Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 Proteins

SLC12A3 encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis.

Data Quality
  • 10
Type
  • 11
    Protein
Target
  • 11
Reactivity
  • 8
  • 3
Application
  • 10
  • 10
  • 10
  • 6
  • 4
Host
  • 5
  • 5
  • 1
Binding Specificity
  • 2
  • 1
  • 1
  • 1
  • 1
Conjugate
  • 1
  • 7
  • 2
  • 1
Protein Type
  • 11
Format
  • 8
  • 2
Suggested next Filters
11 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3120615
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3087801
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3087802
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3120614
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3134551
$10,931.48
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 70 to 75 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3095205
$15,592.82
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 70 to 75 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN1099325
$636.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN2121750
$636.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3010860
$647.21
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2732145
$932.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN1525530
$420.00
100 μg
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
  • <
  • 1
  • >

Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3) Protein Profile

Protein Summary

This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC12A3

  • solute carrier family 12 member 3 (SLC12A3) antibody
  • solute carrier family 12 (sodium/chloride transporter), member 3 (slc12a3.2) antibody
  • solute carrier family 12 member 3 (Slc12a3) antibody
  • solute carrier family 12, member 3 (Slc12a3) antibody
  • AI035291 antibody
  • DKFZp469N2315 antibody
  • NCC antibody
  • NCCT antibody
  • slc12a3 antibody
  • TSC antibody

Protein level used designations for SLC12A3

solute carrier family 12 (sodium/chloride transporters), member 3 , thiazide-sensitive sodium chloride cotransporter , solute carrier family 12 (sodium/chloride transporters), member 3, gene 2 , solute carrier family 12 member 3-like , Na-Cl cotransporter , Na-Cl symporter , NaCl electroneutral thiazide-sensitive cotransporter , solute carrier family 12 member 3 , thiazide-sensitive Na-Cl cotransporter , thiazide-sensitive sodium-chloride cotransporter , solute carrier family 12, member 3 , sodium chloride cotransporter

GENE ID SPECIES
415692 Gallus gallus
454108 Pan troglodytes
703090 Macaca mulatta
100009348 Oryctolagus cuniculus
100038063 Xenopus (Silurana) tropicalis
100051953 Equus caballus
100172399 Pongo abelii
100409101 Callithrix jacchus
100468795 Ailuropoda melanoleuca
100015656 Monodelphis domestica
6559 Homo sapiens
54300 Rattus norvegicus
478118 Canis lupus familiaris
404171 Bos taurus
20497 Mus musculus