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SKP2 Proteins

(S-Phase Kinase-Associated Protein 2 (SKP2))

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class\; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2011].

recommended

SKP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2732125)

SKP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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recommended

SKP2 Protein (AA 1-424) (His tag) (ABIN3095574)

Crystallography grade SKP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

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recommended

SKP2 Protein (AA 1-424) (His tag) (ABIN3120254)

Crystallography grade SKP2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

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SKP2 Proteins by Grade

Find SKP2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SKP2 Proteins by Origin

Find SKP2 Proteins for a variety of species such as anti-Human SKP2, anti-Mouse SKP2. The species listed below are among those available. Click on a link to go to the corresponding products.

SKP2 Proteins by Source

Find SKP2 Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

SKP2 Proteins by Protein Type

Find SKP2 Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

SKP2 Proteins by Application

Find SKP2 Proteins validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SKP2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SKP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2732125

Quantity 20 μg

Datasheet Datasheet

SKP2 Protein (AA 1-424) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3095574

Quantity 1 mg

Datasheet Datasheet

SKP2 Protein (AA 1-424) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3120254

Quantity 1 mg

Datasheet Datasheet

SKP2 Protein (AA 1-424, full length) (His-SUMO Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5711247

Quantity 100 μg

Datasheet Datasheet

SKP2 Protein (AA 1-424) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1320091

Quantity 10 μg

Datasheet Datasheet

SKP2 Protein (AA 176-285) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1320093

Quantity 10 μg

Datasheet Datasheet

SKP2 Protein (AA 43-397) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7413499

Quantity 100 μg

Datasheet Datasheet

SKP2 Protein

Reactivity Human

Source

Validations

Cat. No. ABIN1067220

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our SKP2 Proteins

Wen, Wang, Yang: "Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 3917-24, (2016) (PubMed).

Aliases for SKP2 Proteins

S-phase kinase-associated protein 2 (p45) (Skp2) Proteins
S-phase kinase associated protein 2 (SKP2) Proteins
S-phase kinase associated protein 2 (Skp2) Proteins
FBL1 Proteins
FBXL1 Proteins
FLB1 Proteins
p45 Proteins
RGD1562456 Proteins

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SKP2 Proteins by Grade

SKP2 Proteins by Origin

SKP2 Proteins by Source

SKP2 Proteins by Protein Type

SKP2 Proteins by Application

Popular SKP2 Proteins

Latest Publications for our SKP2 Proteins

Aliases for SKP2 Proteins

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