Stonin 1 Proteins (STON1)

Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants.

• stonin 1 (STON1)
• stonin 1 (ston1)
• stonin 1 (Ston1)

• 4921524J06Rik protein
• C86231 protein
• DKFZP469K176 protein
• Salf protein
• Sblf protein
• Show all synonym aliases
• STN1 protein
• STNB1 protein

stoned B homolog 1 , stoned B-like factor , stoned-b1 , stonin-1 , stonin 1 , stonin-1-like , stoned B/TFIIA-alpha/beta-like factor