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anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 (SLC12A4) Antibodies

SLC12A4 encodes a member of the SLC12A transporter family. Additionally we are shipping Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC12A4 6560 Q9UP95
SLC12A4 20498 Q9JIS8
SLC12A4 29501 Q63632
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Top anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SLC12A4 Antibody Titration: 0.2-1 ug/ml Positive Control: PANC1 cell lysate There is BioGPS gene expression data showing that SLC12A4 is expressed in PANC1 WB Suggested Anti-SLC12A4 Antibody Titration: 0.2-1 µg/mL Positive Control: PANC1 cell lysate There is BioGPS gene expression data showing that SLC12A4 is expressed in PANC1 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN238576 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with SLC12A4 antibody ABIN337105 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-SLC12A4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$495.00
Details
Dog Goat Un-conjugated WB   0.1 mg Log in to see 4 to 8 Days
$462.00
Details
Bat Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Brain Tissue using SLC12A4 Rabbit Polyclonal Antibody diluted at 1:200. Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain Tissue using SLC12A4 Rabbit Polyclonal Antibody diluted at 1:200. 100 μL Log in to see Available
$363.46
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 12 to 14 Days
$686.14
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$515.63
Details
Human Goat Un-conjugated ELISA, WB 200 μL Log in to see 7 to 11 Days
$397.98
Details

Top referenced anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 Antibodies

  1. Human Polyclonal SLC12A4 Primary Antibody for ELISA, IHC (p) - ABIN451604 : Simard, Bergeron, Frenette-Cotton, Carpentier, Pelchat, Caron, Isenring: Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters. in The Journal of biological chemistry 2007 (PubMed)

  2. Human Polyclonal SLC12A4 Primary Antibody for ELISA, IHC - ABIN238576 : Wei, Akerman, Newey, Pan, Clinch, Jacob, Shen, Wilkins, Ellory: The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism. in The Journal of physiology 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 Interaction Partners

Human Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 (SLC12A4) interaction partners

  1. data indicate that Zn(2+) acting via ZnR/GPR39 has a direct role in controlling Cl(-) absorption via upregulation of basolateral KCC1 in the colon. Moreover, colonocytic ZnR/GPR39 and KCC1 reduce water loss during diarrhea and may therefore serve as effective drug targets.

  2. The Wnk3 protein isoforms have a similar effect on SLC12 cotransporters. NKCC1/2 and NCC were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions.

  3. Insulin-like growth factors I can induce the upregulation of KCC1 gene, and KCC1 gene participates in the invasion ability of HEC-1B cells through the ERK signaling pathway.

  4. KCC3 is the dominant isoform in erythrocytes, with variable expression of KCC1 and KCC4 that could result in modulation of KCC activity

  5. human osteoblasts express functional K-Cl cotransporters in their cell membrane that seem to be able to induce the indirect activation of volume-sensitive Cl- channels by KCl through an increase in intracellular ions, water influx and cell swelling.

  6. loss-of-function KCC mutant cervical cancer cells exhibit inhibited cell growth accompanied by decreased activity of cell cycle gene products

  7. the KCC1 gene promoter lacks a TATA box and is composed of an initiator element (InR) and a downstream promoter element (DPE)

  8. Hb polymerisation and sickling could be dissociated from the abnormal response of KCC to deoxygenation observed in HbS-containing red cells.

  9. KCC activation by IGF-1 plays an important role in IGF-1 signaling to promote growth and spread of gynecological cancers.

  10. IGF-II (insulin-like growth factors-2) can enhance KCC1 (KC1 co-transport-1) gene expression in cervical cancer cells through signal transduction pathways

Mouse (Murine) Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 (SLC12A4) interaction partners

  1. data indicate that Zn(2+) acting via ZnR/GPR39 has a direct role in controlling Cl(-) absorption via upregulation of basolateral KCC1 in the colon. Moreover, colonocytic ZnR/GPR39 and KCC1 reduce water loss during diarrhea and may therefore serve as effective drug targets.

  2. We show that a single mutant allele of Kcc1 induces widespread sickling and tissue damage, leading to premature death in a humanized mouse model of sickle cell disease

  3. KCC3 is the dominant isoform in erythrocytes, with variable expression of KCC1 and KCC4 that could result in modulation of KCC activity

  4. Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1) with the cotransporters KCC3, NKCC1, and NKCC2 but not KCC1 and KCC4

  5. Treatment of cells expressing mouse K-Cl cotransporter Kcc1 with several chemical cross-linkers shifted Kcc1 polypeptide to higher MW forms. The N-terminal & C-terminal cytoplasmic tails of Kcc1 were not essential for Kcc1 crosslinking.

Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 (SLC12A4) Antigen Profile

Protein Summary

This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with SLC12A4

  • solute carrier family 12 member 4 (SLC12A4) antibody
  • solute carrier family 12 (potassium/chloride transporter), member 4 L homeolog (slc12a4.L) antibody
  • solute carrier family 12, member 4 (Slc12a4) antibody
  • solute carrier family 12 member 4 (Slc12a4) antibody
  • AW546649 antibody
  • Kcc1 antibody
  • RBCKCC1 antibody
  • SLC12A4 antibody

Protein level used designations for SLC12A4

electroneutral potassium-chloride cotransporter 1 , erythroid K-Cl cotransporter 1 , hKCC1 , potassium/chloride cotransporter 1 , solute carrier family 12 (potassium/chloride transporters), member 4 , solute carrier family 12 member 4 , K-Cl Co-transporter-1 , K-Cl cotransporter KCC1 , mKCC1 , furosemide-sensitive K-Cl cotransporter , rKCC1 , solute carrier family 12, member 4 , K-Cl cotransporter 1 , K-Cl cotransporter 4

GENE ID SPECIES
6560 Homo sapiens
398663 Xenopus laevis
454181 Pan troglodytes
533876 Bos taurus
701196 Macaca mulatta
100009441 Oryctolagus cuniculus
20498 Mus musculus
29501 Rattus norvegicus
479679 Canis lupus familiaris
100729548 Cavia porcellus
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