Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) ELISA Kits

Human Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. The suppression of NHE1 (show SLC9A1 ELISA Kits) in esophageal squamous cell carcinoma (ESCC) may enhance malignant potential by mediating PI3K (show PIK3CA ELISA Kits)-AKT (show AKT1 ELISA Kits) signaling and epithelial-mesenchymal transition via Notch (show NOTCH1 ELISA Kits) signaling, and may be related to a poor prognosis in patients with ESCC.

2. Genetic disruption of the intracellular pH-regulating proteins Na+/H+ exchanger 1 (SLC9A1 (show SLC9A1 ELISA Kits)) and carbonic anhydrase 9 (show CA9 ELISA Kits) reduces the proliferation of colon cancer cells.

3. Hypoxia-induced MCT1 (show CMA1 ELISA Kits) supports glioblastoma glycolytic phenotype, being responsible for lactate efflux and an important mediator of cell survival and aggressiveness

4. NHE1 (show SLC9A1 ELISA Kits) mutation is associated with metastatic potential and epithelial-mesenchymal transition of triple-negative breast cancer.

5. our finding that the expression of MCT1 (show CMA1 ELISA Kits) and MCT4 is reduced in mutant IDH1 (show IDH1 ELISA Kits) gliomas highlights the unusual metabolic reprogramming that occurs in mutant IDH1 (show IDH1 ELISA Kits) tumors and has important implications for our understanding of these tumors and their treatment

6. The expression pattern of sNHE suggested that this protein may be involved in the regulation of sperm motility, and aberration of its expression in sperm may contribute to the pathogenesis of asthenozoospermia.

7. MCT1 (show CMA1 ELISA Kits) expression, independent of transporter activity, is required for growth factor-induced tumor cell motility.

8. TOMM20 (show TOMM20 ELISA Kits), MCT1 (show CMA1 ELISA Kits), and MCT4 expression was significantly different in Hodgkin and Reed Sternberg (HRS) cells. HRS have high expression of MCT1 (show CMA1 ELISA Kits), while tumor associated macrophages have absent MCT1 (show CMA1 ELISA Kits) expression. Tumor-infiltrating lymphocytes have absent MCT1 (show CMA1 ELISA Kits) expression. Reactive lymph nodes in contrast to cHL (show CHRDL1 ELISA Kits) tumors had low TOMM20 (show TOMM20 ELISA Kits), MCT1 (show CMA1 ELISA Kits), and MCT4 expression in lymphocytes and macrophages.

9. TOMM20 (show TOMM20 ELISA Kits) and MCT1 (show CMA1 ELISA Kits) were highly expressed in diffuse large B-cell lymphoma lymphocytes, indicating an OXPHOS phenotype, whereas non-neoplastic lymphocytes in the control samples did not express these markers.

10. Data show for the first time that PRLR (show PRLR ELISA Kits) activation stimulates breast cancer cell invasiveness via the activation of NHE1 (show SLC9A1 ELISA Kits). Data propose that PRL (show PRL ELISA Kits)-induced NHE1 (show SLC9A1 ELISA Kits) activation and the resulting NHE1 (show SLC9A1 ELISA Kits)-dependent invasiveness may contribute to the metastatic behavior of human breast cancer cells.

Zebrafish Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. Data indicate that monocarboxylate transporters (MCTs1 (show MCTS1 ELISA Kits)-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

Horse (Equine) Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. The expression of monocarboxylic acid transporter 1 (MCT1 (show MCTS1 ELISA Kits)), MCT2 (show SLC16A7 ELISA Kits), and CD147 in 3 horse breeds with different atheletic demands is reported.[MCT1 (show MCTS1 ELISA Kits); MCT2 (show SLC16A7 ELISA Kits)]

2. Results indicated that a single IET resulted in transient increases in MCT1 (show MCTS1 ELISA Kits) and MCT4 (show SLC16A3 ELISA Kits) mRNA expression and protein content in untrained and trained horses.

3. The coding sequence of MCT1 (show MCTS1 ELISA Kits), MCT4 (show SLC16A3 ELISA Kits), and CD147 in healthy horses, and the incidence of polymorphisms of these proteins in horses with excercise-induced myopathy are reported.

4. MCT1 (show MCTS1 ELISA Kits) protein content in GMM samples obtained when the horses were 24 months old was significantly higher than at 2 months of age. However, MCT4 (show SLC16A3 ELISA Kits) protein content remained unchanged throughout the study period.

Mouse (Murine) Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. Silencing or genetic deletion of MCT1 (show MCTS1 ELISA Kits) in vivo inhibited migration, invasion, and spontaneous metastasis.

2. It was concluded that both MCT1 (show MCTS1 ELISA Kits) and CAII (show CA2 ELISA Kits) are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1 (show MCTS1 ELISA Kits)(+/-) mice remain unexplained.

3. Exercise-induced changes in tumour LDH-B (show LDHB ELISA Kits) and MCT1 (show MCTS1 ELISA Kits) expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

4. Chronic lactate administration after exercise increases MCT1 (show MCTS1 ELISA Kits) protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (show GYS1 ELISA Kits) storage after exercise training.

5. This study showed that mouse MCT1 (show MCTS1 ELISA Kits), MCT2 (show SLC16A7 ELISA Kits), and MCT4 (show SLC16A3 ELISA Kits) are expressed in the PNS. While DRG neurons express MCT1 (show MCTS1 ELISA Kits), myelinating Schwann cells.

6. These data for the first time demonstrate that MCT1 (show MCTS1 ELISA Kits) is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush

7. in Parkinson's disease, the levels of MCT1 (show MCTS1 ELISA Kits), MCT2 (show SLC16A7 ELISA Kits) and GLUT1 (show SLC2A1 ELISA Kits) is not changed following dopaminergic neurodegeneration

8. results suggest that a reduction in mitochondria is a result, rather than the cause, of the metabolic deficiency observed in Basigin-null mice, and likely occurs because of reduced metabolic activity in the absence of MCT1 (show MCTS1 ELISA Kits) expression.

9. miR (show MLXIP ELISA Kits)-29a, miR (show MLXIP ELISA Kits)-29b selectively target MCT1 (show MCTS1 ELISA Kits) 3'UTR (show UTS2R ELISA Kits) ; the miR (show MLXIP ELISA Kits)-29 isoforms are highly expressed in islets and contribute to silencing Mct1 (show MCTS1 ELISA Kits) in beta cells; miR (show MLXIP ELISA Kits)-29 isoforms contribute to beta-cell-specific silencing of the MCT1 (show MCTS1 ELISA Kits) transporter and may affect insulin (show INS ELISA Kits) release

10. monocarboxylate transporter 1 (MCT1), is highly enriched within oligodendroglia and disruption of this transporter produces axon damage and neuron loss in animal and cell culture models; in addition, this same transporter is reduced in patients with, and in mouse models of, amyotrophic lateral sclerosis, suggesting a role for oligodendroglial MCT1 (show MCTS1 ELISA Kits) in pathogenesis

Cow (Bovine) Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. This study confirmed age-dependent changes of MCT1 (show MCTS1 ELISA Kits) expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.

2. These findings show that MCT 1 (show MCTS1 ELISA Kits) increases with the development of rumen function and also in adult animals MCT 1 (show MCTS1 ELISA Kits) may change with the feeding.

3. The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.

4. The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.