Slingshot Protein Phosphatase 2 (SSH2) ELISA Kits

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SSH2 SSH2 85464 Q76I76
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.113 ng/mL 0.312 ng/mL - 20 ng/mL 96 Tests Log in to see 15 to 17 Days

More ELISA Kits for Slingshot Protein Phosphatase 2 Interaction Partners

Human Slingshot Protein Phosphatase 2 (SSH2) interaction partners

  1. Novel signaling pathway consisting of chemoattractant GPCR/Galphai protein, PLC, PKCbeta and PKDs that regulates SSH2/cofilin activity, F-actin polymerization and directional assembly of actin cytoskeleton in neutrophil chemotaxis was identified.

  2. data indicate that: (a) apoptotic cell death in FLCN (show FLCN ELISA Kits)-null cells can be triggered by SSH2 knockdown through cell cycle arrest; (b) SSH2 represents a potential therapeutic target for the development of agents for the treatment of BHD (show FLCN ELISA Kits) syndrome related tumors

  3. Expression of phosphatase-dead versions of SSH proteins, SSH1 (show SSH1 ELISA Kits), SSH2 & SSH3 (show SSH3 ELISA Kits) results in phosphorylation/inactivation of cofilin (show CFL1 ELISA Kits), changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes.

Slingshot Protein Phosphatase 2 (SSH2) Antigen Profile

Antigen Summary

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1\; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002

Gene names and symbols associated with SSH2

  • slingshot protein phosphatase 2 (SSH2) antibody
  • SSH-2 antibody
  • SSH-2L antibody

Protein level used designations for SSH2

SSH-like protein 2 , protein phosphatase Slingshot homolog 2

85464 Homo sapiens
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