anti-Spermidine/spermine N1-Acetyltransferase 1 (SAT1) Antibodies

The protein encoded by SAT1 belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. Additionally we are shipping SAT1 Kits (20) and SAT1 Proteins (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SAT1 6303 P21673
SAT1 20229 P48026
SAT1 302642  
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Top anti-SAT1 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Detection of SAT1 in human SAT1 transfected lysate using ABIN258375. Immunohistochemistry: SAT1 Antibody [ABIN2583752] - IHC analysis of SAT1 in mouse seminal vesical (left) and prostate (right) usind DAB with hematoxylin counterstain, 0.1 mL Log in to see 7 to 9 Days
$485.88
Details
Human Mouse Un-conjugated ELISA, WB SAT polyclonal antibody (A01), Lot # 051213JC01. Western Blot analysis of SAT expression in MCF-7. SAT polyclonal antibody (A01), Lot # 051213JC01. Western Blot analysis of SAT expression in NIH/3T3. 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg Log in to see 13 to 16 Days
$380.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$334.02
Details
Human Mouse Un-conjugated ICC, IF, WB Immunocytochemistry/Immunofluorescence: SAT1 Antibody (2E6) [NBP2-01331] Staining of COS7 cells transiently transfected by pCMV6-ENTRY SAT1. Western Blot: SAT1 Antibody (2E6) [NBP2-01331] - E.coli lysate (5 ug, left lane) and E.coli lysate expressing human recombinant protein fragment (5 ug, right lane) corresponding to amino acids 4-171 of human SAT1(NP_002961) were separated by SDS-PAGE and immunoblotted with anti- SAT1. 0.1 mL Log in to see 8 to 11 Days
$556.31
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB 100 μL Log in to see 6 to 7 Days
$555.07
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: SAT1 Antibody [NBP2-37947] - Staining of human testis shows distinct cytoplasmic positivity in cells in seminiferous ducts. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Chicken Rabbit DyLight 550 IHC, IHC (p), WB   0.1 mL Log in to see 7 to 9 Days
$585.06
Details
Chicken Rabbit DyLight 405 IHC, IHC (p), WB   0.1 mL Log in to see 7 to 9 Days
$585.06
Details

SAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SAT1 Antibodies

  1. Cow (Bovine) Polyclonal SAT1 Primary Antibody for IHC, IHC (p) - ABIN258375 : Liao, Lasbury, Wang, Zhang, Durant, Murakami, Matsufuji, Lee: Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages. in The Journal of biological chemistry 2009 (PubMed)

More Antibodies against SAT1 Interaction Partners

Human Spermidine/spermine N1-Acetyltransferase 1 (SAT1) interaction partners

  1. Activation of SAT1 expression induces lipid peroxidation and sensitizes cells to undergo ferroptosis upon reactive oxygen species (ROS (show ROS1 Antibodies))-induced stress, which also leads to suppression of tumor growth in xenograft tumor models. Notably, SAT1 expression is down-regulated in human tumors, and CRISPR-cas9-mediated knockout of SAT1 expression partially abrogates p53 (show TP53 Antibodies)-mediated ferroptosis. Moreover, SAT1 induction is correlated

  2. our results indicated depletion of polyamines by SSAT signi fi cantly inhibited cell proliferation, migration and invasion through AKT (show AKT1 Antibodies)/GSK3beta/beta-catenin (show CTNNB1 Antibodies) signaling pathway in hepatocellular carcinoma and colorectal cancer cells.

  3. SLC26A1 L348P was associated with lower whole-body bone mineral density (BMD) and higher serum calcium, consistent with the osteochondrodysplasia exhibited by dogs and sheep with naturally occurring, homozygous, loss-of-function mutations in Slc13a1

  4. Extracellular polyamines induced proliferation and cancer cell migration by inducing ODC (show ODC1 Antibodies) and SSAT expression, and the Akt1 (show AKT1 Antibodies)-mediated pathway.

  5. Human SLC26A1 (show SLC26A1 Antibodies) resembles SLC26 paralogs in its inhibition.

  6. Mutations in SLC26A1 (show SLC26A1 Antibodies) gene is associated with Nephrolithiasis.

  7. we used siRNA on SSAT and compared the SSAT level in knockdown and normal cells. Results showed that the monoclonal antibody specifically recognized SSAT.

  8. 4H6 was also compared with the commercial antibody. The produced mAbs will be a useful tool for further investigation of SSAT functions in organisms.

  9. Results show low SAT1 brain expression in depressed suicides and implicate low SAT1 brain expression in major depression independent of suicide

  10. Data suggest that SAT1 plays role in apoptosis; overexpression of SAT1 in human embryonic kidney cell line leads to a rapid depletion of spermidine and spermine, arrest in cell growth, and mitochondria-mediated apoptosis.

Mouse (Murine) Spermidine/spermine N1-Acetyltransferase 1 (SAT1) interaction partners

  1. the level of SSAT enzyme activity affected osteoblastogenesis and hence influenced bone remodeling and the bone phenotype in mice

  2. Enhanced SSAT expression by proximal tubule epithelial cells leads to tubular damage, and its deficiency reduces the severity of renal I/R injury through reduction of cellular damage and modulation of the innate immune response

  3. The SSAT overexpression and the concomitantly accelerated polyamine metabolism in hematopoietic cells and bone marrow microenvironment affect lineage commitment and lead to the development of a mouse myeloproliferative disease in SSAT mice.

  4. the results indicate that transcriptional modulation of the SAT1 gene is not a significant component of the hyperoxaluria observed in these rat models

  5. study suggests that SSAT overexpression obtained in SSAT mice enhances the anti-inflammatory actions in the acute phase of LPS (show TLR4 Antibodies)-induced immune response

  6. Expression of SSAT increases in kidneys subjected to endotoxic acute kidney injury and that increased polyamine back conversion and oxidation contribute to tubular damage in endotoxin-induced AKI.

  7. increased SSAT expression solely accompanies the proliferative response of mouse kidney, and suggest the importance of post-transcriptional regulation to the control of SSAT activity

  8. Testosterone treatment enhanced AZ1 (show AZI1 Antibodies) and N1-SSAT mRNA levels in a time-dependent manner

  9. antiproliferative and metabolic consequences of SSAT overexpression in a prostate cancer model

  10. cutaneous changes of SSAT transgenic animals are due to disorders of the keratinocyte differentiation.

SAT1 Antigen Profile

Protein Summary

This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified.

Gene names and symbols associated with SAT1

  • spermidine/spermine N1-acetyltransferase 1 (SAT1) antibody
  • solute carrier family 26 member 1 (SLC26A1) antibody
  • spermidine/spermine N1-acetyltransferase 1 L homeolog (sat1.L) antibody
  • spermidine/spermine N1-acetyltransferase 1 (sat1) antibody
  • spermidine/spermine N1-acetyl transferase 1 (Sat1) antibody
  • spermidine/spermine N1-acetyltransferase 1 (Sat1) antibody
  • AA617398 antibody
  • Ab2-402 antibody
  • dc21 antibody
  • EDM4 antibody
  • kfsd antibody
  • kfsdx antibody
  • Sat antibody
  • SAT-1 antibody
  • sat1 antibody
  • sat1b antibody
  • ssat antibody
  • ssat-1 antibody

Protein level used designations for SAT1

diamine N-acetyltransferase 1 , diamine acetyltransferase 1 , polyamine N-acetyltransferase 1 , putrescine acetyltransferase , spermidine/spermine N(1)-acetyltransferase 1 , spermidine/spermine N1-acetyltransferase alpha , solute carrier family 26 (sulfate transporter), member 1 , sulfate anion tranporter AT1 , sulfate anion transporter 1 , sulfate/anion transporter SAT-1 protein , SSAT , SSAT-1 , spermidine/spermine N-acetyltransferase , diamine N-acetyltransferase 1 b , spermidine/spermine N1-acetyltransferase 1 b , spermidine/spermine N1-acetyltransferase 1 , Spermidine / spermine N1-acyltransferase (diamine acetyltransferase) , Polyamine N-acetyltransferase 1 , Putrescine acetyltransferase , Spermidine/spermine N(1)-acetyltransferase 1

GENE ID SPECIES
6303 Homo sapiens
10861 Homo sapiens
374006 Gallus gallus
397645 Sus scrofa
447322 Xenopus laevis
480865 Canis lupus familiaris
493359 Xenopus (Silurana) tropicalis
508861 Bos taurus
20229 Mus musculus
302642 Rattus norvegicus
100689427 Cricetulus griseus
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