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Binds to plexin family members and plays an important role in the regulation of developmental processes. Additionally we are shipping SEMA3C Antibodies (77) and SEMA3C Proteins (9) and many more products for this protein.
Showing 4 out of 15 products:
Human SEMA3C ELISA Kit for Sandwich ELISA - ABIN572402
Scheerer, Frangini, Chiantera, Mechsner: Reduced Sympathetic Innervation in Endometriosis is Associated to Semaphorin 3C and 3F Expression. in Molecular neurobiology 2016
in situ hybridization analysis revealed that Sema (show SEMA3B ELISA Kits) 3C and Sema (show SEMA3B ELISA Kits) 3F are expressed at the RNA level in the endometriosis affected peritoneum
Androgen receptor (show AR ELISA Kits) transcriptionally regulates semaphorin 3C in a GATA2 (show GATA2 ELISA Kits)-dependent manner in prostate tumor cells.
The exploratory genome-wide association studies confirmed APOE (show APOE ELISA Kits) and identified the novel loci: rs2525776 near SEMA3C (P = 1 x 10(-8), OR = 3.3 [2.1-5.1]).
Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 (show MAPK1/3 ELISA Kits) signaling pathway.
FR-sema3C could perhaps be used for the treatment of AMD (show AMD1 ELISA Kits).
SEMA3C plays a role in the progression of breast cancer and may positively influence breast cancer cell adhesion, invasion and proliferation, as well as being associated with grade of disease and estrogen receptor (show ESR1 ELISA Kits) status.
Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 (show NRP2 ELISA Kits) in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.
Increased levels of Sema3C protein may be associated with the progression of glioma tumor and have potential as a prognostic marker for outcome of glioma patients.
SEMA3C expression increased in the transition from normal to malignant breast lesions and correlated with microvessel density and tumour grade and is differentially regulated in the development of breast versus oral neoplasia.
Glioma stem cells preferentially secrete Sema3C and coordinately express PlexinA2/D1 receptors to activate Rac1 (show RAC1 ELISA Kits)/nuclear factor (NF)-kB signaling.
analyzed a complementary set of ligand-specific and tissue-specific mutants to show that neural crest-derived SEMA3C activates NRP1 (show NRP1 ELISA Kits) in the cardiac outflow tract endothelium
Sema3A (show SEMA3A ELISA Kits) overrides the effects of Sema3C in cortical axons exposed to defined mixtures of these opposing guidance cues in vitro
No changes were observed in the binding of Sema3C to Nrp1 (show NRP1 ELISA Kits)-silenced B16(F10 (show F10 ELISA Kits)) cells, nor in its chemorepellent activity.
Data suggest that the formation and synaptic specificity of the GABAergic septohippocampal pathway relies on robust molecular mechanisms, independent of semaphorin 3C.
the guidance factor Semaphorin 3C, which is expressed by corpus callosum neurons, acts through the neuropilin 1 (show NRP1 ELISA Kits) receptor to orient axons crossing through the corpus callosum.
Secreted sema3C favors cell survival and neuritogenesis of cultured cerebellar granule neurons
GATA-6 (show GATA6 ELISA Kits) regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis
sema (show SEMA3B ELISA Kits) 3C promotes glomerular endothelial cell proliferation, adhesion, directional migration, and tube formation in vitro by stimulating integrin phosphorylation and VEGF120 (show VEGFA ELISA Kits) secretion
Npn1 (show NRP1 ELISA Kits)-dependent morphogenesis is mediated by Sema3A (show SEMA3A ELISA Kits) and Sema3C in an additive manner.
The endocytic pathway of neuropilin(Nrp)1 (show NRP1 ELISA Kits) depends on its ligand: sema3C induces lipid raft-dependent endocytosis.
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
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