Spermatogenesis Associated 13 Proteins

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases.

Data Quality
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Type
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    Protein
Target
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    Spermatogenesis Associated 13 (SPATA13)
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Application
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Reactivity
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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Suggested next Filters
2 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3095624
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3135187
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
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Spermatogenesis Associated 13 (SPATA13) Protein Profile

Protein Summary

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA (By similarity). Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Gene names and symbols associated with SPATA13

  • spermatogenesis associated 13 (SPATA13) antibody
  • spermatogenesis associated 13 (Spata13) antibody
  • ARHGEF29 antibody
  • ASEF2 antibody
  • C79050 antibody
  • ESTM11 antibody
  • mFLJ00298 antibody
  • X83327 antibody

Protein level used designations for SPATA13

APC-stimulated guanine nucleotide exchange factor 2 , adenomatous polyposis coli stimulated exchange factor 2 , spermatogenesis-associated protein 13 , asef2

GENE ID SPECIES
221178 Homo sapiens
219140 Mus musculus