Solute Carrier Family 25 (Mitochondrial Carrier, Citrate Transporter), Member 1 Proteins (Slc25a1)

The mitochondrial tricarboxylate transporter (also called citrate transport protein, or CTP) is responsible for the movement of citrate across the mitochondrial inner membrane (Kaplan et al., 1993 [PubMed 8514800]).[supplied by OMIM, Jan 2011].. Additionally we are shipping Slc25a1 Antibodies (32) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Slc25a1 13358  
Rat Slc25a1 Slc25a1 29743 P32089
Slc25a1 6576 P53007
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Top Slc25a1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,493.38
Details
Escherichia coli (E. coli) Human GST tag Solute Carrier Family 25 (Mitochondrial Carrier, Citrate Transporter), Member 1 (Slc25a1) (AA 47-87), (partial) protein (GST tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 11 Days
$291.50
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human CTP Protein. 100 μg Log in to see 11 to 18 Days
$525.90
Details

Slc25a1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
, ,

More Proteins for Solute Carrier Family 25 (Mitochondrial Carrier, Citrate Transporter), Member 1 (Slc25a1) Interaction Partners

Mouse (Murine) Solute Carrier Family 25 (Mitochondrial Carrier, Citrate Transporter), Member 1 (Slc25a1) interaction partners

  1. binding of PPRE of CiC promoter by PPARalpha and PPARgammain vivo

Human Solute Carrier Family 25 (Mitochondrial Carrier, Citrate Transporter), Member 1 (Slc25a1) interaction partners

  1. SLC25A1 mutations might be associated with mitochondrial complex V deficiency and should be considered in the differential diagnosis of mitochondrial respiratory chain defects.

  2. SLC25A1 and ACLY upregulation suggests that metabolic reprogramming in Behcet's syndrome involves the citrate pathway dysregulation.

  3. tested the expression specificity of the Cochlin-tomoprotein by testing blood and CSF samples. The concentration was below the detection limit (0.2 ng/ml) in 38 of the 40 blood, and 14 of the 19 CSF samples

  4. Pathogenic mutations of the human mitochondrial citrate carrier SLC25A1 lead to impaired citrate export required for lipid, dolichol, ubiquinone and sterol synthesis.

  5. this study shows increased expression of SLC25A1 gene in cells from children with Down syndrome

  6. Altered metabolism in 22qDS reflected a critical role for the haploinsufficiency of the mitochondrial citrate transporter SLC25A1, further enhanced by HIF-1alpha, MYC, and metabolite controls.

  7. we report for the first time on a patient with a genetically confirmed diagnosis of SLC25A1 deficiency and treatment with either malate or citrate

  8. SLC25A1 has a key role in TNF-alpha and IFNgamma induced inflammation and is induced at the transcriptional level by these two inflammation mediators cytokines.

  9. We report for the first time a patient with a mitochondrial citrate carrier deficiency. Our data support a role for citric acid cycle defects in agenesis of corpus callosum

  10. Compares and contrasts all the known human SLC25A* genes and includes functional information.

  11. Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria.

  12. The mitochondrial citrate carrier (CIC) is present and regulates insulin secretion by human male gamete.

  13. muscular symptoms of CTP deficiency respond to creatine supplementation

  14. The mitochondrial citrate carrier: a new player in inflammation

  15. The results of molecular cloning of a citrate transporter from human normal prostate epithelial PNT2-C2 cells, is reported.

  16. Results suggest an evolutionary conserved role for Sea/SLC25A1 in the regulation of chromosome integrity.

  17. These results show that methylation, histone acetylation and Sp1 are important in the transcriptional regulation of the CIC proximal promoter.

  18. These results show that FOXA plays a role in the transcriptional regulation of CIC and in insulin secretion.

  19. CIC silencer activity extends over 26 bp (-595/-569), which specifically bind a protein ZNF224 present in HepG2 cell nuclear extracts.

Slc25a1 Protein Profile

Protein Summary

The mitochondrial tricarboxylate transporter (also called citrate transport protein, or CTP) is responsible for the movement of citrate across the mitochondrial inner membrane (Kaplan et al., 1993

Gene names and symbols associated with Slc25a1

  • solute carrier family 25 member 1 L homeolog (slc25a1.L)
  • solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a (slc25a1a)
  • solute carrier family 25 member 1 (slc25a1)
  • solute carrier family 25 member 1 (SLC25A1)
  • scheggia (sea)
  • solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 (Slc25a1)
  • solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 (Slc25a1)
  • solute carrier family 25 member 1 (Slc25a1)
  • 1300019P08Rik protein
  • 2610100G11Rik protein
  • AI194714 protein
  • anon-WO0140519.12 protein
  • CG6782 protein
  • CG31305 protein
  • Cic protein
  • CTP protein
  • D2L2AD protein
  • Dgsj protein
  • DmCIC protein
  • Dmel\\CG6782 protein
  • l(3)EP3364 protein
  • MGC53598 protein
  • NV14384 protein
  • SEA protein
  • SLC20A3 protein
  • SLC25A1 protein
  • zgc:63578 protein

Protein level used designations for Slc25a1

solute carrier family 25, member 1 , cic , solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 , solute carrier family 25 (mitochondrial carrier , CG6782-PA , CG6782-PC , CG6782-PD , CG6782-PE , sea-PA , sea-PC , sea-PD , sea-PE , DiGeorge syndrome gene j , tricarboxylate transport protein , citrate transport protein , citrate transporter) member 1 , mitochondrial tricarboxylate carrier , tricarboxylate transport protein, mitochondrial , solute carrier family 20 (mitochondrial citrate transporter), member 3 , tricarboxylate carrier protein , CTP , solute carrier family 25 member 1

GENE ID SPECIES
379891 Xenopus laevis
393579 Danio rerio
395026 Xenopus (Silurana) tropicalis
416764 Gallus gallus
458647 Pan troglodytes
608348 Canis lupus familiaris
719075 Macaca mulatta
3772221 Drosophila melanogaster
100118210 Nasonia vitripennis
13358 Mus musculus
29743 Rattus norvegicus
6576 Homo sapiens
100154310 Sus scrofa
282476 Bos taurus
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