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SKP2 Proteins

(S-Phase Kinase-Associated Protein 2 (SKP2))
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class\; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2011].
SKP2 Protein (AA 176-285) (GST tag) SKP2 Protein (AA 176-285) (GST tag) SKP2 Protein (AA 176-285) (GST tag) (ABIN1320093)

SKP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SKP2 Protein (AA 1-424) (GST tag) SKP2 Protein (AA 1-424) (GST tag) SKP2 Protein (AA 1-424) (GST tag) (ABIN1320091)

SKP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SKP2 Protein (AA 1-424) (His tag) SKP2 Protein (AA 1-424) (His tag) SKP2 Protein (AA 1-424) (His tag) (ABIN3095574)

Crystallography grade SKP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

SKP2 Proteins by Grade

Find SKP2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SKP2 Proteins by Origin

Find SKP2 Proteins for a variety of species such as anti-Human SKP2, anti-Mouse SKP2. The species listed below are among those available. Click on a link to go to the corresponding products.

SKP2 Proteins by Source

Here you will find SKP2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SKP2 Proteins by Protein Type

Here you can find SKP2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SKP2 Proteins by Application

Find SKP2 Proteins validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SKP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320093
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320091
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095574
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120254
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2732125
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413499
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5711247
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1067220
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SKP2 Proteins

Wen, Wang, Yang: "Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 3917-24, (2016) (PubMed).

Aliases for SKP2 Proteins

S-phase kinase-associated protein 2 (p45) (Skp2) Proteins
S-phase kinase associated protein 2 (SKP2) Proteins
S-phase kinase associated protein 2 (Skp2) Proteins
FBL1 Proteins
FBXL1 Proteins
FLB1 Proteins
p45 Proteins
RGD1562456 Proteins
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