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May act as a protease inhibitor to modulate the host immune response against tumor cells.. Additionally we are shipping Squamous Cell Carcinoma Antigen 1 Antibodies (6) and Squamous Cell Carcinoma Antigen 1 Proteins (3) and many more products for this protein.
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While novel diagnostic tumour markers are urgently needed, the examined potential tumour markers, with the exception of PIVKAII seem to be inadequate for diagnosing HCC in ALC
Results provide the first evidence that failure of serum SCCA to fall into the normal range by the fourth week of definitive radiotherapy is associated with significantly increased risk of recurrence and death.
The combination of SCCA-IgM with common clinical data shows promising diagnostic performance for the detection of Non-alcoholic steato-hepatitis in hepatitis C virus patients
Both periostin and SCCA may play a role in the pathogenesis of acute bronchitis due to respiratory syncytial virus
iron overload and was previously found capable of up-regulating SerpinB3 at the transcriptional level.
the SCCA-IgM determination could be helpful in predicting the response to therapy in patients with hepatocellular carcinoma.
Serum SCC-Ag, hs-CRP, and CA-125 were higher in recurrence cervical patients which could be potential biomarkers for predicting cervical cancer recurrence risk.
A close connection between SerpinB3 and DPPPIV has been identified, but further studies are required to better understand the mechanism by which these proteins communicate and exert metabolic effects in hepatocellular carcinoma.
Findings point to potential interest of squamous cell carcinoma antigen SERPINB3/B4 for the stratification of head and neck squamous cell carcinoma (HNSCC) patients in the therapeutic context.
Serum SCCA2 levels reflected disease severity and clinical type of atopic dermatitis. Serum SCCA2 may thus be a relevant biomarker for atopic dermatitis.
role of SERPINB3/B4 mutations in immunotherapy response
Data show that in colorectal cancer SerpinB3, COX-2 and beta-Catenin are positively correlated and associated with more advanced tumor stage.
Results showed no correlation between gestational age and vaginal fluid SCC levels. There was no significant difference in vaginal fluid SCC levels between patients with premature rupture of membranes and those with control pregnant women.
Serum SCC-Ag level was an important predictor for the cervical squamous carcinoma recurrence and prognosis.
Data indicate that serum tumor markers showed significant shorter 3-year progression-free survival (PFS) in higher levels compared to lower levels for S-CYFRA 21-1 (cytokeratin 19 fragment), S-SCCA and S-CEA.
serum level is a reliable diagnostic marker to distinguish sinonasal inverted papilloma from inflammatory disease
SerpinB3 indirectly increased the transcription of Myc through the induction of Yap pathway.
May act as a protease inhibitor to modulate the host immune response against tumor cells.
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3
, serpin B3
, squamous cell carcinoma antigen 1
, SCCA2/SCCA1 fusion protein
, peptidase inhibitor 11
, protease inhibitor (leucine-serpin)
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4
, serpin B4
, squamous cell carcinoma antigen 2