anti-Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) Antibodies

SMCR7 encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. Additionally we are shipping SMCR7 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SMCR7 237781 Q5NCS9
SMCR7 125170 Q96C03
SMCR7 497916  
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Top anti-SMCR7 Antibodies at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Guinea Pig Rabbit Un-conjugated WB Host: Rabbit Target Name: SMCR7 Sample Type: HT1080 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: SMCR7 Sample Type: MCF7 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western Blot: SMCR7 Antibody [NBP2-20421] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000. Western Blot: SMCR7 Antibody [NBP2-20421] - Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE gel, diluted at 1:500. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: SMCR7 Antibody [NBP1-81165] - Staining of human heart muscle shows moderate cytoplasmic positivity in myocytes. Western Blot: SMCR7 Antibody [NBP1-81165] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining of human heart muscle with SMCR7 polyclonal antibody  shows moderate cytoplasmic positivity in myocytes. Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with SMCR7 polyclonal antibody . 100 μL Log in to see 11 to 12 Days
$460.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SMCR7 is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (75.7 KDa) . 100 μg Log in to see 11 to 12 Days
$354.20
Details

More Antibodies against SMCR7 Interaction Partners

Human Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) interaction partners

  1. Knockdown of MIEF2 reduces DOX-induced mitochondrial fission and apoptosis in cardiomyocytes and in vivo. Also, knockdown of MIEF2 protects heart from DOX-induced cardiotoxicity. Our study identifies a novel pathway composed of Foxo3a (show FOXO3 Antibodies) and MIEF2 that mediates DOX cardiotoxicity.

  2. MiD49 and MiD51 (show SMCR7L Antibodies) recruit inactive forms of Drp1 (show CRMP1 Antibodies) in mitochondrial fission. [review]

  3. These findings and data showing MARCH5 (show MARCH5 Antibodies)-dependent degradation of MiD49 upon stress support the possibility that MARCH5 (show MARCH5 Antibodies) regulation of MiD49 is a novel mechanism controlling mitochondrial fission and, consequently, the cellular response to stress.

  4. The results indicate that Drp1 (show CRMP1 Antibodies)-dependent mitochondrial fission through MiD49/MiD51 (show SMCR7L Antibodies) regulates cristae remodeling during intrinsic apoptosis.

  5. MIEF1 (show SMCR7L Antibodies) and MIEF2 are differentially expressed in human tissues during development

  6. MiD49 and MiD51 (show SMCR7L Antibodies) can act independently of Mff (show MFF Antibodies) and Fis1 (show FIS1 Antibodies) in Drp1 (show CRMP1 Antibodies) recruitment and suggest that they provide specificity to the division of mitochondria.

  7. we find that either MiD49 or MiD51 (show SMCR7L Antibodies) can mediate Drp1 (show CRMP1 Antibodies) recruitment and mitochondrial fission in the absence of Fis1 (show FIS1 Antibodies) and Mff (show MFF Antibodies).

  8. Mitochondrial outer membrane protein (show TOMM40 Antibodies) that recruits fission mediator Drp1 (show CRMP1 Antibodies) to the mitochondrial surface.

Mouse (Murine) Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) interaction partners

  1. MiD51 (show SMCR7L Antibodies) can suppress Mff (show MFF Antibodies)-dependent enhancement of Drp1 (show CRMP1 Antibodies) GTPase (show RACGAP1 Antibodies) activity.

  2. This paper combines confocal live-cell imaging with correlative cryogenic fluorescence microscopy and soft x-ray tomography to link MiD49 and MiD51 (show SMCR7L Antibodies) to the involvement of the endoplasmic reticulum in mitochondrial fission.

  3. Determined the crystal structure and fperformed unctional analysis of mouse MiD49.

  4. MiD49 and MiD51 (show SMCR7L Antibodies) can act independently of Mff (show MFF Antibodies) and Fis1 (show FIS1 Antibodies) in Drp1 (show CRMP1 Antibodies) recruitment and suggest that they provide specificity to the division of mitochondria.

SMCR7 Antigen Profile

Protein Summary

This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with SMCR7

  • mitochondrial elongation factor 2 (Mief2) antibody
  • mitochondrial elongation factor 2 (MIEF2) antibody
  • mitochondrial elongation factor 2 S homeolog (mief2.S) antibody
  • mitochondrial elongation factor 2 (mief2) antibody
  • AI482195 antibody
  • Gm11 antibody
  • im:7149098 antibody
  • mid49 antibody
  • RGD1560728 antibody
  • smcr7 antibody
  • smcr7b antibody
  • zgc:152920 antibody

Protein level used designations for SMCR7

mitochondrial dynamic protein MID49 , mitochondrial dynamic protein of 49 kDa homolog , smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog , Smith-Magenis syndrome chromosomal region candidate gene 7 protein , mitochondrial dynamic protein of 49 kDa , Smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog , Smith-Magenis syndrome chromosome region, candidate 7 , mitochondrial dynamics protein MID49 , Smith-Magenis syndrome chromosome region, candidate 7 homolog , Smith-Magenis syndrome chromosome region, candidate 7b

GENE ID SPECIES
237781 Mus musculus
125170 Homo sapiens
443935 Xenopus laevis
100728873 Cavia porcellus
497916 Rattus norvegicus
100050635 Equus caballus
609352 Canis lupus familiaris
515229 Bos taurus
767710 Danio rerio
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