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Has chemorepulsive activities for sympathetic axons. Additionally we are shipping SEMA3G Antibodies (31) and SEMA3G Proteins (3) and many more products for this protein.
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Results indicate that Sema3G protein is secreted by podocytes and protects them from inflammatory kidney diseases and diabetic nephropathy.
Results identify Sema3g as one of the downstream effectors of PPAR-gamma, which is centrally involved in regulating endothelial cell migration.
overexpressed SEMA3G inhibited the migratory and invasive behavior of U251MG cancer cells
Identify Sema3G as a primarily endothelial cell-expressed class 3 semaphorin that controls endothelial and smooth muscle cell functions in autocrine and paracrine manners.
In gliomas, SEMA3B, SEMA3G and NRP2 expressions were related to prolonged survival
Sema3G inhibits tumor progression from MDA-MB-435 but not from MDA-MB-231 cancer cells. It inhibits tumor angiogenesis in MDA-MB-231 cells.
Sema3G induces cell collapse in an Nrp2/PlexinD1-dependent manner.
In adulthood, Sema3G is mainly expressed in the lung and kidney, and a little in the brain. We also found that Sema3G binds Neuropilin-2, but not Neuropilin-1, and induces the repulsion of sympathetic axons.
Has chemorepulsive activities for sympathetic axons. Ligand of NRP2.
, Semaphorin 3G
, semaphorin 3G
, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G