Suppression of Tumorigenicity 5 Proteins
ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice.
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Suppression of Tumorigenicity 5 (ST5) (AA 1-1137) protein (His tag) Protein
Suppression of Tumorigenicity 5 (ST5) (AA 1-1134) protein (His tag) Protein
Suppression of Tumorigenicity 5 (ST5) (AA 1038-1135) protein (GST tag) Protein
Suppression of Tumorigenicity 5 (ST5) Protein Profile
Protein Summary
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Gene names and symbols associated with ST5
- suppression of tumorigenicity 5 (st5) antibody
- suppression of tumorigenicity 5 (ST5) antibody
- suppression of tumorigenicity 5 (St5) antibody
- 2010004M01Rik antibody
- 2610305K15Rik antibody
- DENND2B antibody
- DKFZp459D1230 antibody
- HTS1 antibody
- p126 antibody
- si:ch211-208c6.1 antibody
- ST5 antibody
- wu:fc11b09 antibody
- zgc:91902 antibody
Protein level used designations for ST5
suppression of tumorigenicity 5 , suppression of tumorigenicity 5 protein , DENN/MADD domain containing 2B , heLa tumor suppression 1 , DENN domain-containing protein 2B
GENE ID | SPECIES |
---|---|
323827 | Danio rerio |
451727 | Pan troglodytes |
705444 | Macaca mulatta |
100172031 | Pongo abelii |
100216092 | Xenopus (Silurana) tropicalis |
100226736 | Taeniopygia guttata |
100380403 | Salmo salar |
6764 | Homo sapiens |
76954 | Mus musculus |
423055 | Gallus gallus |
485380 | Canis lupus familiaris |
537907 | Bos taurus |
308944 | Rattus norvegicus |
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