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Likely involved in U12-type 5' splice site recognition.. Additionally we are shipping SNRNP48 Proteins (3) and and many more products for this protein.
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Using site-specific cross-linking, we detected an interaction between the U11-48K protein and U12-type 5' splice sites (5'ss).
RNA interference-induced knockdown of 48K led to reduced cell growth and the inhibition of U12-type splicing, as well as the activation of cryptic, U2-type splice sites, suggesting that 48K plays a critical role in U12-type intron recognition.
A model in which the U11-48K Zn finger stabilizes U11-5' splice site base pairing and thus plays an important role during the minor spliceosome assembly.
Likely involved in U12-type 5' splice site recognition.
U11/U12 small nuclear ribonucleoprotein 48 kDa protein
, U11/U12 snRNP 48 kDa protein
, U11/U12 snRNP 48K