Semenogelin I Proteins (SEMG1)

The protein encoded by SEMG1 is the predominant protein in semen. Additionally we are shipping Semenogelin I Antibodies (65) and Semenogelin I Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEMG1 6406 P04279
SEMG1 25013  
Mouse SEMG1 SEMG1 53878  
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Top Semenogelin I Proteins at

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Human Cells Human His tag   50 μg Log in to see 4 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 13 to 16 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Human Cells Human His tag   10 μg Log in to see 15 to 16 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
HEK-293 Cells Human His tag   10 μg Log in to see 4 to 8 Days
Escherichia coli (E. coli) Human S tag,His tag 100 μg Log in to see 15 to 18 Days

SEMG1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus)

More Proteins for Semenogelin I (SEMG1) Interaction Partners

Human Semenogelin I (SEMG1) interaction partners

  1. Data indicate that semenogelin I (Sg I) expression has potential value in predicting renal cell carcinoma (RCC) progression and prognosis, suggesting the use of Sg I as a biomarker for RCC.

  2. Peptides from the antimicrobial protein semenogelin I have antibacterial activity.

  3. EPPIN and SEMG1 rapidly co-evolved in primates

  4. SEMG1 was significantly changed in asthenozoosperm, which could be the candidate gene for the development of diagnostic marker and provided the opportunity to further illustrate the biological mechanisms of asthenozoospermia.

  5. Three regions of SEM1(86-107) comprise the amyloid fibril core that enhances HIV-1 infection.

  6. Interaction analysis identifies semenogelin I fragments as new binding partners of PIP in human seminal plasma

  7. EPPIN's semenogelin I binding site: a contraceptive drug target.

  8. Nuclear semenogelin I expression could be a reliable prognosticator in men who undergo radical prostatectomy.

  9. The proteomes of the type-1 diabetic, type-2 diabetic, and non-diabetic obese patients presented elevated amounts of the same set of one molecular form of semenogelin-1, one form of clusterin, and two forms of lactotransferrin.

  10. Peptides released by physiological cleavage of Semg1 and Semg2 form amyloids that enhance HIV infection.

  11. These results suggest the involvement of semenogelins in prostate cancer and their prognostic values in predicting cancer progression after radical prostatectomy.

  12. Spermatozoa interact with semenogelin I in solution in a non-Zn2+-dependent manner, but associate with immobilized semenogelin I only in the presence of Zn2+.

  13. Cysteine 239 of rSEMG1 appears to be the critical amino acid for both binding to eppin and inhibiting sperm motility.

  14. Transcripts in the gastro-intestinal tract and skeletal muscle almost exclusively encoded SgI

  15. Seminal plasma motility inhibitor, one of the fragments of Sg, has its inhibitory effect on ejaculated spermatozoa in liquefied semen under physiological conditions.

  16. peptides produced by cleavage of semenogelin I, the predominant human semen coagulum protein, had high levels of antibacterial activity.

  17. structural changes in the semenogelin 1 and 2 proteins that have arisen since the human-chimpanzee-gorilla split may be responsible for the physiological differences between these species ejaculated semen that correlate with their sociosexual behavior

  18. The binding of Zn2+ to SgI and SgII and their involvment in regulating the activity of PSA are reported.

  19. in seminal plasma and on spermatozoa following ejaculation, Eppin is bound to semenogelin I

  20. Authors analyzed an intronic T9 repeat of semenogelin I (SEMG1) and report mutation frequencies of 51% (75 of 146) and 62% (8 of 13) in MMR-deficient primary colorectal cancers and cell lines, respectively.

Mouse (Murine) Semenogelin I (SEMG1) interaction partners

  1. SVS2 keeps sterols on the sperm plasma membrane and plays a key role in unlocking sperm capacitation in vivo.

  2. Seminal vesicle protein SVS2 is required for sperm survival in the uterus.

  3. the fertility of ejaculated sperm is associated with SVS2 distribution in the female reproductive tract, SVS2 functions as a decapacitation factor for mouse sperm.

Semenogelin I (SEMG1) Protein Profile

Protein Summary

The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.

Gene names and symbols associated with Semenogelin I Proteins (SEMG1)

  • semenogelin II (SEMG2)
  • semenogelin I (SEMG1)
  • semenogelin-2 (LOC100408385)
  • semenogelin I (Semg1)
  • seminal vesicle secretory protein 2 (Svs2)
  • BB115391 protein
  • CT103 protein
  • dJ172H20.2 protein
  • RATSVPIIA protein
  • SEMG protein
  • Semg1 protein
  • SEMG1a protein
  • SGI protein
  • Svp1 protein
  • SVPIIA protein
  • Svs2 protein
  • SVS2P protein
  • Svs2p2 protein
  • SvsII protein

Protein level used designations for Semenogelin I Proteins (SEMG1)

semenogelin I , semenogelin 1 , semenogelin-1-like , semenogelin I isoform a preproprotein , cancer/testis antigen 103 , semen coagulating protein , semenogelin-1 , SVS II , seminal vesicle protein, secretion 1 , seminal vesicle protein, secretion 2 , seminal vesicle secretory protein 2 , seminal vesicle secretory protein II , semenoclotin

458277 Pan troglodytes
711402 Macaca mulatta
100408385 Callithrix jacchus
6406 Homo sapiens
25013 Rattus norvegicus
53878 Mus musculus
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