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SPAG8 Proteins

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization.

4 results:

Sperm Associated Antigen 8 (SPAG8) (AA 1-426) protein (His tag) Protein

SPAG8 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3095537
$10,223.08
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days
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Sperm Associated Antigen 8 (SPAG8) (AA 1-470) protein (His tag) Protein

SPAG8 Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3135120
$10,223.08
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days
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Sperm Associated Antigen 8 (SPAG8) (AA 1-501) protein (GST tag) Protein

SPAG8 Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1321064
$338.33
Plus shipping costs $45.00 and $24.00 dry ice
2 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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Sperm Associated Antigen 8 (SPAG8) (AA 321-421) protein (GST tag) Protein

SPAG8 Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1321065
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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  • Type Protein
    • Protein
  • Target Sperm Associated Antigen 8 (SPAG8)
    • Sperm Associated Antigen 8 (SPAG8)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • CD40 Ligand (CD40LG)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
    • Crystallization (Crys)
  • Reactivity
    • Human
    • Mouse
  • Images available
  • Host
    • Insect Cells
    • Wheat germ
  • Binding Specificity
    • AA 1-426
    • AA 1-470
    • AA 1-501
    • AA 321-421
  • Conjugate
    • Un-conjugated
    • GST tag
    • His tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid

SPAG8 Protein Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

Gene names and symbols associated with SPAG8

  • sperm associated antigen 8 (SPAG8) antibody
  • sperm associated antigen 8 (Spag8) antibody
  • BS-84 antibody
  • HSD-1 antibody
  • hSMP-1 antibody
  • MH-SPAG8 antibody
  • SMP1 antibody
  • SPAG3 antibody

Protein level used designations for SPAG8

sperm membrane protein 1 , sperm membrane protein BS-84 , sperm-associated antigen 8 , sperm associated antigen 8-like protein

GENE ID SPECIES
100067719 Equus caballus
26206 Homo sapiens
514627 Bos taurus
433700 Mus musculus
362508 Rattus norvegicus

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