anti-Serine Racemase (SRR) Antibodies

catalyzes the conversion of L-serine to D-serine. Additionally we are shipping Serine Racemase Proteins (10) and Serine Racemase Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SRR 63826 Q9GZT4
SRR 27364 Q9QZX7
SRR 303306 Q76EQ0
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Top anti-Serine Racemase Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SRR Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HCT15 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Mouse Un-conjugated IF, WB Western blot analysis of serine racemase on a mouse cerebrum lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the anti- serine racemase antibody. 50 μg Log in to see 6 to 8 Days
$154.07
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Anti-Serine Racemase Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat kidney labeled with Anti-Serine Racemase Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-SRR mouse monoclonal antibody. (ABIN2453688, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-SRR mouse monoclonal antibody. (ABIN2453688, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-SRR mouse monoclonal antibody. (ABIN2453691, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-SRR mouse monoclonal antibody. (ABIN2453691, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-SRR mouse monoclonal antibody (ABIN2453685) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SRR (RC210359). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SRR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SRR. 100 μL Log in to see 2 to 3 Days
$423.50
Details

SRR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Serine Racemase Antibodies

  1. Mouse (Murine) Monoclonal SRR Primary Antibody for IF, WB - ABIN968726 : Mothet, Parent, Wolosker, Brady, Linden, Ferris, Rogawski, Snyder: D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Monoclonal SRR Primary Antibody for IF, WB - ABIN968727 : Wolosker, Blackshaw, Snyder: Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Serine Racemase Interaction Partners

Human Serine Racemase (SRR) interaction partners

  1. Data suggest that Ser (show SIGLEC1 Antibodies)-84 and Arg-135 are important in catalysis and substrate specificity of SRR.

  2. Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form

  3. MiR (show MLXIP Antibodies)-193a-3p and miR (show MLXIP Antibodies)-193a-5p play important roles in osteosarcoma metastasis through down-regulation of the Rab27B (show RAB27B Antibodies) and SRR genes and therefore may serve as useful biomarkers for the diagnosis of osteosarcoma

  4. Loss-of-function mutation of the gene encoding serine racemase significantly attenuates excitotoxicity in retina.

  5. Serine racemase activity and dynamics are regulated by halides, ATP and malonate.

  6. In serine racemase, similarly to the related enzyme alanine racemase, the unprotonated pyridoxal-5'-phosphate -substrate intermediate is stabilized mostly due to solvation effects contributed by water molecules and active-site residues.

  7. FBXO22 (show FBXO22 Antibodies) protein is required for optimal synthesis of NMDA receptor coagonist D-serine by interacting with serine racemase, activating it, and preventing its targeting to membranes.

  8. S84A serine racemase mutant behaved like serine dehydratase (show SDS Antibodies), whereas A65S serine dehydratase (show SDS Antibodies) mutant acquired an additional function of using D-serine as a substrate.

  9. Six SNP(rs7754840 in CDKAL1 (show CDKAL1 Antibodies), rs391300 in SRR, rs2383208 in CDKN2A (show CDKN2A Antibodies)/2B, rs4402960 in IGF2BP2 (show IGF2BP2 Antibodies), rs10830963 in MTNR1B (show MTNR1B Antibodies), rs4607517 in GCK (show GCK Antibodies))risk alleles of type 2 diabetes were associated with GDM in pregnant Chinese women.

  10. Serine racemase and D-serine are involved in both pre-symptomatic and progressive phases of amyotrophic lateral sclerosis, demonstrating a link between mutant superoxide dismutase (SOD)1 (show SOD1 Antibodies) and a glial-derived toxic mediator in transgenic mice.

Mouse (Murine) Serine Racemase (SRR) interaction partners

  1. Study to demonstrate that serine racemase inhibitor alleviates neuronal ischemic injury. Serine racemase inhibition acts on the neurovascular unit as a neuroprotectant and ameliorant of reductions in regional cerebral blood flow.

  2. These findings reveal the NMDAR (show GRIN1 Antibodies)-independent roles of SR in metabolism and cell survival.

  3. These data reveal the first evidence that Srr may regulate glucose homeostasis in peripheral tissues and provide circumstantial evidence that D-serine may be an endogenous islet NMDAR (show GRIN1 Antibodies) co-agonist in beta-cells.

  4. This study demonstrated that SR deficiency reduces retinal pigment epithelial cells response to laser-induced inflammatory stimuli, resulting in decreased production of a cascade of pro-angiogenic cytokines, including(.) NO and VEGF, and reduced macrophage recruitment, which contribute synergistically to attenuated angiogenesis.

  5. results indicate that SRR indeed acts as a d-Asp (show C3 Antibodies) biosynthetic enzyme in some organs and/or tissues, and also provide evidences that there should be some additional enzyme for d-Asp (show C3 Antibodies) synthesis in mammals.

  6. data show neuronal serine racemase could regulate the extracellular D-serine signaling responsible for N-methyl-D-aspartate type glutamate (show GRIN1 Antibodies) receptor activation in the hippocampus

  7. The retinal levels of d-serine are tightly controlled during the first week of postnatal life and vary according to deficiencies in Serine racemase.

  8. In the neocortex and hippocampus only 24-40% of interneurons expressed serine racemase.

  9. SR interacts with the synaptic proteins, postsynaptic density protein 95 (PSD-95 (show DLG4 Antibodies)) and stargazin (show CACNG2 Antibodies), forming a ternary complex.

  10. The findings of this study suggest that D-serine-dependent NMDAR (show GRIN1 Antibodies) activity is involved in mediating the cellular and behavioral effects of 5-HT2AR activation.

Serine Racemase (SRR) Antigen Profile

Protein Summary

catalyzes the conversion of L-serine to D-serine

Gene names and symbols associated with anti-Serine Racemase (SRR) Antibodies

  • serine racemase (SRR) antibody
  • serine racemase (srr) antibody
  • serine racemase (NGR_b19540) antibody
  • serine racemase (ZPR_3642) antibody
  • serine racemase (MGYG_07950) antibody
  • Serine racemase (Halhy_2637) antibody
  • Serine racemase (Runsl_3290) antibody
  • serine racemase (Srr) antibody
  • DDBDRAFT_0188432 antibody
  • DDBDRAFT_0230209 antibody
  • DDB_0188432 antibody
  • DDB_0230209 antibody
  • ILV1 antibody
  • ISO1 antibody
  • Srs antibody

Protein level used designations for anti-Serine Racemase (SRR) Antibodies

serine racemase , Serine racemase , D-serine ammonia-lyase , D-serine dehydratase , L-serine ammonia-lyase , L-serine dehydratase

GENE ID SPECIES
100355322 Oryctolagus cuniculus
703426 Macaca mulatta
747543 Pan troglodytes
771635 Gallus gallus
4196066 Roseobacter denitrificans OCh 114
7789276 Sinorhizobium fredii NGR234
8627151 Dictyostelium discoideum AX4
9079513 Zunongwangia profunda SM-A87
10025016 Arthroderma gypseum CBS 118893
10586809 Haliscomenobacter hydrossis DSM 1100
10871823 Runella slithyformis DSM 19594
100144980 Xenopus (Silurana) tropicalis
100393154 Callithrix jacchus
100587573 Nomascus leucogenys
63826 Homo sapiens
27364 Mus musculus
303306 Rattus norvegicus
525340 Bos taurus
491200 Canis lupus familiaris
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