SIGLEC12 Proteins

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily.

Data Quality
  • 12
Type
  • 15
    Protein
Antigen
  • 15
Reactivity
  • 10
  • 4
  • 1
Application
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  • 10
  • 6
  • 4
Host
  • 6
  • 4
  • 3
  • 1
  • 1
Binding Specificity
  • 1
  • 1
  • 1
  • 1
  • 1
Conjugate
  • 3
  • 6
  • 3
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  • 1
Protein Type
  • 15
Format
  • 7
  • 4
Suggested next Filters
15 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3127482
$5,122.60
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3127481
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3076904
$7,294.44
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3076905
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN2752933
$230.67
2 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1319987
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1319989
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3011644
$759.77
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3011645
$759.77
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN2122081
$777.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN2122082
$777.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2732049
$932.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityMouse (Murine)
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN1099458
$560.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityMouse (Murine)
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3011643
$590.93
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityChimpanzee
Application ELISA
Order details Cat. No. ABIN1641406
$3,303.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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SIGLEC12 Protein Profile

Protein Summary

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.

Gene names and symbols associated with SIGLEC12

  • sialic acid binding Ig like lectin 12 (gene/pseudogene) (SIGLEC12) antibody
  • sialic acid binding Ig like lectin 12 (SIGLEC12) antibody
  • sialic acid binding Ig-like lectin 12 (SIGLEC12) antibody
  • S2V antibody
  • Siglec-XII antibody
  • SIGLECL1 antibody
  • SLG antibody

Protein level used designations for SIGLEC12

SIGLEC-like 1 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin-like 1 , sialic acid binding immunoglobulin-like lectin-like protein 1 , sialic acid-binding lectin Siglec-L1 , siglec-12 , siglec-L1

GENE ID SPECIES
89858 Homo sapiens
450120 Pan troglodytes
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