Suppressor of IKBKE 1 Proteins (SIKE1)

SIKE interacts with IKK-epsilon (IKBKE\; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]..

list all proteins Gene Name GeneID UniProt
Human SIKE1 SIKE1 80143 Q9BRV8
Mouse SIKE1 SIKE1 66641 Q9CPR7
Rat SIKE1 SIKE1 362007 Q5FWT9
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Top Suppressor of IKBKE 1 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,508.00
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Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,508.00
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,508.00
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Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$2,508.00
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Escherichia coli (E. coli) Human His tag   0.5 mg Log in to see 13 to 16 Days
$953.85
Details

More Proteins for Suppressor of IKBKE 1 (SIKE1) Interaction Partners

Human Suppressor of IKBKE 1 (SIKE1) interaction partners

  1. Data indicate that suppressor of IKKepsilon (show IKBKE Proteins) (SIKE) inhibits TANK-binding kinase 1 (TBK1 (show TBK1 Proteins))-mediated phosphorylation of interferon regulatory factor 3 (IRF3 (show IRF3 Proteins)), which is essential to type I interferon (show IFNA Proteins) production.

  2. Overexpression of SIKE inhibits virus- and Toll-like receptor 3 (show TLR3 Proteins)-triggered interferon (show IFNA Proteins)-stimulated response elements (ISRE) but not NF-kappa B (show NFKB1 Proteins) activation.

Suppressor of IKBKE 1 (SIKE1) Protein Profile

Protein Summary

SIKE interacts with IKK-epsilon (IKBKE\; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005

Gene names and symbols associated with Suppressor of IKBKE 1 Proteins (SIKE1)

  • suppressor of IKBKE 1 (SIKE1)
  • suppressor of IKBKE 1 (Sike1)
  • 2810005O12Rik protein
  • 5730470L24Rik protein
  • AI450236 protein
  • AI839862 protein
  • RGD1311316 protein
  • Sike protein
  • Sikeb protein

Protein level used designations for Suppressor of IKBKE 1 Proteins (SIKE1)

suppressor of IKK epsilon , suppressor of IKK-epsilon , Suppressor of IKK-epsilon

GENE ID SPECIES
506848 Bos taurus
80143 Homo sapiens
66641 Mus musculus
362007 Rattus norvegicus
100173065 Pongo abelii
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