anti-Src-Like-Adaptor (SLA) Antibodies

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis (By similarity).. Additionally we are shipping Src-Like-Adaptor Kits (6) and Src-Like-Adaptor Proteins (6) and many more products for this protein.

Gene Name	GeneID	UniProt
SLA	6503	Q13239
SLA	338477	P59622
SLA	20491	Q60898

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Top anti-Src-Like-Adaptor Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN2776658	Cow	Rabbit	Un-conjugated	IHC, WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN2775348	Cow	Rabbit	Un-conjugated	IHC, WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN959027	Cow	Rabbit	Un-conjugated	IHC, IHC (p), WB	50 μg	Log in to see	11 to 14 Days	$727.83	Details
ABIN1104304	Human	Rabbit	Un-conjugated	IHC, IHC (p)	50 μg	Log in to see	11 to 14 Days	$484.00	Details
ABIN520218	Human	Mouse	Un-conjugated	WB	50 μL	Log in to see	11 to 12 Days	$440.00	Details
ABIN630654	Human	Rabbit	Un-conjugated	WB	50 μg	Log in to see	9 to 11 Days	$473.93	Details
ABIN265047	Human	Rabbit	Un-conjugated	WB	0.1 mg	Log in to see	6 to 8 Days	$467.50	Details
ABIN6389340	Human	Rabbit	Un-conjugated	ELISA, WB	100 μL	Log in to see	16 Days	$293.00	Details
ABIN1828893	Human	Mouse	Un-conjugated	ELISA, WB	100 μg	Log in to see	11 to 14 Days	$537.17	Details
ABIN562885	Human	Mouse	Un-conjugated	ELISA, WB	50 μL	Log in to see	11 to 12 Days	$305.71	Details

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More Antibodies against Src-Like-Adaptor Interaction Partners

Human Src-Like-Adaptor (SLA) interaction partners

results suggest that cytoplasm-specific transduction of the SH3 and SH2 domains of SLAP has a therapeutic potential of being an immunosuppressive reagent for the treatment of various autoimmune diseases
Taken together the data demonstrate that SLAP negatively regulates wild-type c-Kit signaling, but not its oncogenic counterpart, indicating a possible mechanism by which the oncogenic c-Kit bypasses the normal cellular negative feedback control
upon ligand stimulation SLAP stably associates with Flt3 through multiple phosphotyrosine residues in Flt3. SLAP mRNA is differentially expressed in different cancers and its expression significantly increased in patients carrying the Flt3-ITD mutation
These data provide evidence for src-like adaptor protein-dependent regulation of CD3 zeta-chain in the fine control of TCR signaling.
Although SLA is a prominent glucocorticoids response gene, it does not seem to contribute to the anti-leukemic effects of glucocorticoids.
The SLA molecule and its functionally relevant residues have been highly conserved throughout the evolution.

Mouse (Murine) Src-Like-Adaptor (SLA) interaction partners

SLAP and SLAP2 are critical inhibitors of platelet (hem)ITAM signaling in the setting of arterial thrombosis and ischemic stroke
SLAP is a critical regulator of B-cell development and function and its deficiency leads to decreased autoreactive B cells that are otherwise maintained by inefficient receptor editing or failed negative selection.
Src-like adaptor protein (SLAP) functions as a negative regulator of the granulocyte-macrophage colony-stimulating factor receptor (GM-CSFR) generation of monocyte-derived dendritic cells of bone marrow origin.
SLAP deficiency dramatically reduces both the incidence and severity of arthritis and prevents development of chronic arthritis in the double SKG (mutant ZAP70) Src-like adapter protein (SLAP) knockout mouse model.
SLAP negatively regulates differentiation of osteoclasts and proliferation of their precursors.
SLAP functions in a pathway that requires the phosphorylated TCRzeta chain and the Src family kinase Lck, but not ZAP-70 (zeta-associated protein of 70 kD).
SLAP has a conserved function in B and T cells by adapting c-Cbl to the antigen-receptor complex and targeting it for degradation

Src-Like-Adaptor (SLA) Antigen Profile

Protein Summary

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis (By similarity).

Gene names and symbols associated with anti-Src-Like-Adaptor (SLA) Antibodies

Src like adaptor (SLA) antibody
Src-like-adaptor (SLA) antibody
src-like adaptor (Sla) antibody
Src like adaptor (Sla) antibody

SLA antibody
SLA1 antibody
Slap antibody
Slap-1 antibody
Slap1 antibody
src-like-adapter antibody

Protein level used designations for anti-Src-Like-Adaptor (SLA) Antibodies

SLAP-1 , hSLAP , src-like-adapter , src-like-adapter protein 1 , src-like adaptor , Src-like-adaptor , mSLAP , src-like adapter protein , src-like adaptor protein

GENE ID	SPECIES
6503	Homo sapiens
378908	Gallus gallus
464409	Pan troglodytes
608259	Canis lupus familiaris
697377	Macaca mulatta
100223615	Taeniopygia guttata
100339379	Oryctolagus cuniculus
338477	Rattus norvegicus
513589	Bos taurus
20491	Mus musculus
100721511	Cavia porcellus

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