Serum Deprivation Response Proteins (SDPR)

SDPR encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. Additionally we are shipping SDPR Antibodies (37) and SDPR Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SDPR 8436 O95810
Rat SDPR SDPR 316384 Q66H98
SDPR 20324 Q63918
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Top SDPR Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details

SDPR Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Serum Deprivation Response (SDPR) Interaction Partners

Human Serum Deprivation Response (SDPR) interaction partners

  1. SDPR variants were not associated with major depressive disorder.

  2. Overall, these data suggest that Cavin-2 represents a useful marker for discriminating the degree of differentiation in LPS (show IRF6 Proteins) tumors.

  3. Data found that CVN2 expression was signi fi cantly down-regulated in oral squamous cell carcinoma (OSCC) in vitro and in vivo and that CVN2 overexpression led to decreased proliferative activities through the CVN2/caveolin-1 (show CAV1 Proteins)/ERK (show EPHB2 Proteins) path- way. Furthermore, high tumoral progression occurred in CVN2-negative patients with OSCC.

  4. Hepatocellular carcinoma patients with lower cavin-2 expression have a relatively poor prognosis.

  5. identification of a novel metastasis suppressor gene, serum deprivation response (SDPR), localized to 2q32-33, a region reported to be associated with significant loss of heterozygosity in breast cancer, is reported.

  6. Cavin-1 (show PTRF Proteins) and cavin-2 are strongly expressed within caveolae-like structures within liver sinusoidal endothelial cells of the hepatitis C-related cirrhotic liver and cavin-1 (show PTRF Proteins) would play a critical role in regulating aspects of caveolin-1 (show CAV1 Proteins).

  7. Rather than forming a single coat complex containing the three cavin (show PTRF Proteins) family members, single-molecule analysis reveals an exquisite specificity of interactions between cavin1 (show PTRF Proteins), cavin2 and cavin3 (show PRKCDBP Proteins).

  8. Three genes (LY96 (show LY96 Proteins), IL8 (show IL8 Proteins) DPR (show DACT1 Proteins)) were significantly downregulated over time. This finding was confirmed in a validation cohort of stroke patients (n=8).

  9. The cavin (show PTRF Proteins) family protein Polymerase 1 and transcript release factor, SRBC (show CD2 Proteins) and serum deprivation response protein were down regulated in breast cancer cell lines and breast tumor tissue.

  10. Study conclude that SDPR is a membrane-curvature-inducing component of caveolae, and that STB-induced membrane tubulation is facilitated by caveolae.

Mouse (Murine) Serum Deprivation Response (SDPR) interaction partners

  1. results indicate that in addition to its function in caveolae biogenesis, Cavin-2 plays a critical role in endothelial cell maintenance and function by regulating eNOS (show NOS3 Proteins) activity.

SDPR Protein Profile

Protein Summary

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.

Gene names and symbols associated with SDPR

  • caveolae associated protein 2 S homeolog (cavin2.S)
  • caveolae associated protein 2 (CAVIN2)
  • caveolae associated protein 2 (Cavin2)
  • caveolae associated 2 (Cavin2)
  • serum deprivation response (SDPR)
  • cavin-2 protein
  • CAVIN2 protein
  • MGC84112 protein
  • PS-p68 protein
  • SDR protein

Protein level used designations for SDPR

serum deprivation response , serum deprivation response (phosphatidylserine binding protein) , serum deprivation response protein , serum deprivation-response protein-like , phosphatidylserine binding protein , phosphatidylserine-binding protein , serum deprivation-response protein , cavin-2

GENE ID SPECIES
444619 Xenopus laevis
694299 Macaca mulatta
744890 Pan troglodytes
100406104 Callithrix jacchus
100432713 Pongo abelii
100598602 Nomascus leucogenys
8436 Homo sapiens
316384 Rattus norvegicus
20324 Mus musculus
100345238 Oryctolagus cuniculus
100724430 Cavia porcellus
100517010 Sus scrofa
100861147 Capra hircus
488450 Canis lupus familiaris
532333 Bos taurus
424047 Gallus gallus
101118507 Ovis aries
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