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May be involved in proliferation or differentiation of keratinocytes in the skin (By similarity)..
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SRMS phosphorylated the C terminus of BRK (show PTK6 Proteins), but not SRC (show SRC Proteins).
The unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate docking protein 1 (show DOK1 Proteins).
The tyrosine kinases Brk/PTK6/Sik (show PTK6 Proteins), Srm (show SRM Proteins), Frk/Rak/Gtk (show FRK Proteins)/Iyk/Bsk (show EPHA5 Proteins), and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases. The exon structure of these kinases, called the Brk (show PTK6 Proteins) family, is highly conserved and distinct.
May be involved in proliferation or differentiation of keratinocytes in the skin (By similarity).
tyrosine-protein kinase Srms