anti-Sperm Associated Antigen 6 Antibodies

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization.

Data Quality
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Type
  • 32
    Primary
Target
  • 32
Reactivity
  • 32
  • 21
  • 19
  • 2
  • 2
Application
  • 19
  • 13
  • 5
  • 3
  • 1
Host
  • 28
  • 4
Clonality
  • 29
  • 3
Clone
  • 1
  • 1
  • 1
Binding Specificity
  • 3
  • 2
  • 2
  • 2
  • 2
Conjugate
  • 16
  • 2
  • 2
  • 1
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Isotype
  • 18
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Format
  • 23
  • 3
Suggested next Filters
32 Products
ReactivityHuman, Mouse, Rat
Application WB
Order details Cat. No. ABIN631997
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityCow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Order details Cat. No. ABIN2785513
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN564130
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN6133998
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN2152082
$510.36
50 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN523066
$425.71
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN523065
$440.00
50 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN523067
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Monkey
Application WB
Order details Cat. No. ABIN6745678
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityBat, Chicken, Cow, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application WB
Order details Cat. No. ABIN6743757
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman, Mouse, Rat
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN1714878
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
ReactivityHuman, Mouse, Rat
Application IHC (p), WB
Order details Cat. No. ABIN1701376
$407.00
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
ReactivityHuman, Mouse, Rat
Application ELISA, IP, WB
Order details Cat. No. ABIN5699047
$407.69
100 μg
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityHuman, Mouse, Rat
Application IF (p)
Order details Cat. No. ABIN5010901
$430.10
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
ReactivityHuman, Mouse, Rat
Application IF (p)
Order details Cat. No. ABIN5010902
$430.10
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
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Sperm Associated Antigen 6 (SPAG6) Antigen Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPAG6

  • sperm associated antigen 6 (SPAG6) antibody
  • sperm associated antigen 6-like (Spag6l) antibody
  • sperm associated antigen 6 (Spag6) antibody
  • sperm associated antigen 6 (spag6) antibody
  • sperm associated antigen 6 L homeolog (spag6.L) antibody
  • DKFZp459D035 antibody
  • PF16 antibody
  • repro-sa-1 antibody
  • RGD1310892 antibody
  • SPAG6 antibody
  • zgc:91805 antibody

Protein level used designations for SPAG6

axoneme central apparatus protein , protein PF16 homolog , sperm flagellar protein , sperm-associated antigen 6 , axoneme protein , sperm associated antigen 6

GENE ID SPECIES
9576 Homo sapiens
50525 Mus musculus
360747 Rattus norvegicus
420505 Gallus gallus
431757 Danio rerio
450348 Pan troglodytes
477978 Canis lupus familiaris
539424 Bos taurus
548730 Xenopus (Silurana) tropicalis
734748 Xenopus laevis
100134839 Meleagris gallopavo
100174630 Pongo abelii
100286811 Sus scrofa
100724896 Cavia porcellus