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The protein encoded by STYX is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. Additionally we are shipping STYX Antibodies (7) and STYX Kits (2) and many more products for this protein.
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The authors show that STYX binds to the F-box domain of FBXW7 and disables its recruitment into the SCF ubiquitin ligase complex.
Results suggest that STYX is a pseudophosphatase that uses the 'competitor' and 'anchor' mode of action to exert its biologic roles. [review]
results identify STYX as an important regulator of ERK1/2 signaling critical for cell migration
We demonstrate that the phosphoserine, -threonine or -tyrosine, interaction protein, Styx, complexes with a testicular RNA-binding protein and is essential for normal spermiogenesis.
The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes.
protein tyrosine phosphatase-like protein
, serine/threonine/tyrosine-interacting protein
, phosphoserine/threonine/tyrosine interaction protein
, protein tyrosine phosphatase-like unspliced c-terminal product and spliced c-terminal end STYX