Sialic Acid Binding Ig-Like Lectin 12 (Gene/pseudogene) Proteins (SIGLEC12)

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. Additionally we are shipping SIGLEC12 Antibodies (57) and SIGLEC12 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SIGLEC12 89858 Q96PQ1
SIGLEC12 83382 Q91Y57
SIGLEC12 450120 Q95LH0
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Top SIGLEC12 Proteins at antibodies-online.com

Showing 9 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$778.00
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$225.40
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
Details
Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 15 to 18 Days
$560.00
Details
Yeast Chimpanzee His tag   1 mg Log in to see 60 to 71 Days
$3,303.67
Details
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$554.33
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$696.46
Details

SIGLEC12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,
,
Chimpanzee

More Proteins for Sialic Acid Binding Ig-Like Lectin 12 (Gene/pseudogene) (SIGLEC12) Interaction Partners

Human Sialic Acid Binding Ig-Like Lectin 12 (Gene/pseudogene) (SIGLEC12) interaction partners

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 12 (Gene/pseudogene) (SIGLEC12) interaction partners

SIGLEC12 Protein Profile

Protein Summary

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.

Gene names and symbols associated with SIGLEC12

  • sialic acid-binding Ig-like lectin 13 (LOC484344)
  • sialic acid binding Ig like lectin 12 (SIGLEC12)
  • sialic acid binding Ig like lectin 12 (gene/pseudogene) (SIGLEC12)
  • sialic acid-binding Ig-like lectin 13 (LOC618463)
  • sialic acid binding Ig-like lectin E (Siglece)
  • Cd170 protein
  • mSiglec-E protein
  • S2V protein
  • Siglec-XII protein
  • Siglec5 protein
  • Siglec9 protein
  • Siglec12 protein
  • Siglecl1 protein
  • SLG protein

Protein level used designations for SIGLEC12

SIGLEC-like 1 , sialic acid binding immunoglobulin-like lectin-like protein 1 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding lectin Siglec-L1 , siglec-12 , siglec-L1 , sialic acid binding Ig-like lectin 12 , MIS , myeloid inhibitory siglec , sialic acid binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin E , sialic acid-binding immunoglobulin-like lectin E , siglec-5 , siglec-E

GENE ID SPECIES
484344 Canis lupus familiaris
450120 Pan troglodytes
89858 Homo sapiens
618463 Bos taurus
83382 Mus musculus
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