Septin 6 Proteins (SEPT6)

SEPT6 is a member of the septin family of GTPases. Additionally we are shipping Septin 6 Antibodies (74) and Septin 6 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEPT6 23157 Q14141
SEPT6 56526 Q9R1T4
SEPT6 691335  
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Top Septin 6 Proteins at

Showing 7 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human His tag   100 μg Log in to see 2 to 3 Days
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days

SEPT6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,

Rat (Rattus)

More Proteins for Septin 6 (SEPT6) Interaction Partners

Fruit Fly (Drosophila melanogaster) Septin 6 (SEPT6) interaction partners

  1. It has been found that Sep2 is uniquely required for follicle cell encapsulation of female germline cysts, and that Sep2 and Sep5 are redundant for follicle cell proliferation.

  2. Results show that Sep2 Sep5 double mutants have an early pupal lethal phenotype and lack imaginal discs, suggesting that these genes have redundant functions during imaginal cell proliferation.

Zebrafish Septin 6 (SEPT6) interaction partners

  1. Sept6 is first expressed in the notochord and then in nearly all of the ciliary organs, including Kupffer's vesicle (KV), the pronephros, eye, olfactory bulb, and neural tube. Knockdown of sept6 results in reduced numbers and length of cilia in KV.

Human Septin 6 (SEPT6) interaction partners

  1. SUMOylation of human septins is critical for septin filament bundling and cytokinesis.

  2. MiR (show MLXIP Proteins)-223-3p might target gene SEPT6 and promoted the biological behavior of prostate cancer.

  3. Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis

  4. The SEPT6 provides the directional guidance cues necessary for polarizing the epithelial microtubule network.

  5. Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 (show SEPT2 Proteins) group, SEPT3 (show SEPT3 Proteins) group and SEPT7 (show SEPT7 Proteins) group.

  6. MLL (show MLL Proteins)-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia

  7. Molecular analysis using rtPCR followed by sequencing confirmed the expression of an MLL (show MLL Proteins)-SEPT6 fusion transcript with a novel sequence.

  8. septin 2 (show SEPT2 Proteins), 6, and 7 complexes make up polymerized filaments

  9. These results indicate that the host proteins hnRNP A1 (show HNRNPA1 Proteins) and septin 6 play important roles in the replication of HCV through RNA-protein and protein-protein interactions.

  10. crystal structures of the human SEPT2 (show SEPT2 Proteins) G domain and the heterotrimeric human SEPT2-SEPT6-SEPT7 (show SEPT7 Proteins) complex

Mouse (Murine) Septin 6 (SEPT6) interaction partners

  1. Data suggest a regulatory role for septin 6 in long-term hematopoietic stem cells (HSCs) function and lymphoid lineage differentiation.

  2. Sept6 did not alter the phenotype of myeloproliferative disease induced by MLL (show MLL Proteins)-SEPT6, thus suggesting that Sept6 does not function as a tumor suppressor.

  3. Significant level of SEPT6 expression was found in heart in a developmentally regulated fashion.

  4. Data demonstrate that the septin cytoskeleton is an integral component of the myelin sheath, and protein components such as septin 6 interact with distinct myelin constituents such as MAL.

Septin 6 (SEPT6) Protein Profile

Protein Summary

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Gene names and symbols associated with Septin 6 Proteins (SEPT6)

  • Septin 2 (Sep2)
  • septin 11 (sept11)
  • septin 8 (SEPT8)
  • septin 6 (SEPT6)
  • septin 6 (sept6)
  • septin 6 (LOC100220762)
  • septin 6 L homeolog (sept6.L)
  • septin 6 (Sept6)
  • 2810035H17Rik protein
  • C920001C06Rik protein
  • CG4173 protein
  • Dmel\\CG4173 protein
  • fc54b04 protein
  • mKIAA0128 protein
  • SEP2 protein
  • Sep6 protein
  • SEPT2 protein
  • SEPT6 protein
  • SEPT11 protein
  • septin-6 protein
  • wu:fb70g05 protein
  • wu:fc54b04 protein
  • wu:fl76c07 protein
  • zgc:66071 protein

Protein level used designations for Septin 6 Proteins (SEPT6)

CG4173-PA , CG4173-PB , Sep2-PA , Sep2-PB , myosin LC , septin , septin 2 , septin-2 , septin 11 , septin 6 , septin-6 , septin-6-like

42438 Drosophila melanogaster
447955 Xenopus (Silurana) tropicalis
462057 Pan troglodytes
694021 Macaca mulatta
100125034 Xenopus (Silurana) tropicalis
100220762 Taeniopygia guttata
100341047 Oryctolagus cuniculus
100413066 Callithrix jacchus
100433272 Pongo abelii
100563641 Anolis carolinensis
100584696 Nomascus leucogenys
322694 Danio rerio
446883 Xenopus laevis
422369 Gallus gallus
23157 Homo sapiens
612892 Canis lupus familiaris
540783 Bos taurus
56526 Mus musculus
691335 Rattus norvegicus
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