Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 Proteins (SOHLH1)

Transcription factor expressed in undifferentiated spermatogonia required for spermatogonial development (By similarity).. Additionally we are shipping SOHLH1 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SOHLH1 402381 Q5JUK2
SOHLH1 227631 Q6IUP1
Rat SOHLH1 SOHLH1 362085  
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Top SOHLH1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
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Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$888.80
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SOHLH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 (SOHLH1) Interaction Partners

Human Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 (SOHLH1) interaction partners

  1. In glioblastoma (GBM) cell lines, cellular proliferation, migration, and invasion were significantly enhanced after Spermatogenesis- and oogenesis- specific basic helix-loop-helix transcription factor1 (Sohlh1) knockdown, but significantly inhibited after Sohlh1 overexpression.

  2. the expression of Sohlh genes in human tissues

  3. No association between SOHLH1 SNPs and azoospermia risk in the Chinese population.

  4. In Chinese and Serbian patients with primary ovarian insufficiency, SOHLH1 was found to be a candidate gene.

  5. Findings indicate that a splice-acceptor site mutation that probably causes a nonfunctional SOHLH1 protein results in nonobstructive azoospermia by the lack of normal spermatogenesis.

  6. Sohlh1 and Lhx8 are two germ cell-specific, critical regulators of oogenesis

Mouse (Murine) Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 (SOHLH1) interaction partners

  1. Sohlh1 and Sohlh2 are essential regulators of oocyte differentiation but do not affect meiosis I.

  2. SOHLH1 and SOHLH2 were able to directly and cooperatively repress STRA8 expression in cell lines in vitro through binding to its promoter.

  3. Our findings suggest that an SOHLH2/SOHLH1/SP1 ternary complex autonomously and cooperatively regulates Sohlh1 gene transcription through juxtaposed E- and GC-boxes during early spermatogenesis and oogenesis.

  4. SOHLH1 and SOHLH2 directly stimulate Kit transcription in postnatal spermatogonia, thus activating the signaling involved in spermatogonia differentiation and spermatogenetic progression.

  5. SOHLH1 and SOHLH2 suppress genes involved in spermatogonial stem cell maintenance, and induce genes important for spermatogonial differentiation.

  6. Sohlh1 represents the first testis-specific bHLH transcription factor that is essential for spermatogonial differentiation.

  7. Sohlh1 and Lhx8 are two germ cell-specific, critical regulators of oogenesis

SOHLH1 Protein Profile

Protein Summary

Transcription factor expressed in undifferentiated spermatogonia required for spermatogonial development (By similarity).

Gene names and symbols associated with SOHLH1

  • spermatogenesis and oogenesis specific basic helix-loop-helix 1 (SOHLH1)
  • spermatogenesis and oogenesis specific basic helix-loop-helix 1 (Sohlh1)
  • bA100C15.3 protein
  • bHLHe80 protein
  • C9orf157 protein
  • Gm110 protein
  • Nohlh protein
  • RGD1564440 protein
  • SPATA27 protein
  • TEB2 protein

Protein level used designations for SOHLH1

newborn ovary helix loop helix , spermatogenesis associated 27 , spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 , helix-loop-helix protein NOHLH

GENE ID SPECIES
402381 Homo sapiens
227631 Mus musculus
526069 Bos taurus
362085 Rattus norvegicus
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