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Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additionally we are shipping SEMA4G Antibodies (16) and SEMA4G Kits (2) and many more products for this protein.
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These findings provide evidence that the miR (show MLXIP Proteins)-608 rs4919510 polymorphism may modify cancer susceptibility in a type-specific manner. Furthermore, SEMA4G may function as an oncogene (show RAB1A Proteins) or tumour suppressor to regulate tumour development in a type-specific manner. Further studies with experimental evaluations are warranted.
We have identified here Sema4C (show SEMA4C Proteins) and Sema4G as candidate ligands for Plexin-B2 (show PLXNB2 Proteins)
Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
, semaphorin 4G
, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G