Small EDRK-Rich Factor 1A (Telomeric) Proteins

SERF1A is part of a 500 kb inverted duplication on chromosome 5q13.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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5 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3132255
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1319575
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1319577
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2731710
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1626465
$2,057.00
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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Small EDRK-Rich Factor 1A (Telomeric) (SERF1A) Protein Profile

Protein Summary

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known\; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene.

Gene names and symbols associated with SERF1A

  • small EDRK-rich factor 1A (SERF1A) antibody
  • small EDRK-rich factor 1 (Serf1) antibody
  • small EDRK-rich factor 1A (telomeric) (SERF1A) antibody
  • 4F5 antibody
  • FAM2A antibody
  • H4F5 antibody
  • m4F5 antibody
  • Msmac1 antibody
  • SERF1 antibody
  • SERF1B antibody
  • SMAM1 antibody

Protein level used designations for SERF1A

SMA modifier 1 , protein 4F5 , small EDRK-rich factor 1 , spinal muscular atrophy-related gene H4F5 , modifier of spinal muscular atrophy candidate 1 , small EDRK-rich factor 1A, telomeric , small EDRK-rich factor 1B (centromeric)

GENE ID SPECIES
8293 Homo sapiens
20365 Mus musculus
526395 Bos taurus
100358992 Oryctolagus cuniculus
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