anti-Solute Carrier Family 5 (Iodide Transporter), Member 6 (SLC5A6) Antibodies

Mouse (Murine) Solute Carrier Family 5 (Iodide Transporter), Member 6 (SLC5A6) interaction partners

1. This study shows for the first time that LPS (show TLR4 Antibodies) inhibits colonic biotin uptake via decreasing membrane expression of its transporter and that these effects likely involve a CK2 (show CSNK2A1 Antibodies)-mediated pathway.

2. S. typhimurium infection inhibits intestinal biotin uptake by SLC5A6, and that the inhibition is mediated via the action of proinflammatory cytokines.

3. These studies also provide evidence for a casual association between SMVT function and normal intestinal health

Human Solute Carrier Family 5 (Iodide Transporter), Member 6 (SLC5A6) interaction partners

1. This study shows for the first time that LPS (show IRF6 Antibodies) inhibits colonic biotin uptake via decreasing membrane expression of its transporter and that these effects likely involve a CK2 (show CSNK2A1 Antibodies)-mediated pathway.

2. S. typhimurium infection inhibits intestinal biotin uptake by SLC5A6, and that the inhibition is mediated via the action of proinflammatory cytokines.

3. SMVT-mediated transport is highly specific for R-(+)-alpha-lipoic acid.

4. SLC5A6 is responsible for the supplies of biotin and pantothenic acid into the brain across the blood brain barrier.

5. these studies demonstrated for the first time the functional and molecular expression of sodium dependent multivitamin transporter (SMVT) in human derived breast cancer (T47D) cells

6. This study shows for the first time the functional and molecular presence of SMVT in immortalized human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells

7. PCR analysis had confirmed the existence of FR-alpha (show FOLR1 Antibodies), SMVT, and B ((0, +)) in Y-79 and ARPE-19 cells.

8. This study for the first time confirms the molecular expression of SMVT and demonstrates that SMVT, responsible for biotin uptake, is functionally active in PC-3 (show PCSK1 Antibodies) prostate cancer cells

9. Cys (show DNAJC5 Antibodies)(294) is essential for the function of the human sodium-dependent multivitamin transporter.

10. Human SMVT protein is glycosylated, and that glycosylation is important for its function. The study also shows a role for the putative PKC-phosphorylation site Thr(286) of hSMVT in the PKC-mediated regulation of biotin uptake.