Sp5 Transcription Factor Proteins (SP5)

Binds to GC boxes promoters elements. Additionally we are shipping Sp5 Transcription Factor Antibodies (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SP5 SP5 296510  
SP5 389058 Q6BEB4
SP5 64406 Q9JHX2
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Top Sp5 Transcription Factor Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

SP5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Sp5 Transcription Factor (SP5) Interaction Partners

Zebrafish Sp5 Transcription Factor (SP5) interaction partners

  1. sp5 transcription factors mediate the downstream responses to Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling in several developmental processes in zebrafish.

Human Sp5 Transcription Factor (SP5) interaction partners

  1. human Sp5 is a member of Sp transcription factor family with a role in human cancers

Mouse (Murine) Sp5 Transcription Factor (SP5) interaction partners

  1. In triple KO mice, the HO-induced lung injury was associated with decreased surfactant protein (SP) A (show SFTPA1 Proteins) and SPC (show SFTPC Proteins) but not SPB and SPD (show SFTPD Proteins) expression.

  2. Functional studies revealed that knockdown of Nanog eliminated the mESC self-renewal-promoting ability of Sp5. Finally, we demonstrated that the self-renewal-promoting function of Sp5 was largely dependent on its zinc finger domains

  3. an intricate link between caveolin-1 (show CAV1 Proteins) and Src kinase (show CSK Proteins)-mediated cell signaling and alveolar epithelial cell apoptosis due to loss of SP-C (show SFTPC Proteins) expression through p53 (show TP53 Proteins) and uPA (show PLAU Proteins) system-mediated cross-talk, is reported.

  4. Sp5 is able to convert mouse epiblast stem cells into a naive pluripotent state.

  5. Sp5/8 bind directly to GC boxes in Wnt (show WNT2 Proteins) target gene enhancers and to adjacent, or distally positioned, chromatin-bound T-cell factor (Tcf) 1 (show HNF1A Proteins)/lymphoid enhancer factor (Lef) 1 (show LEF1 Proteins) to facilitate recruitment of beta-catenin (show CTNNB1 Proteins) to target gene enhancers.

  6. Sp5 and Sp8 (show SP8 Proteins) are pivotal downstream effectors of Wnt3a (show WNT3A Proteins)/beta-catenin (show CTNNB1 Proteins) that are essential for the self-renewal and differentiation of neuromesodermal stem cells.

  7. Data suggests that different SP-C (show SFTPC Proteins) mutations have unique consequences for interstitial lung diseases. Mutations here resulted in aberrant proSP-c products

  8. In vivo deficiency of SP-C (show SFTPC Proteins) leads to inflammation, increased cytokine production by type II cells, and persistent inflammation after repetitive LPS (show TLR4 Proteins) stimulation.

  9. Transgenic restoration of SP-C (show SFTPC Proteins) reduces inflammation and improves viral clearance in the lungs of SP-C (show SFTPC Proteins) deficient mice.

  10. The SPC H2B-GFP allele allowed the FACS-based enrichment and gene expression profiling of AT2 cells.

Sp5 Transcription Factor (SP5) Protein Profile

Protein Summary

Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo (By similarity).

Gene names and symbols associated with Sp5 Transcription Factor Proteins (SP5)

  • Sp5 transcription factor (Sp5)
  • Sp5 transcription factor a (sp5a)
  • Sp5 transcription factor (SP5)
  • Sp5 transcription factor (CpipJ_CPIJ003609)
  • trans-acting transcription factor 5 (Sp5)
  • bts1 protein
  • fc39b01 protein
  • wu:fc39b01 protein

Protein level used designations for Sp5 Transcription Factor Proteins (SP5)

transcription factor Sp5 , trans-acting transcription factor 5 , Sp5 transcription factor

296510 Rattus norvegicus
353154 Danio rerio
389058 Homo sapiens
512467 Bos taurus
609211 Canis lupus familiaris
693261 Gallus gallus
693989 Macaca mulatta
736052 Pan troglodytes
6035034 Culex quinquefasciatus
100024601 Monodelphis domestica
100587544 Nomascus leucogenys
64406 Mus musculus
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