Small EDRK-Rich Factor 1A (Telomeric) Proteins (SERF1A)

SERF1A is part of a 500 kb inverted duplication on chromosome 5q13. Additionally we are shipping Small EDRK-Rich Factor 1A (Telomeric) Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERF1A 8293 O75920
SERF1A 20365 O88892
SERF1A 526395 Q32P76
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Top Small EDRK-Rich Factor 1A (Telomeric) Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days

SERF1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

Cow (Bovine)

More Proteins for Small EDRK-Rich Factor 1A (Telomeric) (SERF1A) Interaction Partners

Human Small EDRK-Rich Factor 1A (Telomeric) (SERF1A) interaction partners

  1. Inverse correlation was observed between SMN2, SERF1A and NAIP copy number polymorphism and spinal muscular atrophy type.

  2. the autonomous amyloid-modifying activity of SERF1a observed in living organisms relies on a direct and dedicated manipulation of the early stages in the amyloid aggregation pathway.

  3. There is a close relationship between SMN2, NAIP and H4F5 gene copy number and spinal muscular atrophy disease severity

  4. The human orthologs of MOAG-4, SERF2 and SERF1A, are ubiquitously expressed, consistent with a role in a general cellular pathway.

Small EDRK-Rich Factor 1A (Telomeric) (SERF1A) Protein Profile

Protein Summary

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known\; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene.

Gene names and symbols associated with SERF1A

  • small EDRK-rich factor 1A (SERF1A)
  • small EDRK-rich factor 1 (Serf1)
  • small EDRK-rich factor 1A (telomeric) (SERF1A)
  • 4F5 protein
  • FAM2A protein
  • H4F5 protein
  • m4F5 protein
  • Msmac1 protein
  • SERF1 protein
  • SERF1B protein
  • SMAM1 protein

Protein level used designations for SERF1A

SMA modifier 1 , protein 4F5 , small EDRK-rich factor 1 , spinal muscular atrophy-related gene H4F5 , modifier of spinal muscular atrophy candidate 1 , small EDRK-rich factor 1A, telomeric , small EDRK-rich factor 1B (centromeric)

8293 Homo sapiens
20365 Mus musculus
526395 Bos taurus
100358992 Oryctolagus cuniculus
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