Sulfite Oxidase Proteins (SUOX)

Human Sulfite Oxidase (SUOX) interaction partners

1. SUOX is negatively associated with the progression and proliferation of oral squamous cell carcinoma.

2. This is the first description of the prenatal neurodevelopment of brain disruption in isolated sulfite oxidase deficiency.

3. Novel SUOX mutations were detected in 3 Sulfite oxidase deficiency cases

4. Nitrite binds and reduces at the molybdenum site of mammalian sulfite oxidase, which may be allosterically regulated by heme and molybdenum domain interactions, and contributes to the mammalian nitrate-nitrite-NO signaling pathway in human fibroblasts.

5. This finding suggests the possibility to use oxygen-reactive SO variants in sulfite detoxification, as the loss of SO activity is causing severe neurodegeneration

6. Several mutants of H304 and R309 of SUOX were investigated by steady-state kinetics, laser flash photolysis studies of intramolecular electron transfer (IET), and spectroelectrochemistry.

7. SUOX was decreased and AKR1B10 (show AKR1B10 Proteins) and CD34 (show CD34 Proteins) were increased with the stepwise progression of hepatocarcinogenesis.

8. combined genetic association studies in women from China/Netherlands/United States: Data suggest that an SNP in SUOX locus (rs705702) and SNPs in other proteins are associated with polycystic ovary syndrome across ethnic differences. [META-ANALYSIS]

9. In this study a human sulfite oxidase variant, in which the active site has been modified to alter substrate specificity and activity from sulfite oxidation to nitrate reduction, is compared to chicken sulfite oxidase.

10. prepared and purified samples of the wild type and various mutants of human SO that are depleted of chloride. These samples do not exhibit the typical lpH (show LCT Proteins) EPR (show EREG Proteins) spectrum at low pH but rather exhibit spectra that are characteristic of the blocked species

Mouse (Murine) Sulfite Oxidase (SUOX) interaction partners

1. This finding suggests the possibility to use oxygen-reactive SO variants in sulfite detoxification, as the loss of SO activity is causing severe neurodegeneration

Cow (Bovine) Sulfite Oxidase (SUOX) interaction partners

1. A single base insertion leading to a premature stop codon in the SUOX is associated with the arachnomelia phenotype.

Arabidopsis thaliana Sulfite Oxidase (SUOX) interaction partners

1. the significance of sulfite oxidase for the overall shoot response to SO2 in relation to alterations in plant phenology and physiology

2. In contrast to chicken sulfite oxidase (SO), Arabidopsis SO crystallizes without a sulfate bound in the active site.

3. structural analysis of the Mo(V) forms of sulfite oxidase from Arabidopsis thaliana

4. Could be responsible for removing sulfite as a toxic metabolite, which might represent a means to protect the cell against excess of sulfite derived from SO2 gas in the atmosphere (acid rain) or during the decomposition of sulfur-containing amino acids.

5. AtSO is expressed mainly in the green tissues/organs in a light-dependent way

6. The isotropic hfi constant of 33S determined in these experiments was about 3 MHz, which demonstrates the presence of coordinated sulfate in the sulfite-reduced low-pH form of the plant enzyme.