anti-Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) Antibodies

Binds to plexin family members and plays an important role in the regulation of developmental processes. Additionally we are shipping SEMA3C Kits (16) and SEMA3C Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SEMA3C 10512 Q99985
SEMA3C 20348 Q62181
SEMA3C 296787  
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Top anti-SEMA3C Antibodies at

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of SEMA3C Antibody (C-term) (ABIN651266) in mouse lung tissue lysates (35 µg/lane).SEMA3C (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis SEMA3C using Jurkat whole cell lysates ABIN6278525 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 15 to 18 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin mouse intestine tissue labeled withAnti-Sema3C/Semaphorin 3c Polyclonal Antibody, Unconjugated (ABIN720026) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see Available
Human Rabbit Un-conjugated IHC, ELISA   100 μg Log in to see 2 to 3 Days
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using SEMA3C antibody. 200 μL Log in to see 12 to 14 Days
Human Rabbit Un-conjugated WB   100 μL Log in to see 11 to 14 Days
Human Rabbit Un-conjugated IHC, IHC (p)   100 μL Log in to see 11 to 14 Days

Top referenced anti-SEMA3C Antibodies

  1. Human Polyclonal SEMA3C Primary Antibody for WB - ABIN651266 : Esselens, Malapeira, Colomé, Casal, Rodríguez-Manzaneque, Canals, Arribas: The cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migration. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 Pubmed References

More Antibodies against SEMA3C Interaction Partners

Human Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) interaction partners

  1. we show that SEMA3C promotes migration and invasion in vitro and cell dissemination in vivo.

  2. Study provide the first evidence that SEMA3C, SEMA5A and SEMA6D can be considered as markers of liver injury in chronic hepatitis C. While serum concentrations of SEMA3C and SEMA6D significantly increased with fibrosis stage in both HCV-g1 and HCV-g3 infections, the concentration of SEMA5A inversely correlated with fibrosis stage in both HCV genotypes.

  3. in situ hybridization analysis revealed that Sema 3C and Sema 3F are expressed at the RNA level in the endometriosis affected peritoneum

  4. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner in prostate tumor cells.

  5. The exploratory genome-wide association studies confirmed APOE and identified the novel loci: rs2525776 near SEMA3C (P = 1 x 10(-8), OR = 3.3 [2.1-5.1]).

  6. Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway.

  7. FR-sema3C could perhaps be used for the treatment of AMD.

  8. SEMA3C plays a role in the progression of breast cancer and may positively influence breast cancer cell adhesion, invasion and proliferation, as well as being associated with grade of disease and estrogen receptor status.

  9. Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.

  10. Increased levels of Sema3C protein may be associated with the progression of glioma tumor and have potential as a prognostic marker for outcome of glioma patients.

  11. SEMA3C expression increased in the transition from normal to malignant breast lesions and correlated with microvessel density and tumour grade and is differentially regulated in the development of breast versus oral neoplasia.

  12. Glioma stem cells preferentially secrete Sema3C and coordinately express PlexinA2/D1 receptors to activate Rac1/nuclear factor (NF)-kB signaling.

  13. p65-Sema3C, but not FR-sema3C, rendered A549 lung cancer cells resistant to serum deprivation, suggesting that previously reported protumorigenic activities of sema3C may be due to p65-Sema3C produced by tumor cells

  14. Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

  15. SEMA3C is a novel adipokine regulated by weight changes.

  16. Capillary-like tubular formation was reduced by the addition of culture media of sema3C miRNA cells.

  17. The role of the motoneuronal Sema3 code could be to set population-specific axon sensitivity to limb-derived chemotropic Sema3 proteins, therefore specifying stereotyped motor nerve trajectories in their target field.

  18. cleavage of semaphorin 3C induced by ADAMTS1 promotes the migration of breast cancer cells, indicating that the co-expression of these molecules in tumors may contribute to the metastatic program

  19. correlation of gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients

  20. human glioma cells express class 3 semaphorins and receptors for soluble and membrane-bound semaphorins, suggesting a possible role of the semaphorin/neuropilin system in the interactions of human malignant glioma with the nervous and immune systems.

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) interaction partners

  1. Sema3c is a candidate that mediates interaction between cardiac neural crest cells and the second heart field during development of the outflow tract.

  2. analyzed a complementary set of ligand-specific and tissue-specific mutants to show that neural crest-derived SEMA3C activates NRP1 in the cardiac outflow tract endothelium

  3. Sema3A overrides the effects of Sema3C in cortical axons exposed to defined mixtures of these opposing guidance cues in vitro

  4. No changes were observed in the binding of Sema3C to Nrp1-silenced B16(F10) cells, nor in its chemorepellent activity.

  5. Data suggest that the formation and synaptic specificity of the GABAergic septohippocampal pathway relies on robust molecular mechanisms, independent of semaphorin 3C.

  6. the guidance factor Semaphorin 3C, which is expressed by corpus callosum neurons, acts through the neuropilin 1 receptor to orient axons crossing through the corpus callosum.

  7. Secreted sema3C favors cell survival and neuritogenesis of cultured cerebellar granule neurons

  8. GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis

  9. sema 3C promotes glomerular endothelial cell proliferation, adhesion, directional migration, and tube formation in vitro by stimulating integrin phosphorylation and VEGF120 secretion

  10. Taken together, our results reveal a molecular interaction between MMPs and semaphorins providing new insight into the molecular mechanism allowing axonal growth cone to respond to environmental guidance cues in the context of cortical development.

  11. Npn1-dependent morphogenesis is mediated by Sema3A and Sema3C in an additive manner.

  12. The endocytic pathway of neuropilin(Nrp)1 depends on its ligand: sema3C induces lipid raft-dependent endocytosis.

  13. mutations in GATA6 are genetic causes of congenital heart diseases involving outflow tract defects, as a result of the disruption of the direct regulation of semaphorin 3C-plexin A2 signaling

SEMA3C Antigen Profile

Protein Summary

Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).

Gene names and symbols associated with SEMA3C

  • semaphorin 3C (SEMA3C) antibody
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (Sema3c) antibody
  • semaphorin 3C (Sema3c) antibody
  • 1110036B02Rik antibody
  • Semae antibody
  • SemE antibody

Protein level used designations for SEMA3C

sema E , semaphorin E , semaphorin-3C , semaphorin-E , COLL-3 , collapsin-3

100054706 Equus caballus
10512 Homo sapiens
20348 Mus musculus
374090 Gallus gallus
512660 Bos taurus
296787 Rattus norvegicus
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