Spermatogenesis Associated 13 Proteins

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases.

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Spermatogenesis Associated 13 (SPATA13) (AA 1-656) protein (His tag) Protein

SPATA13 Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Image no. 1 for Spermatogenesis Associated 13 (SPATA13) (AA 1-656) protein (His tag) (ABIN3135187)

Catalog No. ABIN3135187

$10,832.86

Plus shipping costs $45.00 and $24.00 dry ice

1 mg (More quantities available)

Shipping to: United States

Will be delivered in 60 Business Days

Details

Spermatogenesis Associated 13 (SPATA13) (AA 1-652) protein (His tag) Protein

SPATA13 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Image no. 1 for Spermatogenesis Associated 13 (SPATA13) (AA 1-652) protein (His tag) (ABIN3095624)

Catalog No. ABIN3095624

$10,832.86

Plus shipping costs $45.00 and $24.00 dry ice

1 mg (More quantities available)

Shipping to: United States

Will be delivered in 60 Business Days

Details

Spermatogenesis Associated 13 (SPATA13) Protein Profile

Protein Summary

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA (By similarity). Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Gene names and symbols associated with SPATA13

spermatogenesis associated 13 (SPATA13) antibody
spermatogenesis associated 13 (Spata13) antibody

ARHGEF29 antibody
ASEF2 antibody
C79050 antibody
ESTM11 antibody
mFLJ00298 antibody
X83327 antibody

Protein level used designations for SPATA13

APC-stimulated guanine nucleotide exchange factor 2 , adenomatous polyposis coli stimulated exchange factor 2 , spermatogenesis-associated protein 13 , asef2