anti-SPPL2B Antibodies

SPPL2B encodes a member of the GXGD family of aspartic proteases.

Data Quality
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Type
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    Primary antibodies
Antigen
  • 7
Reactivity
  • 7
  • 3
  • 3
  • 2
  • 2
Application
  • 7
  • 4
  • 2
  • 1
  • 1
Host
  • 7
Clonality
  • 7
Binding Specificity
  • 3
  • 1
  • 1
Isotype
  • 2
Format
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  • 3
7 Products
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN634985
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN2782090
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityCow (Bovine), Human
Application IHC, IHC (p), WB
Order details Cat. No. ABIN6738138
$581.17
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityCow (Bovine), Horse (Equine), Human, Pig (Porcine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN2782089
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application IHC, ELISA, WB
Order details Cat. No. ABIN2464000
$550.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN1386177
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 7 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN6752476
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
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SPPL2B Antigen Profile

Protein Summary

This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPPL2B

  • signal peptide peptidase-like 2 (sppl2) antibody
  • signal peptide peptidase like 2B (sppl2b) antibody
  • signal peptide peptidase like 2B S homeolog (sppl2b.S) antibody
  • signal peptide peptidase like 2B (SPPL2B) antibody
  • signal peptide peptidase like 2B (Sppl2b) antibody
  • signal peptide peptidase-like 2B (Sppl2b) antibody
  • 3110056O03Rik antibody
  • AW550292 antibody
  • IMP-4 antibody
  • IMP4 antibody
  • MGC147524 antibody
  • PSH4 antibody
  • PSL1 antibody
  • RGD1308556 antibody
  • SPPL2B antibody
  • wu:fc16e01 antibody
  • wu:fc85d12 antibody
  • zgc:136525 antibody

Protein level used designations for SPPL2B

signal peptide peptidase-like 2B , signal peptide peptidase-like protein 2 , SPP-like 2B , protein SPP-like 2B , protein SPPL2b , intramembrane protease 4 , presenilin homologous protein 4 , presenilin-like protein 1

GENE ID SPECIES
325540 Danio rerio
780336 Xenopus (Silurana) tropicalis
379574 Xenopus laevis
420056 Gallus gallus
56928 Homo sapiens
73218 Mus musculus
504285 Bos taurus
362828 Rattus norvegicus
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