelet activation dependent granule-external membrane protein , selectin, platelet , granulocyte membrane protein , platelet alpha-granule membrane protein , CD62P antigen , cell adhesion molecule

GENE ID SPECIES
25651 Rattus norvegicus
6403 Homo sapiens
100009695 Equus caballus
443305 Ovis aries
397150 Sus scrofa
100009534 Oryctolagus cuniculus
100716162 Cavia porcellus
281486 Bos taurus
403994 Canis lupus familiaris
424364 Gallus gallus
20344 Mus musculus
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