Sodium Dependent Vitamin C Transporter 1 (SVCT1) ELISA Kits

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. Additionally we are shipping Sodium Dependent Vitamin C Transporter 1 Antibodies (29) and Sodium Dependent Vitamin C Transporter 1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SVCT1 9963 Q9UHI7
SVCT1 20522 Q9Z2J0
SVCT1 50621 Q9WTW7
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Top Sodium Dependent Vitamin C Transporter 1 ELISA Kits at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Mouse < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Rat < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details

More ELISA Kits for Sodium Dependent Vitamin C Transporter 1 Interaction Partners

Human Sodium Dependent Vitamin C Transporter 1 (SVCT1) interaction partners

  1. Our findings show, for the first time, that transporters of the water-soluble vitamin ascorbic acid (i.e., the vitamin C transporters SVCT-1 and SVCT-2) are differentially expressed along the length of the intestinal tract and that the pattern of expression is mediated, at least in part, by transcriptional and epigenetic mechanism(s) affecting both Slc23a1 and Slc23a2 genes.

  2. consensus site for HNF1 (show HNF1A ELISA Kits) that is crucial for the regulation of the human SVCT1 promoter is present in the SVCT1 rat promoter but has no effect on its transcriptional activity

  3. SNP rs6596473 of SLC23A1 is suggested to be associated with AgP. results add to previous reports vitamin C plays a role in pathogenesis of periodontitis.

  4. Data from observational/genetic association studies in Europe suggest an SNP in SLC23A1 (rs33972313) is associated with up-regulation of circulating L-ascorbic acid but not with any cardiometabolic/cardiovascular outcome investigated. [META-ANALYSIS]

  5. The SVCT1 was induced and localized to the apical membrane of tubular epithelial cells.

  6. polymorphisms in SLC23A1/2 genes influenced ascorbate concentration in aqueous humor and lens nucleus.

  7. A genetic variant in the SLC23A1 ascorbate transporter locus was identified and is associated with an increased risk of Crohn disease in a white Canadian inflammatory bowel diseases cohort.

  8. Data show that the mRNA level of svct2 was approximately 600- to 900-fold higher than that of svct1 indicating SVCT2 is a main isoform in fibroblast OUMS-36 cells, and no significant difference in svct2 mRNA and protein between young and old cells.

  9. Data suggest that N-terminal and C-terminal sorting signals interact, directly or indirectly, within each gene family (here, SVCT1 and SVCT2) in basolateral targeting of transmembrane proteins to basolateral cell membrane.

  10. SVCT1 directly interacts with GRHPR (show GRHPR ELISA Kits).

Mouse (Murine) Sodium Dependent Vitamin C Transporter 1 (SVCT1) interaction partners

  1. Aging modulates vitamin C transporter expression. Renal over-expression of SVCT1 enhances vitamin C reabsorption in aged animals that may synthesize less vitamin C.

  2. The SVCT1 was induced and localized to the apical membrane of tubular epithelial cells.

  3. a key role for Slc23a1 in renal ascorbate absorption and perinatal survival and reveal regulation of vitamin C biosynthesis in mice.

  4. By using primary cultured hepatocytes from SMP30/GNL (show RGN ELISA Kits) KO mice, we found that SVCT1 and SVCT2 mRNA expression levels and AA uptake ability were significantly enhanced in the hepatocytes of ascorbic acid-depleted SMP30/GNL (show RGN ELISA Kits) KO mice.

  5. SVCT2 is major determinant of ascorbate accumulation in tissues lacking SVCT1. SVCT isoforms appear to function independently of one another. SVCT1 expression and ascorbate concentrations in SVCT1-predominant organs were not affected by SVCT2 deficiency.

  6. SVCT1 is responsible for epidermal ascorbic acid supply, whereas SVCT2 mainly facilitates ascorbic acid transport in the dermal compartment

  7. PPARalpha up-regulates the expression of Slc23a1 in small intestine.

Sodium Dependent Vitamin C Transporter 1 (SVCT1) Antigen Profile

Antigen Summary

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SVCT1

  • solute carrier family 23 member 1 (SLC23A1) antibody
  • solute carrier family 23 (nucleobase transporters), member 1 (Slc23a1) antibody
  • solute carrier family 23 member 1 (Slc23a1) antibody
  • D18Ucla2 antibody
  • Slc23a2 antibody
  • SVCT1 antibody
  • YSPL3 antibody

Protein level used designations for SVCT1

Na(+)/L-ascorbic acid transporter 1 , hSVCT1 , sodium-dependent vitamin C transporter 1 , sodium-dependent vitamin C transporter-1 , solute carrier family 23 (nucleobase transporters), member 1 , solute carrier family 23 (nucleobase transporters), member 2 , solute carrier family 23 member 1 , yolk sac permease-like molecule 3 , sodium-coupled ascorbic acid transporter 1 , sodium-coupled ascorbic acid transporter 1

GENE ID SPECIES
9963 Homo sapiens
20522 Mus musculus
50621 Rattus norvegicus
396578 Sus scrofa
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