Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) ELISA Kits

SLC5A1 encodes a member of the sodium-dependent glucose transporter (SGLT) family. Additionally we are shipping Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Antibodies (125) and Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SLC5A1 6523 P13866
SLC5A1 25552 P53790
SLC5A1 20537 Q8C3K6
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Top Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 ELISA Kits at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
Details
Mouse 0.057 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$757.89
Details
Rat
  96 Tests Log in to see 2 to 3 Days
$713.90
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Pig
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details
Guinea Pig 1.0 ng/mL 25-500 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Rabbit 1.0 ng/mL 50-1000 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Dog
  96 Tests Log in to see 15 to 18 Days
$707.14
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Cow
  96 Tests Log in to see 15 to 18 Days
$707.14
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Chicken
  96 Tests Log in to see 15 to 18 Days
$707.14
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Monkey
  96 Tests Log in to see 15 to 18 Days
$707.14
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More ELISA Kits for Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Interaction Partners

Human Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. Sanger sequencing for the full coding regions of SLC5A1 resulted in the identification of 4 allelic variants in a homozygous state. Two mutations are novel and 2 have been previously reported to cause Congenital Glucose-Galactose Malabsorption

  2. SGLT1, SGLT2 and GLUT2 have roles in renal glucose handling [review]

  3. Only the index variant in SLC5A1 showed a significant association with fasting glucose in the expected opposing direction. Products of genes in all 1,5-AG-associated loci have known roles in carbohydrate digestion and enteral or renal glucose transport, suggesting that genetic variants associated with 1,5-AG influence its concentration via effects on glucose metabolism and handling

  4. High glucose levels induce MMP-2 expression in Human cardiac fibroblasts , possibly by up-regulation of SGLT1.

  5. Data suggest that a fraction of sodium glucose transporter is rapidly degraded by lysosomes and never reached the plasma membrane; another fraction reaches the membrane and is subsequently degraded by lysosomes following internalization.

  6. Data suggest expression of SGLT1 is markedly increased in kidney of patients with type 2 diabetes as compared to control subjects; SGLT1 mRNA is highly and significantly correlated with fasting and postprandial plasma glucose and HbA1c. In contrast, data suggest SGLT2 and GLUT2 mRNA in kidney are down-regulated in type 2 diabetes, but not to statistically significant level. (GLUT2 = glucose transporter type 2)

  7. Data suggest that SGLT2 expression is higher in control kidney than in kidney from subjects with type 2 diabetes; SGLT1 expression in kidney tended in the same direction; SGLT2 appears to be localized to tubular brush-border membranes; unaffected renal tissues were obtained from subjects undergoing unilateral nephrectomy for renal carcinomas.

  8. Duodenal SGLT-1 expression is increased in individuals with 1-hour postload hyperglycemia or impaired glucose tolerance, as well as in subjects with T2 Diabetes mellitus, and it positively correlates with early postload glucose excursion.

  9. Homoeriodictyol affects both the glucose metabolism and the serotonin system in Caco-2 cells via a sodium glucose cotransporter 1 protein (SGLT-1)-meditated pathway.

  10. intracellular Na+ and sugar release occurs in a random, independent manner

  11. Sodium-Glucose Cotransporter (hSGLT1) Is a Disulfide-Bridged Homodimer with a Re-Entrant C-Terminal Loop

  12. Binding of RS1-Reg to ODC1 inhibits the enzymatic activity at low intracellular glucose, which is blunted at high intracellular glucose.

  13. JAK3 up-regulates SGLT1 activity by increasing the carrier protein abundance in the cell membrane, an effect enforcing cellular glucose uptake into activated lymphocytes and thus contributing to the immune response.

  14. Results found that SGLT1 is required for FLIPL induced cell aerobic glycolysis and survival to low glucose conditions. In patients with hepatocellular carcinoma, SGLT1 expression level was positively correlated with FLIPL expression level.

  15. Although the similarity between the pf values of SGLT1 and aquaporin-1 makes a transcellular pathway plausible, it renders water pumping physiologically negligible because the passive flux would be orders of magnitude larger.

  16. Elevated SGLT activity increases Na+ influx into myocytes and causes Na+ overload in type 2 diabetes.

  17. Compound K induces SGLT1 expression and glucose uptake in differentiated intestinal Caco-2 cells.

  18. phlorizin binding domains in sodium-glucose cotransporter family

  19. Data demonstrate a role for Per1 in the transcriptional regulation of NHE3 and SGLT1 in the kidney.

  20. Cardiac SGLTs, possibly SGLT1 in particular, appear to provide an important protective mechanism against ischemia-reperfusion injury by replenishing ATP stores in ischemic cardiac tissues.

Mouse (Murine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. Loss or impairment of SGLT1 results in abnormal pancreatic islet (cyto)morphology and disturbed islet function regarding the insulin or glucagon release capacity from beta- or alpha-cells, respectively.

  2. FGF-21 regulates glucose level in diabetes partially due to inhibiting glucose absorption in the SI via inactivating SGK-1 pathway.

  3. In conclusion, the activation of JNK and p38 after cerebral ischemia caused an increase in cerebral SGLT-1. The regulation of cerebral SGLT-1 expression via the MAPK pathway may be a novel therapeutic strategy for cerebral ischemia patients.

  4. results suggest that rhythmic expression of Sglt1 is regulated at the mRNA transcriptional elongation level by enhancing the binding of the BRD4-P-TEFb complex to acetylated histones at the gene upon BMAL1-CLOCK binding to Sglt1

  5. SGLT1 deficiency turns Listeria infection into a lethal disease in mice.

  6. sodium influx through cerebral SGLT-1 may exacerbate cerebral ischemia-induced neuronal damage

  7. JAK3 up-regulates SGLT1 activity by increasing the carrier protein abundance in the cell membrane, an effect enforcing cellular glucose uptake into activated lymphocytes and thus contributing to the immune response.

  8. Enhanced cerebral sodium-glucose transporter function mediated by post-ischemic hyperglycemia exacerbates the development of cerebral ischemic neuronal damage.

  9. These findings support the involvement of SGLT1 in post-oral glucose and MDG conditioning.

  10. Compound K upregulates SGLT1 expression in vivo in mice.

  11. Studied leptin and CST modulation of SGLT1 expression in hyperleptinemic type 2 diabetic mice.

  12. Cardiac knockdown of SGLT1 in a murine model of PRKAG2 cardiomyopathy attenuates the disease phenotype, implicating SGLT1 in the pathogenesis. Overexpression of SGLT1 causes pathologic cardiac hypertrophy and left ventricular failure that is reversible.

  13. In conclusion, SPAK is a powerful negative regulator of SGLT1 protein abundance in the cell membrane and thus of electrogenic glucose transport.

  14. role of SGLT1 and GLUT2 in intestinal glucose transport and sensing

  15. These results suggest that cerebral SGLT is activated by post-ischemic hyperglycemia and may be involved in the exacerbation of ischemic neuronal damage.

  16. Improved glycemic control in mice lacking Sglt1 and Sglt2.

  17. Data suggest that the absence of intestinal microbiota alters expression of (i.e., up-regulates) Sglt1 and Tas1r3 in proximal small intestine, factors associated with increased consumption of nutritive sweet solutions.

  18. SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion.

  19. Data show that vitamin D treatment upregulates the expression of SGK1, which in turn enhances SGLT1 activity.

  20. Effect of cadmium on SGLT1 mRNA levels and alpha-methyl D-glucopyranoside uptake studied in mouse kidney cortical cells

Horse (Equine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. SGLT1 expression is enhanced, with time, 2-fold in the duodenum and 3.3-fold in the ileum for horses switched, gradually over a 2-month period, from low (<1.0 g/kg bwt/day) to high hCHO (6.0 g/kg bwt/day) diets of known composition.

Cow (Bovine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. Na+-dependent glucose cotransporter(SGLT)1 mRNA was most abundant in bovine intestine, at intermediate levels in bovine kidney, and at lower levels in bovine mammary gland, liver, and lung.

Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Antigen Profile

Antigen Summary

This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC5A1

  • solute carrier family 5 member 1 (SLC5A1) antibody
  • solute carrier family 5 (sodium/glucose cotransporter), member 1 (slc5a1) antibody
  • solute carrier family 5 member 1 (Slc5a1) antibody
  • solute carrier family 5 (sodium/glucose cotransporter), member 1 (Slc5a1) antibody
  • D22S675 antibody
  • NAGT antibody
  • Sglt1 antibody
  • SLC5A1 antibody
  • zgc:66074 antibody
  • zgc:85782 antibody

Protein level used designations for SLC5A1

Na+/glucose cotransporter 1 , high affinity sodium-glucose cotransporter , sodium/glucose cotransporter 1 , SGLT1 , solute carrier family 5 (sodium/glucose cotransporter), member 1 , Na(+)/glucose cotransporter 1 , cortical sodium-D-glucose cotransporter , solute carrier family 5 member 1 , solute carrier family 5, member 1 , sodium/glucose cotransporter 1-like , Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter) , sodium glucose cotransporter 1 , sodium-glucose cotransporter 1 , solute carrier family 5, member alpha 1 , sodium-glucose cotransporter-like 1 , Na+/glucose co-transporter , sodium/glucose cotransporter-like protein , Na+/glucose cotransporter , SGLT-1

GENE ID SPECIES
6523 Homo sapiens
393654 Danio rerio
458779 Pan troglodytes
717070 Macaca mulatta
100009262 Oryctolagus cuniculus
100137235 Papio anubis
100435495 Pongo abelii
100593847 Nomascus leucogenys
25552 Rattus norvegicus
20537 Mus musculus
492299 Canis lupus familiaris
100033952 Equus caballus
282361 Bos taurus
492300 Ovis aries
397113 Sus scrofa
395496 Gallus gallus
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