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Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. Additionally we are shipping SUV39H2 Antibodies (116) and many more products for this protein.
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Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes (By similarity).
, histone H3-K9 methyltransferase 2
, histone-lysine N-methyltransferase SUV39H2
, lysine N-methyltransferase 1B
, su(var)3-9 homolog 2
, Suv39h histone methyltransferase
, suppressor of variegation 3-9 homolog 2 (Drosophila)
, histone-lysine N-methyltransferase SUV39H2-like