Sex Determining Region Y (SRY) ELISA Kits

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. Additionally we are shipping Sex Determining Region Y Antibodies (82) and Sex Determining Region Y Proteins (44) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SRY 6736 Q05066
SRY 25221  
SRY 21674 Q05738
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Top Sex Determining Region Y ELISA Kits at antibodies-online.com

Showing 9 out of 13 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$736.84
Details
Dog
  96 Tests 2 to 3 Days
$933.90
Details
Human
  96 Tests 2 to 3 Days
$495.00
Details
Human
  96 Tests 2 to 3 Days
$380.00
Details
Rat < 0.17 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
$731.99
Details
Human < 0.055 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$902.56
Details
Cow
  96 Tests 15 to 18 Days
$1,029.60
Details
Pig
  96 Tests 15 to 18 Days
$1,029.60
Details
Mouse
  96 Tests 15 to 18 Days
$1,029.60
Details

More ELISA Kits for Sex Determining Region Y Interaction Partners

Human Sex Determining Region Y (SRY) interaction partners

  1. SRY is a member of the SOX (SRY-like box) family of transcription factors, and is known to both positively and negatively regulate gene expression.

  2. results show that the transcriptional factor SRY specifically binds to different sites in the promoter sequence and has the ability to control CATSPER1 gene transcription.

  3. Activation of SRY and its downstream Sox9 and PDGFRalpha pathways are commonly involved in male hepatocarcinogenesis, which provides novel insights into gender disparity and sex-specific therapeutic strategies of hepatocellular carcinoma.

  4. a single-nucleotide polymorphism in the amelogenin gene using amplified product-length polymorphisms in combination with sex-determining region Y analysis, is reported.

  5. Missense Mutation 224G>T (R75M) in SRY Coding Region is associated with 46, XY Gonadal Dysgenesis.

  6. Chemical proteasome inhibition restored native-like SRY expression and transcriptional activity in association with restored occupancy of a sex-specific enhancer element in principal downstream gene Sox9, demonstrating that the variant SRY exhibits essentially native activity on a per molecule basis.

  7. SRY is involved in the maintenance of cancer stem-like characteristics through OCT4.

  8. The aim of this study was to compare two Y chromosome markers-SRY and DYS14-for their utility in the diagnosis of fetal gender

  9. These findings demonstrate that autosomal retention of SRY can be sub-microscopic and emphasize the importance of PCR and FISH in the genetic workup of the monosomic X male

  10. The SRY gene in plasma extracellular vesicles transferred to vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis

  11. Results show that SRY could be expressed in tissues of Hirschsprung patients. It binds to the promoter of RET gene by competing with SOX10 for its interaction with PAX3 and NKX2-1 repressing their transcriptional expression and RET's as well.

  12. High levels of SRY expression correlated with cancer progression and poor HCC patient survival. However, high SRY levels are not significantly correlated with HCC sex bias.

  13. Findings demonstrate that the folding, trafficking, and gene-regulatory function of testis-determining factor SRY requires an invariant aromatic "buttress" beneath its specific DNA-bending surface.

  14. Overall, these results indicated that the main mechanism of sex reversal are not associated with mutations in the coding regions of SOX9 and DAX1 or copy number variations of SOX9, which is consistent with results of previous studies.

  15. Data suggest that sex-determining region Y protein SRY upregulation after dopamine cell injury is initially a protective response in males, but diminishes with gradual loss in dopamine cells.

  16. A proximal promoter construct for the MAS gene was repressed by the SOX [SRY (sex-determining region on the Y chromosome) box] proteins SRY, SOX2, SOX3 and SOX14, of which SRY is known to interact with the KRAB domain.

  17. Nucleocytoplasmic shuttling of SRY is necessary for robust initiation of testicular development.

  18. SRY may act as a transcription repressor for pluripotency-associated genes and as a transcription activator for differentiation-related genes in embryonic cells.

  19. SRY plays a role as a positive regulator of catecholamine synthesis and metabolism in the human male

  20. A novel SRY mutation leads to asymmetric SOX9 activation and is responsible for mixed 46,XY gonadal dysgenesis.

Cow (Bovine) Sex Determining Region Y (SRY) interaction partners

  1. analysis of mtDNA control region sequences and SRY gene sequences indicated more contribution to the Yunnan cattle from B. indicus than from B. taurus

  2. Mapped to the bovine Y chromosome (BTAY) by fluorescence in situ hybridization (FISH) and/or radiation hybrid (RH) mapping.

  3. New insights into SRY regulation through identification of 5' conserved sequence are reported.

Pig (Porcine) Sex Determining Region Y (SRY) interaction partners

  1. The 4.6 Kb of pig SRY 5' flanking sequences supported reporter transgene expression within the male genital ridge but not within the neural crest.

  2. New insights into SRY regulation through identification of 5' conserved sequence are reported.

Horse (Equine) Sex Determining Region Y (SRY) interaction partners

  1. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse.

Rabbit Sex Determining Region Y (SRY) interaction partners

  1. CRISPR/Cas9-mediated mosaic mutation of SRY gene induces hermaphroditism in rabbits.

  2. our study demonstrates that Sp1 is a major regulator in SRY gene transcription, and mutations of the Sp1 binding sites (Sp1-B and Sp1-C) in the 5' flanking region of SRY induce sex reversal in rabbits

  3. Gene conversion is a general feature of the evolution of the mammalian Y chromosome.

Mouse (Murine) Sex Determining Region Y (SRY) interaction partners

  1. Activation of SRY and its downstream Sox9 and PDGFRalpha pathways are commonly involved in male hepatocarcinogenesis, which provides novel insights into gender disparity and sex-specific therapeutic strategies of hepatocellular carcinoma.

  2. MAP2K6 functions in mouse testis determination, via positive effects on Sry, and a minor role for MAP2K3.

  3. our findings support that males lacking the testis determinant Sry can be fertile and reinforce the notion that Sry does not play a role in mature gonads.

  4. Variations in Usp9y and the number of CAG repeats in Sry are significantly associated with testes weight.

  5. Sry can be replaced by transgenic activation of its downstream target Sox9. This finding supports the existence of functional redundancy between the Y chromosome genes and their homologs encoded on other chromosomes.

  6. SRY binds to various ovarian differentiation genes and represses their activation through WNT/beta-catenin signaling.

  7. The SRY gene in plasma extracellular vesicles transferred to vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis

  8. Studies indicate that in most of mammals, a single genetic trigger, the Y-linked gene Sry (sex determination region on Y chromosome), regulates testicular differentiation.

  9. disprove the hypothesis that the conserved HMG box domain is the only functional domain of Sry, and highlight an evolutionary paradox whereby mouse Sry has evolved a novel bifunctional module to activate Sox9 directly

  10. this study demonstrates that live mouse progeny can also be generated by using germ cells from males with the Y chromosome contribution limited to only two genes, the testis determinant factor Sry and the spermatogonial proliferation factor Eif2s3y.

  11. Microsatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological novelty.

  12. 70-kDa heat shock cognate protein hsc70 mediates calmodulin-dependent nuclear import of the sex-determining factor SRY.

  13. Data from knockout mice suggest that spermiogenesis can be initiated whether or not second meiotic division has taken place, and even when the only Y genes present are Sry and Eif2s3y.

  14. mice lacking Gadd45gamma also exhibit XY gonadal sex reversal caused by disruption to Sry expression

  15. suggest that a signaling cascade, involving GADD45G --> p38 MAPK --> GATA4 --> SRY, regulates male sex determination

  16. Data propose that SRY/Sry may function as a male-specific maturation factor in the peri-implantation mammalian embryo.

  17. Data suggest a mechanism by which SRY induces Sox9 and Er71 transcription early in testis differentiation.

  18. Factor SRY is the key trigger of mammalian sex determination by means of initiation the autosomal gene SOX9 expression. (Review)

  19. This study implicates Cbx2 in testis differentiation through regulating Sry gene expression.

  20. The results of this study suggest that gender indeed influences several PD-related gene expressions in VM neurons, and SRY and estrogen are involved in the different responses to oxidative stress in culture.

Sex Determining Region Y (SRY) Antigen Profile

Antigen Summary

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome)\; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Gene names and symbols associated with SRY

  • sex determining region Y (SRY) antibody
  • sex determining region Y (Sry) antibody
  • sex determining region of Chr Y (Sry) antibody
  • SRXX1 antibody
  • SRXY1 antibody
  • SRY antibody
  • Sry1 antibody
  • Sry3BI antibody
  • SRYGENE antibody
  • Tdf antibody
  • Tdy antibody

Protein level used designations for SRY

essential protein for sex determination in human males , sex-determining region Y protein , sex-determining region on Y , testis-determining factor on Y , HMG box transcription factor Sry1 , HMG box transcription factor Sry3BI , Testis determining locus , sex determining region of Chr Y , sex determining region on Y , testis-determining factor , sex determining factor Y , sex-determining region of the Y-chromosome , sex determining region Y protein , sex-determining protein , sex determining region Y , testis determining-Y , Sex-determining region Y protein , Testis-determining factor , sex determining region Y variant A , sex determining region Y variant B , testis determining factor , sex determining factor SRY , testis determining factor SRY

GENE ID SPECIES
6736 Homo sapiens
25221 Rattus norvegicus
280931 Bos taurus
407740 Sus scrofa
449510 Pan troglodytes
493758 Felis catus
574155 Macaca mulatta
100033824 Equus caballus
100328958 Oryctolagus cuniculus
21674 Mus musculus
100529253 Ovis aries
108634533 Capra hircus
109555752 Bos indicus
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